Adeline Renuy
A5082146833- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Alcohol Consumption and Health Effects
- COVID-19 Clinical Research Studies
- Liver Disease Diagnosis and Treatment
- COVID-19 epidemiological studies
- SARS-CoV-2 detection and testing
- COVID-19 and Mental Health
- Nutritional Studies and Diet
- Liver Disease and Transplantation
- Asthma and respiratory diseases
- Employment and Welfare Studies
- Obesity, Physical Activity, Diet
- Sleep and related disorders
- Workplace Health and Well-being
- Allergic Rhinitis and Sensitization
- Substance Abuse Treatment and Outcomes
- Physical Activity and Health
- Pediatric health and respiratory diseases
- Health, Medicine and Society
- Vitamin D Research Studies
- Dementia and Cognitive Impairment Research
- Obstructive Sleep Apnea Research
- Oral Health Pathology and Treatment
- Data-Driven Disease Surveillance
Université Paris Cité
2021-2025
Inserm
2019-2025
Université Paris-Saclay
2020-2025
Université de Versailles Saint-Quentin-en-Yvelines
2020-2025
Sorbonne Paris Cité
2025
Centre de recherche en Epidémiologie et Santé des Populations
2019-2024
Cohortes épidémiologiques en population
2021-2024
Hôpital Paul-Brousse
2021-2024
Institut National de Santé Publique
2021
Santé Publique France
2021
After an infection by SARS-CoV-2, many patients present with persistent physical symptoms that may impair their quality of life. Beliefs regarding the causes these influence perception and promote maladaptive health behaviors.
The severity of liver injury and clinical outcomes in lean individuals with NAFLD is a subject debate very few studies have been performed the general population. aim this study was to compare characteristics mortality between nonlean community setting.The population included 169,303 participants from nationwide Constances cohort. Subjects excessive alcohol consumption, viral hepatitis, or other diseases were excluded 137,206 subjects analyzed. diagnosis fibrosis using Fatty Liver Index...
We aimed to estimate the seropositivity anti-SARS-CoV-2 antibodies in May-June 2020 after first lockdown period adults living three regions France and identify associated risk factors.
Abstract Background To estimate the seroprevalence of SARS-CoV-2 infection in May-June 2020 after lockdown adults living three regions France and to identify associated risk factors. Methods Participants a survey on COVID-19 from an existing consortium general adult population cohorts Ile-de-France (IDF) or Grand Est (GE) - two with high rate COVID-19, Nouvelle-Aquitaine (NA) – low rate, were asked take dried-blood spot (DBS) for anti-SARS-CoV-2 antibodies assessment. The primary outcome was...
Importance Persistent symptoms after SARS-CoV-2 infection are an emerging public health problem. The duration of these remains poorly documented. Objective To describe the temporal dynamics persistent and factors associated with their resolution. Design, Setting, Participants This cross-sectional study involved 53 047 participants from 3 French adult population-based cohorts (CONSTANCES [Consultants des Centres d’Examens de Santé], E3N/E4N, Nutrinet-Santé) who were included in a nationwide...
Background Obstructive sleep apnoea (OSA) is associated with increased morbidity and mortality. Although the disorder has been well studied in selected high-risk populations, few data exist on its prevalence general population. We aimed to assess determinants of OSA France. Methods Data from participants French population-based CONSTANCES cohort aged 18–69 years at inclusion being treated for or screened 2017 using Berlin Questionnaire were analysed. Weighted analyses performed provide...
Abstract Aim To assess the prevalence of severe periodontitis based on population‐based CONSTANCES cohort using a validated self‐reported questionnaire. Materials and Methods Individuals were selected from adult population in France random sampling scheme. Analyses restricted to those invited 2013–2014 who completed periodontal health questionnaire at 2017 follow‐up. The risk was assessed screening score (PESS) weighting coefficients applied provide representative results general French...
Data are lacking regarding the prevalence of benzodiazepine long-term use in general population. Our aim was to examine prescribed (BLTU) according sociodemographic and clinical factors French came from 4686 men 4849 women included 2015 population-based CONSTANCES cohort. BLTU examined using drug reimbursement administrative registries 2009 2015. Analyses were weighted provide results representative population covered by health insurance scheme. Weighted BTLU Odds Ratios (OR) having computed...
Abstract This study provides trends in obesity prevalence adults from 2013 to 2016 France. 63,582 men and women independent samples upon inclusion the Constances cohort were included. Anthropometrics measured at Health Screening Centers defined as a Body mass index (BMI) ≥ 30 kg/m 2 ; classes according BMI are follows: class 1 [30–34.9]; [35–39.9]; 3 [≥ 40 ]. Linear across by sex age groups examined regression models percentage point change for each category calculated. All analyses...
