A5081816513- Inflammatory Bowel Disease
- Immunodeficiency and Autoimmune Disorders
- Helicobacter pylori-related gastroenterology studies
- Acute Lymphoblastic Leukemia research
- Cytomegalovirus and herpesvirus research
- Autoimmune Bullous Skin Diseases
- Platelet Disorders and Treatments
- Viral gastroenteritis research and epidemiology
- Pregnancy and Medication Impact
- Reproductive System and Pregnancy
- Viral Infections and Immunology Research
Juntendo University
2020-2025
National Center For Child Health and Development
2024
Abstract Background Very-early-onset ulcerative colitis (VEO-UC) is a severe form of inflammatory bowel disease that manifests before the age 6 years. Compared to typical pediatric UC, it characterized by distinct genetic and immunological factors. This study aimed investigate roles specific human leukocyte antigen (HLA) alleles maternal microchimerism (MMc) in pathogenesis VEO-UC Japanese population. Methods included 27 patients, including 4 patients treated with colorectal resection. HLA...
Abstract Background and Aim Only a few studies have reported the long‐term effects of ustekinumab on pediatric Crohn's disease. Therefore, this study aimed to describe clinical endoscopic outcomes its safety profile in pediatric‐onset disease with anti‐tumor necrosis factor failure. Methods Medical records patients whom therapy failed treatment was initiated from 2017 2022 at Japanese tertiary children's hospital were retrospectively reviewed. The primary outcome continuation rates weeks 8,...