A5102705332- Nanoparticle-Based Drug Delivery
- RNA Interference and Gene Delivery
- Nanoplatforms for cancer theranostics
- Plant Pathogens and Fungal Diseases
- Cancer, Hypoxia, and Metabolism
- Remote Sensing in Agriculture
- Plant Water Relations and Carbon Dynamics
- Protein Interaction Studies and Fluorescence Analysis
- Soil Carbon and Nitrogen Dynamics
- Calcium signaling and nucleotide metabolism
- Ion channel regulation and function
- Adipose Tissue and Metabolism
- Proteoglycans and glycosaminoglycans research
- Renal Transplantation Outcomes and Treatments
- Mass Spectrometry Techniques and Applications
- Dendrimers and Hyperbranched Polymers
- Mitochondrial Function and Pathology
- COVID-19 Clinical Research Studies
- Saffron Plant Research Studies
- SARS-CoV-2 and COVID-19 Research
- Plant-Microbe Interactions and Immunity
- Glycosylation and Glycoproteins Research
- Enzyme Production and Characterization
- Flavonoids in Medical Research
- Advanced Drug Delivery Systems
Nankai University
2018-2025
Shanghai Academy of Environmental Sciences
2015-2025
Chuzhou University
2025
Southwest Hospital
2024
Institute of Hematology & Blood Diseases Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Nanjing Forestry University
2022-2024
Army Medical University
2024
Hangzhou Normal University
2024
The University of Melbourne
2023
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a major health threat, but the economic impact of carbapenem resistance in K. infections remains largely uninvestigated.We constructed retrospective cohort all patients hospitalized at West China Hospital 2017 who had CRKP- or carbapenem-susceptible (CSKP)-positive clinical samples. Propensity score matching (PSM) was used to control potential confounding variables, including demographics, comorbidities, and treatment, observe factors...
To ensure that anticancer drugs could be delivered to tumor region and rapidly escape from endo/lysosomes, YPSMA-1-modified pH-sensitive polymeric micelles were designed fabricated for targeted therapy of tumors.
Dual endosomal pH-sensitive micelles were designed and fabricated to deliver doxorubicin (DOX) for treating breast cancer based on a poly(2-ethyl-2-oxazoline) (PEOz)–DOX (PEOz–hyd–DOX) conjugate. PEOz–hyd–DOX was successfully synthesized by connecting DOX PEOz via an acid cleavable hydrazone linker self-assembled into nanosized micelles, which further physically encapsulated DOX. The conjugate DOX-loaded displayed faster release of at pH 5.0 than 7.4. This pH-dependent behavior might assist...
With the rise of large-scale crop plantation in China, inexpensive but efficient remote-sensing measures for predicting nitrogen status crops are needed optimal fertilizer management. In this research, a conventional digital camera with charge coupled device was integrated into an unmanned aerial vehicle (UAV) to capture images paddy rice (Oryza sativa L.) at altitude 50 m. The fluorescence emissions leaves under light excitation were used by Multiplex® non-destructively assess chlorophyll...
Abstract Immune coagulation is a major contributor to the pathogenesis of xenograft rejection, viral-induced hepatocellular injury and cytokine-induced fetal loss syndrome. In this study, we investigated contribution novel gene product, fibrinogen-like protein 2 (fgl2) prothrombinase, in mediating immune experimental human acute allograft rejection. Using mouse heterotopic cardiac transplant model, fgl2(mfgl2)/fibroleukin mRNA transcripts were highly expressed macrophages, CD4- CD8-positive...
The present study aimed to investigate the effect of monomethoxy poly(ethylene glycol)-block-poly(D,L-lactic acid) (mPEG-PLA) on activity P-glycoprotein (P-gp) in Caco-2 cells and further unravel relationship between PLA chain length mPEG-PLA influence P-gp efflux action mechanism. transport results rhodamine 123 (R123) across cell monolayers suggested that unimers were responsible for its inhibitory effect. Furthermore, studies R123 revealed potential by analogues was strongly correlated...
Proteins containing Common in Fungal Extracellular Membrane (CFEM) domains uniquely exist fungi and play significant roles their whole life history. In this study, a total of 11 MbCFEM proteins were identified from Marssonina brunnea f. sp. multigermtubi (MULT), hemibiotrophic pathogenic fungus on poplars that causes severe leaf diseases. Phylogenic analysis showed the (MbCFEM1-11) divided into three clades based trans-membrane domain CFEM domain. Sequence alignment WebLogo verified amino...
The chlorophyll meter (SPAD) has been widely used to measure the leaf N concentration. Nevertheless, linear regression equations of SPAD readings on concentration (based dry weight, Nw) differ with plant age and genotype mainly due differences in specific weight (SLW), there is a close relationship between SLW thickness. This implies that may be influenced by thickness alone. present paper testify whether rice (Oryza sativa L.) are variation different ages or genotypes. In paddy field trial...