A5064149124- Reproductive Biology and Fertility
- SARS-CoV-2 and COVID-19 Research
- Immunotherapy and Immune Responses
- Reproductive Physiology in Livestock
- Bacillus and Francisella bacterial research
- Glycosylation and Glycoproteins Research
- Assisted Reproductive Technology and Twin Pregnancy
- RNA and protein synthesis mechanisms
- DNA and Biological Computing
- Monoclonal and Polyclonal Antibodies Research
- CAR-T cell therapy research
- Advanced biosensing and bioanalysis techniques
- Myasthenia Gravis and Thymoma
- Genetic and phenotypic traits in livestock
- Advanced Biosensing Techniques and Applications
- Uterine Myomas and Treatments
- Biomedical Ethics and Regulation
- Endometriosis Research and Treatment
Seoul National University
2021-2024
The immune escape of Omicron variants significantly subsides by the third dose an mRNA vaccine. However, it is unclear how variant-neutralizing antibodies develop under repeated vaccination. We analyze blood samples from 41 BNT162b2 vaccinees following course three injections and their B-cell receptor (BCR) repertoires at six time points in total. concomitant reactivity to both ancestral receptor-binding domain (RBD) achieved a limited number BCR clonotypes depending on accumulation somatic...
Myasthenia Gravis (MG) patients with anti-acetylcholine receptor (AChR) antibodies frequently show hyperplastic thymi ectopic germinal centers, where autoreactive B cells proliferate the aid of T cells. In this study, thymus and peripheral blood (PB) samples were collected from ten AChR antibody-positive MG patients. cell (TCR) repertoires analyzed using next-generation sequencing (NGS), compared that an age sex matched control group generated a public database. Certain V genes VJ gene...
The immune escape of Omicron variants significantly subsides by the third dose an mRNA vaccine. However, it is unclear how variant-neutralizing antibodies develop under repeated vaccination. We analyzed blood samples from 41 BNT162b2 vaccinees following course three injections and their B-cell receptor (BCR) repertoires at six time points in total. concomitant reactivity to both ancestral receptor-binding domain (RBD) was achieved a limited number BCR clonotypes depending on accumulation...