George Mutema

ORCID: 0009-0006-9736-0222
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About
Contact & Profiles
Research Areas
  • Health Systems, Economic Evaluations, Quality of Life
  • Advanced Causal Inference Techniques
  • Pelvic floor disorders treatments
  • Science, Research, and Medicine
  • Prostate Cancer Treatment and Research
  • Global Public Health Policies and Epidemiology
  • Prostate Cancer Diagnosis and Treatment
  • Genetic Associations and Epidemiology
  • Vaccine Coverage and Hesitancy
  • Insurance, Mortality, Demography, Risk Management
  • Multiple and Secondary Primary Cancers
  • Sexual function and dysfunction studies
  • Anorectal Disease Treatments and Outcomes
  • Neurofibromatosis and Schwannoma Cases
  • Full-Duplex Wireless Communications
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Colorectal Cancer Screening and Detection
  • Molecular Biology Techniques and Applications
  • Polyomavirus and related diseases
  • Ethics in Clinical Research
  • Soft tissue tumors and treatment
  • Urinary Bladder and Prostate Research
  • Bone Tumor Diagnosis and Treatments
  • Neuroendocrine Tumor Research Advances
  • HIV/AIDS Impact and Responses

John Wiley & Sons (United States)
2018

Hudson Institute
2018

Good Samaritan Hospital
2004-2017

Good Samaritan Regional Medical Center
2017

Good Samaritan Medical Center
2017

TriHealth
2016-2017

Legacy Good Samaritan Medical Center
2017

Good Samaritan Hospital Medical Center
2017

Good Samaritan Hospital
2016

University of Johannesburg
2011

Vaginal and urethral histology is important to understanding the pathophysiology of pelvic floor.En bloc removal 4 female cadaveric pelvises was performed, with 18 25 serial sections obtained from each. The vaginal lengths were divided into distal proximal sections; urethra anterior posterior segments as well. Innervation vasculature qualified small large quantified per high-power field.The mean length 7.45 cm, 3.38 cm. A distinct fibromuscular layer noted, without evidence a dense sheet...

10.1097/spv.0000000000000387 article EN Female Pelvic Medicine & Reconstructive Surgery 2017-01-24

Background Men of African‐ancestry have elevated prostate cancer (PCa) incidence and mortality compared to men other racial groups. There is support for a genetic contribution this disparity, with evidence heterogeneity in the underlying risk alleles between populations. Studies PCa among African may inform factors disease burden population. Methods We conducted an association study >100 previously reported 571 cases 485 controls Uganda men. Unconditional logistic regression was used test...

10.1002/pros.23481 article EN The Prostate 2018-01-21

We report a case of 79-year-old Caucasian male who presented with wrist lesion combined intraepidermal Merkel cell carcinoma and squamous in-situ. The two tumors were tightly admixed distinct, both without any dermal or invasive components. No features transition between the seen. suggest term in situ for that demonstrate exclusive proliferation neuroendocrine cells.

10.1097/00000372-200406000-00012 article EN American Journal of Dermatopathology 2004-05-11

In Brief Objective This study aimed to evaluate the histologic and cytologic effects of preoperative vaginal estrogen in women with atrophic vaginitis pelvic organ prolapse. Methods Forty-two stage greater than or equal 2 prolapse were enrolled this assessor-blinded randomized controlled trial comparing daily cream use for 12 weeks preoperatively versus no intervention. Data analyzed using t test analysis variance. Results Of these 42 women, 22 received treatment 20 controls. After a mean 7...

10.1097/spv.0b013e318278cc40 article EN Female Pelvic Medicine & Reconstructive Surgery 2013-01-01

Abstract A 57-year-old woman presented with a 2-year history of palpable mass in the upper inner quadrant right breast. 1.1-cm, poorly circumscribed, firm tumor nodule was noted, consisting 2 histologically distinct lesions same location, some areas showing purely well-differentiated invasive ductal carcinoma and others composed granular cell tumor. In 1 area, tumors collided infiltrated each other. The admixed situ solid cribriform types. To our knowledge, this is first case report...

