- Cardiovascular Health and Risk Factors
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis B Virus Studies
- Adipose Tissue and Metabolism
- Nutrition, Health and Food Behavior
- Asthma and respiratory diseases
- Sirtuins and Resveratrol in Medicine
- Cholangiocarcinoma and Gallbladder Cancer Studies
- RNA modifications and cancer
- Autophagy in Disease and Therapy
- Ferroptosis and cancer prognosis
- Lung Cancer Treatments and Mutations
- Cancer, Lipids, and Metabolism
- Nutrition, Genetics, and Disease
- Pancreatic and Hepatic Oncology Research
- Climate Change and Health Impacts
- Thermoregulation and physiological responses
Peking University
2022-2024
Nanjing Medical University
2024
Nanchang University
2023
The effects of temperature and relative humidity on different types children's allergic diseases have not been comprehensively evaluated so far. This study aims to assess the impact variability identify critical time window. We collected outpatient data allergen testing in children between July 2020 January 2022 from Affiliated Children's Hospital Nanjing Medical University. defined 1st, 10th, 90th, 99th percentiles as extreme cold, moderate hot, hot for temperature, low, high, high...
Scope Apigenin (AP) has many pharmacological activities, including anti‐inflammation, hyperlipidemia‐lowering, and so on. Previous studies show that AP can reduce lipid accumulation in adipocytes vitro. However, it remains unclear whether how promote fat‐browning. Therefore, mouse obesity model preadipocyte induction vitro are used to investigate the effects of on glycolipid metabolism, browning autophagy as well possible mechanisms. Methods results The obese mice intragastrically...
We explore the dose-efficacy relationship of lenvatinib plus anti-PD-1 in patients with unresectable hepatocellular carcinoma (u-HCC) infected hepatitis B virus (HBV) real-world practice. Furthermore, we identify population sensitive to treatments.This retrospective study included 70 treated at least 3 cycles and 140 alone. Stabilized inverse probability treatment weighting (SIPTW) was used balance clinical features between two groups. The overall survival (OS), progression-free (PFS),...
Introduction Dysregulation in lipid metabolism contributes to the occurrence and development of various cancers. The relationship between changes intrahepatic cholangiocarcinoma (ICC) pathogenesis is yet unclear. We aimed explore role serum levels ICC patients that underwent surgery.Methods retrospectively enrolled 97 surgery. After 92.2 months follow-up, Kaplan-Meier analysis Cox proportional hazard model were used calculate overall survival (OS) recurrence-free (RFS).Results median age...
Objective: To describe the distribution characteristics of type 2 diabetes in twins Chinese National Twin Registry (CNTR), provide clues and evidence for revealing influence genetic environmental factors diabetes. Methods: Of all registered CNTR during 2010-2018, a total 18 855 twin pairs aged ≥30 years with complete registration information were included analysis. The random effect model was used to population area concordance pairs. Results: mean age subjects (42.8±10.2) years, study 10...
e16152 Background: To assess the efficacy and safety of lenvatinib plus anti-PD-1 versus alone in patients with unresectable hepatocellular carcinoma (u-HCC) explore characteristics benefit population for combination therapy. Methods: This retrospective study included 70 u-HCC that were treated 140 Fifth Medical Center Chinese PLA General Hospital Electric Power Beijing from November 2017 to February 2021. Clinical features balanced by stabilized inverse probability treatment weighting...
Objective: To describe the distribution characteristics of coronary heart disease in adult twins recruited from Chinese Twin Registry (CNTR), and provide clues evidence for effect genetic environmental influences on disease. Methods: By using data CNTR during 2010-2018, a total 34 583 twin pairs aged ≥18 years who completed questionnaire survey had related information were included current study to analyze population area Random models used compare differences between groups. The concordane...
Objective: To describe the distribution characteristics of tea consumption in adult twins recruited Chinese National Twin Registry (CNTR) and provide clues to genetic environmental influences on consumption. Methods: Enrolled CNTR during 2010-2018, 25 264 twin pairs aged 18 years above were included subsequent analysis. Random effect models used estimate population regional characteristics. The concordance rate behavior difference volume within also described. Results: mean age all subjects...