- Chronic Kidney Disease and Diabetes
- Ginkgo biloba and Cashew Applications
- Cancer-related Molecular Pathways
- Pancreatitis Pathology and Treatment
- Kruppel-like factors research
- Vascular anomalies and interventions
- Pediatric Urology and Nephrology Studies
- Kidney Stones and Urolithiasis Treatments
- Renal cell carcinoma treatment
- Nuclear Receptors and Signaling
- Cancer, Lipids, and Metabolism
- Cancer-related molecular mechanisms research
Third Xiangya Hospital
2022-2024
Central South University
2012-2023
Xiangya Hospital Central South University
2012
Anacardic acid (AA) is a mixture of 2-hydroxy-6-alkylbenzoic homologs. It widely regarded as non-specific histone acetyltransferase inhibitor p300. The effects and the mechanisms AA in LNCaP cells (prostate cancer cells) remain unknown. To investigate effect on cells, we had carried out several experiments found that inhibits cell proliferation, induces G1/S cycle arrest apoptosis cell. via which acts may be due to following aspects. First, can regulate p300 transcription protein level...
Anacardic acid (AA) is a mixture of 2-hydroxy-6-alkylbenzoic homologs. It widely regarded as non-specific histone acetyltransferase inhibitor p300. The effects and the mechanisms AA in LNCaP cells (prostate cancer cells) remain unknown. To investigate effect on cells, we had carried out several experiments found that inhibits cell proliferation, induces G1/S cycle arrest apoptosis cell. via which acts may be due to following aspects. First, can regulate p300 transcription protein level...
Severe hydronephrosis increases the risk of urinary tract infection and irretrievable renal fibrosis. While TGFβ1-mediated fibrotic changes in proximal tubular epithelial cells fatty acid oxidation (FAO) deregulation contribute to fibrosis hydronephrosis. Firstly, a few elements were analyzed this paper, including differentially-expressed long non-coding RNAs (lncRNAs), miRNAs correlated CPT1A, RXRA, NCOA1. This paper investigated TGFβ1 effects on lncRNA FABP5P3, NCOA1 expression HK-2...