10.5858/2002-126-0731-cgctai article EN Archives of Pathology & Laboratory Medicine 2002-06-01

Magmas is a protein that involved in GM-CSF signaling myeloid cell line. Its precise role the signal transduction process unclear. To accurately characterize expression variety of cells, mouse embryos and adult murine tissues were analyzed for both mRNA content. was detected as early day 6.5 embryo. The level developmentally regulated. During embryo-genesis, elevated observed several structures, including heart, liver, notochord, choroid plexus, cervical ganglion, nasal mucosa. Muscle,...

10.1177/002215540305100504 article EN Journal of Histochemistry & Cytochemistry 2003-05-01

Synovial sarcomas are aggressive tumors of adolescent and young adults that account for up to 10% soft tissue sarcomas. Cytogenetically, they characterized by translocation t(X;18), which is found in more than 95% tumors. In most cases, it results fusion the SYT gene with SSX1 or SSX2 gene, thus creating SYT-SSX1 SYT-SSX2 rearrangement. The 2 types have been correlated histologic variants prognosis synovial this study, we developed a simple rapid method simultaneous detection rearrangements...

10.1007/s10024-004-8097-4 article EN Pediatric and Developmental Pathology 2005-03-01

Abstract Prostate cancer risk is influenced by rare and common germline variants. We examined the aggregate association of pathogenic/likely pathogenic/deleterious (P/LP/D) variants in ATM, BRCA2, PALB2, NBN with a polygenic score (PRS) on prostate among 1,796 cases (222 metastatic) 1,424 controls African ancestry. Relative to P/LP/D non-carriers at average genetic (33%–66% PRS), men low (0%–33%) high (66%–100%) PRS had Odds Ratios (ORs) for overall 2.08 [95% confidence interval (CI) =...

10.1158/2767-9764.crc-23-0022 article EN cc-by Cancer Research Communications 2023-11-28

Abstract Backgrouns : Since its initial discovery in the avian intestine, calbindin‐D 28k has been reported to occur various species and tissues. Although binds calcium ions physiologically relevant range of intracellular calcium, functional role cell types where it localized remains unknown. Methods We examined occurrence brain kidney testudine reptile, Trachemys scripta , by immunoblotting immunocytochemistry using rabbit anti‐sera directed against rat renal chicken intestinal . Results...

10.1002/ar.1092390209 article EN The Anatomical Record 1994-06-01

Premature closure of the foramen ovale, 4-chamber cardiac hypertrophy, and renal vein/vena cava thrombosis were found at autopsy a stillborn dizygotic twin 36 weeks gestational age. Review original prenatal sonograms showed features suggestive early ovale. Homozygosity for 5,10 methylene tetrahydrofolate reductase mutation was shown only in affected after parents to be heterozygous mutation. The difference outcome twins following treatment with beta mimetics corticosteroids preterm labor may...

10.1515/jpm.2000.009 article EN Journal of Perinatal Medicine 2000-01-10

Accurate modelling of volatility is important as it relates to the forecasting Value-at-Risk (VaR). The RiskMetrics model forecast benchmark in financial sector. In an regulatory innovation, Basel Committee has proposed use internal method for VaR instead strict model. aim this paper evaluate performance comparison other models forecasting, such some family classes Generalised Auto Regressive Conditional Heteroscedasticity models, emerging markets. This makes stock market index portfolio,...

10.4102/sajems.v12i4.184 article EN cc-by South African Journal of Economic and Management Sciences 2011-04-21

Pauls, Rachel N. MD; Mutema, George K. MD, PhD; Silva, W Andre Rooney, Christopher Kleeman, Steven D. Karram, Mickey M. MD Author Information

10.1097/00006250-200604001-00245 article EN Obstetrics and Gynecology 2006-04-01
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