Nutritional factors are essential for the functioning of immune system and could therefore play a role in COVID-19 but evidence is needed. Our objective was to study associations between diet risk SARS-CoV-2 infection large population-based sample.Our analyses were conducted French prospective NutriNet-Santé cohort (2009-2020). Seroprevalence anti-SARS-CoV-2 antibodies assessed by ELISA on dried blood spots. Dietary intakes derived from repeated 24 h dietary records (at least 6) two years...
Background Scarce epidemiological studies have characterised allergic rhinitis (AR) and non-allergic (NAR) in adults. In a population-based cohort, our aims were to 1) describe rhinitis, AR NAR, 2) explore how asthma conjunctivitis may lead the identification of novel phenotypes. Methods this cross-sectional analysis, current was defined as present last 12 months using questionnaire from French CONSTANCES cohort. Participants with reporting nasal allergies considered AR, otherwise NAR. We...
The impact of non-alcoholic fatty liver disease (NAFLD) on morbidity and mortality has yet to be documented at the general population level. This study aimed assess whether NAFLD was associated with morbidities estimate its health status mortality.The consisted 137 206 participants from Constances cohort. Non-invasive diagnosis advanced fibrosis performed using index Forns index, respectively. data were linked care hospitalization identify liver-related events, cardiovascular diseases (CVD),...
Background: To estimate the seroprevalence of SARS-CoV-2 infection in May-June 2020 after lockdown adults living three regions France and to identify associated risk factors.Methods: Participants a survey on COVID-19 from an existing consortia general adult population cohorts Ile-de-France (IDF) or Grand Est (GE) - two with high rate COVID-19, Nouvelle-Aquitaine (NA) – low rate, were asked take dried-blood spot (DBS) for anti-SARS-CoV-2 antibodies.The primary outcome was positive ELISA IgG...
The individual results of SARS-CoV-2 serological tests measured after the first pandemic wave 2020 cannot be directly interpreted as a probability having been infected. Plus, these are usually returned binary or ternary variable, relying on predefined cut-offs. We propose Bayesian mixture model to estimate infection probabilities, based 81,797 continuous anti-spike IgG from Euroimmun collected in France wave. This approach used and was therefore not diagnostic Cumulative incidence, which is...
Objectives Uncertainty exists as to what extent common risk factors are involved in the associations of unemployment with major health outcomes and mortality. Design A retrospective prospective observational study. Setting large population-based French cohort (CONSTANCES). Participants 99 430 adults at baseline who have been exposed during their lifetime 54 679 them were followed for 7 years after baseline. Primary outcome measures Testing mediating roles several exposure cardiovascular...
Abstract ABO blood type has been reported as a potential factor influencing SARS-CoV-2 infection, but so far mostly in studies that involved small samples, selected population and/or used PCR test results. In contrast our study aimed to assess the association between types and infection using seroprevalence data (independent of whether or not individuals had symptoms sought for testing) large population-based sample. Our included 67,340 French participants SAPRIS-SERO multi-cohort project....
Objective: To estimate the proportion of participants French national population-based CONSTANCES cohort exceeding new low-risk drinking guidelines according to sociodemographic and clinical factors. Methods: From 34,470 with follow-up data in 2019, among volunteers aged 18–69 years invited enroll 2016 2017, weighted prevalence odds ratios 95% confidence intervals (CI) using logistic regressions were presented stratified for age, gender, education, occupational grade, employment, income,...
Abstract Background The interplay between age and symptoms intensity on antibody response to SARS-CoV-2 infection has not been studied in a general population setting. Methods We explored the serologic profile of anti-SARS-CoV-2 antibodies after first wave pandemic, by assessing IgG against spike protein (ELISA-S), nucleocapsid (ELISA-NP) neutralizing (SN) 82,126 adults from French population-based multi-cohort study. Results ELISA-S positivity was increased 30- 49-year-old (8.5%) compared...
Assessment of the intensity, dynamics and determinants antibody response after SARS-CoV-2 infection or vaccination in general population is critical to guide policies. This study characterized anti-spike IgG titers 13,971 participants included a French multicohort population-based serological survey on COVID-19 between April October 2020 followed-up with testing May 2021. Eight follow-up profiles were defined depending (0, 1 2) 1, 2 3). The titer was lower adults no even case reinfection,...
Abstract Lockdown imposed in the early phase of SARS-CoV-2 outbreak represented a specific setting where activity was restricted but still possible. The aim to investigate cross-sectional associations between physical (PA) and infection French population-based cohort. Participants completed PA questionnaire. classified into: ( i ) total PA; ii aerobic by intensity; iii strengthening iv domain type; vii location. Sedentary time also recorded. Seroprevalence anti-SARS-CoV-2 antibodies...
Walking speed (WS) represents an objective measure of motor function and health. We aimed to develop usual (UWS) fast WS (FWS) norms for the general population using a regression-based approach, while considering age, sex, height, education.