A5015096848- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Sarcoma Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Genetic factors in colorectal cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lung Cancer Research Studies
- Neuroblastoma Research and Treatments
- Plant responses to water stress
- Colorectal and Anal Carcinomas
- Gastrointestinal Tumor Research and Treatment
- Cancer Immunotherapy and Biomarkers
- Behavioral Health and Interventions
- Rice Cultivation and Yield Improvement
- Cancer Genomics and Diagnostics
- Esophageal Cancer Research and Treatment
- Nanocomposite Films for Food Packaging
- GABA and Rice Research
- Plant Pathogenic Bacteria Studies
- Plant Disease Management Techniques
- Cancer Diagnosis and Treatment
- Impact of Technology on Adolescents
- Colorectal Cancer Screening and Detection
- Lymphoma Diagnosis and Treatment
- Antimicrobial agents and applications
University of Southampton
2024-2025
Identity
2025
Huazhong Agricultural University
2019-2023
Sun Yat-sen University
2009-2023
Sun Yat-sen University Cancer Center
2009-2023
State Key Laboratory of Oncology in South China
2009-2022
Sichuan University
2022
Shanghai Zhangjiang Laboratory
2021
Abstract Lymph node (LN) metastasis is known as one of the most important prognostic factors for early gastric cancer (EGC) patients. Patients without LNM normally have better prognosis. However, there no evaluation criteria to accurately assess possibility LN metastasis. Therefore, this study aims establish an effective nomogram prognosis prediction. In study, 285 EGC patients from January 2010 December 2015 were enrolled. Pearson’s Chi-Square ( χ 2 ) test (including continuity correction...
The reward responsivity hypothesis of self-control proposes that irrespective success, exercising is aversive and engenders negative affect. To countermand this discomfort, reward-seeking behavior may be amplified after bouts self-control, bringing individuals back to a mildly positive baseline state. Previous studies indicated effort-an integral component self-control-can increase responsivity. We sought test extend the by asking if increases neural marker [Reward Positivity (RewP)]...
Early diagnosis and intervention are essential for improving the prognosis survival of gastric cancer (GC) patients. However, specific biomarkers early GC still unavailable. Data-independent acquisition (DIA) proteomics was employed to identify differentially expressed proteins (DEPs) between adjacent non-tumor tissues. Functional pathway enrichment analyses were conducted, with subsequent genomic-level validation. Methyltransferase-like 7A (METTL7A) expression in versus tissues confirmed...
Background: Preoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) are associated with poor prognosis in soft tissue sarcoma (STS).The aim of the present study is to determine whether combination NLR PLR (CNP) can better predict patient survival after resection for STS.Methods: We included 310 STS patients this retrospective study.Preoperative CNP was calculated as follows: both elevated (>2.51) (>191.1)were given a score 2; showing an increase one or neither were...
Huanghuazhan (HHZ) and 9,311 are two elite rice cultivars in China. They have achieved high yield through quite different mechanisms. One of the major features that gives capacity to is its strong early vigor, i.e., faster establishment seedling as well better growth stages. To understand mechanistic basis vigor 9,311, compared HHZ cultivar, we examined, under controlled environmental conditions, morphological physiological traits may contribute vigor. Our results show fresh weight seeds, at...
Importance The E-cadherin gene, CDH1 , and the α-E-catenin CTNNA1 were previously identified as hereditary diffuse gastric cancer (HDGC) susceptibility genes, explaining 25% to 50% of HDGC cases. genetic basis underlying disease in remaining 75% patients with is still unknown. Objective To assess incidence rate germline alterations HDGC, identify new genes that can be used for screening provide a landscape HDGC. Design, Setting, Participants This cohort study conducted retrospective...
The widespread escalation of bacterial resistance threatens the safety food chain. To investigate characteristics
The aim of this longitudinal study was to try and improve the specificity carcinoembryonic antigen (CEA) carbohydrate (CA) 19-9 in monitoring tumor recurrence patients with resectable gastric adenocarcinoma by setting suitable elevation levels.One hundred eighty-one were considered. Serum samples obtained preoperatively every 3 months postoperatively.Preoperative CEA CA19-9 positivity rates 19.9% 18.2%. sensitivity monitor 92.9% 23.4% versus 76.5% 78.9% CEA-negative CEA-positive patients,...
The healing of grafted seedlings is to complete the process callus induction, differentiation and union stock scion. This stage important ensure survival seedlings, especially for scion since roots will be removed in vast majority grafting. does not form same type organization with rootstock. two conducting tissues are uniformly connected; thus, rootstock do transport water nutrients through roots. To prevent this problem, suitable relative humidity temperature must provided wilt properly...
