- Network Security and Intrusion Detection
- Cooperative Communication and Network Coding
- RNA modifications and cancer
- Corporate Finance and Governance
- Asthma and respiratory diseases
- Electric and Hybrid Vehicle Technologies
- Advanced Wireless Communication Techniques
- Internet Traffic Analysis and Secure E-voting
- Cancer-related molecular mechanisms research
- Error Correcting Code Techniques
- RNA Interference and Gene Delivery
- Artificial Immune Systems Applications
- Advanced Battery Technologies Research
- Neonatal Respiratory Health Research
- Data Visualization and Analytics
- Nanoparticle-Based Drug Delivery
- Advanced Wireless Network Optimization
- Cancer-related Molecular Pathways
- Advanced biosensing and bioanalysis techniques
- Geographic Information Systems Studies
- Cancer-related gene regulation
- Political Influence and Corporate Strategies
- Human Motion and Animation
- Respiratory Support and Mechanisms
- Antifungal resistance and susceptibility
Research Center for Eco-Environmental Sciences
2024
National Tsing Hua University
2018-2024
University of Chinese Academy of Sciences
2024
First Affiliated Hospital Zhejiang University
2019-2023
Beijing Institute of Technology
2020-2023
Zhejiang University
2021-2023
Chongqing Normal University
2022-2023
China Academy of Launch Vehicle Technology
2023
Singapore University of Technology and Design
2023
Nanjing University
2017-2019
Acute lung injury is the most serious and fatal complication of elderly patients with hip fracture, but mechanisms are unknown. Recent studies demonstrated mitochondrial DNA (mtDNA) release was associated after trauma. This study aimed to examine differential mtDNA between younger rats suffering from fracture investigate possible mechanism in induced by fracture. In first part study, we investigated effects on rats. The rats, respectively, received operations. degree evaluated, toll-like...
Asthma is one of the most common chronic diseases that affects more than 300 million people worldwide. Though asthma can be well controlled, individuals with severe experience recurrent exacerbations and impose a substantial economic burden on healthcare system. Neutrophil inflammation often occurs in patients who have poor response to glucocorticoids, increasing difficulty clinical treatment.We established several neutrophil-dominated allergic mouse models, analyzed airway...
The tumor-associated inflammatory microenvironment plays a pivotal role in human non-small cell lung cancer (NSCLC) development. FGFR1 and TLR4 involve the regulation of NSCLC.However, relationship between signaling mechanisms that involved are still unclear. We investigated expression cancerous tissues noncancerous from 60 primary NSCLC patients using immunohistochemical staining. Three lines (A549, PC-9 SK-MES-1) were used for vitro studies. demonstrated was significantly correlated...
Conventional concept suggests that immediate surgery is the optimal choice for elderly hip fracture patients; however, few studies focus on adverse effect of surgery. This study aims to examine surgery, as well explore meaning mtDNA release after trauma. In experiment, rats, respectively, received operations or plus intramedullary nail After operations, serum levels related indicators systemic inflammatory response and lung injury significantly increased in rats. above variables were further...
Parvimonas micra (P. micra) is a Gram-positive anaerobic bacterium distributed in the oral cavity, with potential to become pathogenic causing lung abscess. Due lack of specificity symptoms and difficulty culture, diagnosis abscess associated P. delayed. It essential elucidate clinical characteristics micra.From January 2019 July 2020, five patients chronic diagnosed by pathological biopsy metagenomic next-generation sequencing (mNGS) were analyzed this retrospective study.Among patients,...
The aim of the reported study was to optimize extraction process for ganoderma triterpenes and investigate in vivo inhibitory effect on genesis progression oral cancer. Single-factor orthogonal methods were used effects solvent, solvent amount, time, temperature, number extractions, rate triterpenes. A golden hamster model with cheek pouch dynamic canceration established receive treatment water solution. Animals continuously monitored, tissue samples collected histopathologic examination,...
With the increasing demand for battery electric buses, dual-motor coupling powertrain (DMCP) shows great advantages, but it makes energy optimization problem more complex. To solve hybrid system problem, a stochastic model predictive control (SMPC) method is proposed to exploit potential performance of DMCP, where most critical issue improve prediction accuracy and handle uncertainties. After analyzing typical velocity profiles, statistical properties are used develop novel Signed Markov...
Methotrexate is widely used in chemotherapy for a variety of malignancies. However, severe toxicity, poor pharmacokinetics, and narrow safety margin methotrexate limit its clinical application. The aim this study was to develop sustained-release methotrexate-loaded implants evaluate antitumor activity the after intratumoral implantation.We prepared containing methotrexate, poly(D,L-lactide-co-glycolide), polyethylene glycol 4000 with melt-molding technique. were characterized regards drug...
Cancer stem-like cells (CSCs) have been reported to play major roles in tumorigenesis, tumor relapse, and metastasis after therapy against colorectal carcinoma (CRC). Therefore, identification of CSC regulators could provide promising targets for CRC. Ligand-of-Numb protein X1 (LNX1) is one E3 ubiquitin ligase which mediates the ubiquitination degradation Numb. Although several studies indicate LNX1 be a potential suppressor cancer diseases, functions mediating stemness remain poorly...
In this paper, we present a framework for convolutional coded Poisson receivers (CCPRs) that incorporates spatially coupled methods into the architecture of (CPRs). We use density evolution equations to track packet decoding process with successive interference cancellation (SIC) technique. derive outer bounds stability region CPRs when underlying channel can be modeled by $\phi$-ALOHA receiver. The is set loads every successfully received probability 1. Our extend those spatially-coupled...
Apoptosis protease activating factor-1 (Apaf-1) and death-associated protein kinase (DAPK) are p53 pathway-related genes that play significant roles in the activation of caspases, which involved mitochondrial-mediated apoptosis. The present study aimed to confirm role hyper-methylation Apaf-1 DAPK gene promoter regions oral squamous cell carcinoma (OSCC) effect demethylation drug, 5-aza-2'-deoxycytidine (DAC). mRNA from 53 OSCC samples, 23 normal mucosa samples Tca8113 human tongue lines was...
Intrusion detection techniques at the level of system processes are discussed, and a new method named V-AHD (Variable-length Average Hamming Distance) is presented, which can be used to monitor calculate deviation discriminate between normal abnormal sequences calls. For reason that fixed-length patterns not describe behavior correctly its inability represent long meaningful substrings, use Teiresias get variable-length construct set. Then algorithm for described in detail, pseudocode also...
Based on the analysis of several kinds methods generally used to intercept network packets in different layers, a dynamic mechanism using NDIS intermediate drivers is proposed protect web security, which can block malicious connection real time. The mainly composed three components include driver-based interception module, filter module and cooperation module. Characteristics every component are also introduced. Then system realization discussed detail. Finally, experiments results show that...
A rare case of fungus Arthroderma multifidum infection occurred in a 63-year-old man. The patient had some risk factors, including occupational exposure, immunosuppressive state, and structural basis following pulmonary tuberculosis pneumothorax surgery. pathogen was repeatedly isolated from bronchoalveolar lavage fluid identified by gene sequencing. It is the first report human caused A. multifidum. Whole genome sequencing analysis its genomic characterization are completed. findings...