A5046127285- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
- Nanoparticle-Based Drug Delivery
- Periodontal Regeneration and Treatments
- Dental Radiography and Imaging
- Dental Implant Techniques and Outcomes
- Luminescence and Fluorescent Materials
- Aquaculture disease management and microbiota
- Advanced biosensing and bioanalysis techniques
- Mass Spectrometry Techniques and Applications
- Aquaculture Nutrition and Growth
- Composting and Vermicomposting Techniques
- Biofuel production and bioconversion
- RNA Interference and Gene Delivery
- Cancer Research and Treatments
- Cancer, Hypoxia, and Metabolism
- Immunotherapy and Immune Responses
- Physiological and biochemical adaptations
- Advanced Chemical Physics Studies
- Advanced Drug Delivery Systems
- Analytical Chemistry and Chromatography
- Advanced Nanomaterials in Catalysis
- Oral microbiology and periodontitis research
- Traditional Chinese Medicine Analysis
- Molecular Sensors and Ion Detection
Qingdao University
2018-2025
Shanghai Ocean University
2020-2025
Ministry of Agriculture and Rural Affairs
2022-2025
Tianjin Medical University General Hospital
2025
Anhui Agricultural University
2025
Shanxi Medical University
2010-2025
Nanjing Institute of Agricultural Mechanization
2018-2024
Southeast University
2022-2024
Central Hospital of Putuo District
2023
Peking University
2005-2022
Abstract Photodynamic therapy (PDT) is an emerging technology for tumor treatment in which photosensitizer (PS)-mediated light irradiation reduces oxygen, producing high levels of reactive oxygen species (ROS) that can cause vascular injury and effectively kill cells. However, the naturally hypoxic microenvironment main obstacle hinders photodynamic response vivo prevents its extensive application to treatment. Moreover, PDT-mediated consumption further increases hypoxia, potentially causing...
Rheumatoid arthritis (RA) is a common chronic systemic autoimmune disease that often results in irreversible joint erosion and disability. Methotrexate (MTX) the first-line drug against RA, but significant side effects of long-term administration limit its use. Therefore, new therapeutic strategies are needed for treating RA. Here, dual-targeting biomimetic carrier-free nanomaterials (BSA-MTX-CyI nanosystem, BMC) developed synergistic photo-chemotherapy Bovine serum albumin (BSA), which has...
Phototheranostics, which combines deep tissue imaging and phototherapy [photodynamic therapy (PDT) and/or photothermal (PTT)] via light irradiation, is a promising strategy to treat tumors. Near-infrared (NIR) cyanine dyes are researched as potential phototheranostics reagents for their excellent photophysical properties. However, the low singlet oxygen generation efficiency of often leads inadequate therapeutic efficacy Herein, we modified an indocyanine green derivative Cy7 with heavy atom...
Photodynamic therapy (PDT) is a promising strategy in cancer treatment that utilizes photosensitizers (PSs) to produce reactive oxygen species (ROS) and eliminate cells under specific wavelength light irradiation. However, special tumor environments, such as those with overexpression of glutathione (GSH), which will consume PDT-mediated ROS, well hypoxia the microenvironment (TME) could lead ineffective treatment. Moreover, PDT highly light-dependent therefore can be hindered deep where...
Microfluidics-mediated NDDS show uniform morphology, size and distribution, reduced batch-to-batch variations controllable drug delivering capacity.
<sup>LY</sup>iCluster<sub>siPD-L1</sub> could deliver LY2157299 to PSCs and release PAMAM/si<italic>PD-L1</italic> penetrate into tumors target tumor cells. On synergistic therapy of both, enhanced CD8<sup>+</sup> T cell infiltration cytotoxicity were expected.
Abstract Background In the last decade, graphene oxide-based nanomaterials, such as oxide (GO) and reduced (rGO), have attracted more attention in field of biomedicine. Due to versatile surface functionalization, ultra-high area, excellent biocompatibility which hold better promise for potential applications than among other nanomaterials biomedical fields including drug/gene delivery, biomolecules detection, tissue engineering, especially cancer treatment. Results Here, we review recent...
Patients treated with Pt-based anticancer drugs (Pt
Abstract Background Glycine powder air‐polishing ( GPAP ) has the potential to effectively erase biofilms and may improve treatment efficacy of peri‐implant mucositis. This pilot clinical trial evaluated effect as an adjunct in treating Materials methods Twenty‐four subjects having at least one implant with mucositis were randomly assigned test (12 17 implants) control 16 groups. Following baseline assessment, all received oral hygiene instruction non‐surgical debridement. In group, sites...
Rationale: Dental implant restoration is essential for rehabilitating dentition defects. However, peri-implantitis (PI) seriously threatens the long-term stability of implants. Treating PI requires complete eradication plaque biofilm and meticulous modulation inflammatory responses. Antibacterial photodynamic therapy (aPDT) presents a promising potential in antibacterial realm. Nonetheless, traditional aPDT faces challenges such as inadequate penetration distribution photosensitizers, well...
Cryptotanshinone (CTS), a major constituent from the roots of Salvia miltiorrhiza (Danshen), is widely used in treatment coronary heart disease, stroke and less commonly Alzheimers disease. Our recent study indicates that CTS substrate for Pglycoprotein (PgP/MDR1/ABCB1). This has investigated nature brain distribution across brain-blood barrier (BBB) using several vitro vivo rodent models. A polarized transport was found rat primary microvascular endothelial cell (RBMVEC) monolayers, with...