Currently, pre-treatment prediction of patients with pancreatic neuroendocrine tumors liver metastases (PNELM) receiving surufatinib treatment was unsatisfying. Our objective to examine the association between radiological characteristics and efficacy/prognosis.We enrolled in phase III, SANET-p trial (NCT02589821) obtained contrast-enhanced computed tomography (CECT) images. Qualitative quantitative parameters including hepatic tumor margins, lesion volumes, enhancement pattern, localization...
Abstract Background Tumour immune microenvironment heterogeneity is prevalent in numerous cancers and can negatively impact immunotherapy response. Immune evolution gastroesophageal adenocarcinoma (GEA) have not been studied the past. Methods Together with a multi-region sampling of normal, primary metastatic tissues, we performed whole exome sequencing, TCR sequencing as well cell infiltration estimation through deconvolution gene expression signals. Results We discovered high repertoire...
11513 Background: GIST is a rare mesenchymal tumor whose management has been transformed by approvals of TKIs. However, treatment resistance formidable challenge in managing locally advanced or metastatic GIST. Pts with SDH-deficient are not sensitive to imatinib and other TKIs, frequently multifocal, typically have multinodular architecture. Olverembatinib novel, potent, orally active third-generation TKI promising activity against multiple preclinical models. Methods: The aim this phase...
ABSTRACT Bananas ( Musa spp.) are one of the most important tropical fruits and staple food, which great significance to human societies. Plantain Silk two banana subgroups, both triploid hybrids (AAB) between wild diploid acuminata M. balbisiana . In this study, we reported first haplotype-resolved genome assembly bananas with size approximately 1.4 Gb. We discovered widespread asymmetric evolution in subgenomes Silk, could be linked frequent homologous exchanges (HEs) events. This is study...
Abstract Existing literature shows a link between future temporal focus (FTF) and smartphone addiction (SA). However, the precise psychological mechanisms underlying this relationship remain inadequately explored, despite recognized importance of meaning in life (MIL) self-control (SC) influencing FTF-SA correlation. This study seeks to elucidate mediating roles MIL SC within relationship. A total 462 university students ( M age = 19.57, SD 1.09) participated study, completing scales for...
4054 Background: Circulating tumor DNA (ctDNA) is a promising biomarker for detecting molecular residual disease (MRD) and relapse after definitive treatment in multiple solid cancers. However, the significance of ctDNA rarely clarified locoregional gastric cancer (GC). Here, we conducted prospective observational study to evaluate utility predicting recurrence risk GC. Methods: From October 2016 June 2019, 100 patients with stage II/III resectable GC were recruited this (NCT02887612)....
Abstract Background: The relationship between gastric bare area adipose tissues invasion (GBAI) confirmed pathologically and the prognosis of cancer (GC) patients is undefined. Till present, there hasn’t been literature investigating this phenomenon. Here, we aimed at analyzing implication GBAI in GC. Methods: data 1822 who underwent radical surgery January 2000 December 2013 Sun Yat-sen University Cancer Center were retrieved. Pathologically, tumor deposits (TDs) located >5mm from...
Abstract Background: The relationship between gastric bare area adipose tissues invasion (GBAI) confirmed pathologically and the prognosis of cancer (GC) patients is undefined. Till present, there hasn’t been literature investigating this phenomenon. Here, we aimed at analyzing implication GBAI in GC. Methods: data 1822 who underwent radical surgery January 2000 December 2013 Sun Yat-sen University Cancer Center were retrieved. Pathologically, tumor deposits (TDs) located >5mm from...
4126 Background: Surufatinib is a small-molecule inhibitor of VEGFR1, 2, & 3, FGFR1, and CSF-1R. demonstrated prolonged PFS tolerable safety in two phase 3 studies advanced neuroendocrine tumors (NETs) pancreatic (SANET-p; NCT02589821) extrapancreatic (SANET-ep; NCT02588170) origin (Xu, 2020 Lancet Oncology). Detailed outcomes on from these 2 are reported here as pooled analysis. Methods: Data SANET-p SANET-ep which have similar designs including 2:1 randomization surufatinib to placebo...
e21511 Background: There remain unmet needs to identify novel immune checkpoint inhibitors improve the benefit-risk profile of immunotherapy for advanced melanoma. The comparison between LAG3-PD1 inhibition and CTLA4-PD1 was lacked. To compare lymphocyte-activation gene 3 (LAG3) plus programmed cell death 1 (PD-1) versus cytotoxic T-lymphocyte antigen 4 (CTLA-4) PD-1 in patients with previously untreated Methods: individual participant data (IPD) were extracted from KM plots using a...