Nisha Mathews
- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Vasculitis and related conditions
- Parathyroid Disorders and Treatments
- Dialysis and Renal Disease Management
- Electrolyte and hormonal disorders
- Genetic Syndromes and Imprinting
- Muscle and Compartmental Disorders
- Biomedical Research and Pathophysiology
- COVID-19 Clinical Research Studies
- Pregnancy and Medication Impact
- SARS-CoV-2 and COVID-19 Research
- Platelet Disorders and Treatments
- Clinical Nutrition and Gastroenterology
- Healthcare Policy and Management
- Renal Transplantation Outcomes and Treatments
- Ovarian cancer diagnosis and treatment
- Fibroblast Growth Factor Research
University of Oklahoma Health Sciences Center
2020
The University of Texas Southwestern Medical Center
2013-2015
Children's Medical Center
2015
Fibroblast growth factor 23 (FGF23) is a bone-derived hormone that acts on the proximal tubule to decrease phosphate reabsorption and serum levels of 1,25-dihydroxyvitamin D₃ [1,25(OH)₂ Vitamin D₃]. Abnormal FGF23 metabolism has been implicated in several debilitating hypophosphatemic hyperphosphatemic disorders. The renal receptors responsible for phosphaturic actions have not elucidated. There are four fibroblast (FGFR); 1-4 with "b" "c" isoforms 1, 2, 3. FGFR1, 3, 4 expressed mouse...
Prior cross-sectional studies suggest that health-related quality of life (HRQOL) worsens with more severe glomerular disease. This longitudinal analysis was conducted to assess changes in HRQOL changing disease status.Cure Glomerulonephropathy (CureGN) is a cohort patients minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, IgA vasculitis, or nephropathy. assessed at enrollment and follow-up visits 1 3 times annually for up 5 years the Patient-Reported...
The incidence of end stage renal disease (ESRD) in US children age 0-19 years is 12.9 per million/year (2012). economic and social burden diagnosing, treating preventing chronic kidney (CKD) adults remains substantial. Advances identifying factors that predict development CKD its progression, as well advances the management co-morbid conditions including anemia, cardiovascular disease, growth, mineral bone disorder, neurocognitive function are discussed. Despite recent reports from...
Glomerular diseases are characterized by variable disease activity over many years. We aimed to analyze the relationship between clinical and duration of glomerular disease.Disease in adults with chronic minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, IgA nephropathy (IgAN; first diagnostic biopsy >5 years before enrollment; Of Longstanding Disease [OLD] cohort, n = 256) followed at Columbia University Medical Center (CUMC), was compared an internal...