Mengyue Gao

ORCID: 0009-0007-6045-7490
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About
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Research Areas
  • Nanoplatforms for cancer theranostics
  • Luminescence and Fluorescent Materials
  • Electrocatalysts for Energy Conversion
  • Advanced battery technologies research
  • Aerogels and thermal insulation
  • Advanced Nanomaterials in Catalysis
  • S100 Proteins and Annexins
  • Organic Light-Emitting Diodes Research
  • Analytical Chemistry and Sensors
  • Surface Modification and Superhydrophobicity
  • Advancements in Transdermal Drug Delivery
  • Advanced biosensing and bioanalysis techniques
  • Advanced Materials and Mechanics
  • Solar Thermal and Photovoltaic Systems
  • Advanced Drug Delivery Systems
  • Photodynamic Therapy Research Studies
  • Supercapacitor Materials and Fabrication
  • Viral gastroenteritis research and epidemiology
  • Metal complexes synthesis and properties
  • Solar-Powered Water Purification Methods
  • Polydiacetylene-based materials and applications
  • Advanced Photocatalysis Techniques
  • Concrete and Cement Materials Research
  • Cell death mechanisms and regulation
  • Mine drainage and remediation techniques

Nanjing University
2018-2025

Biotechnology Research Institute
2025

Nanjing Drum Tower Hospital
2025

Donghua University
2021-2024

Wuhan Academy of Agricultural Sciences
2023-2024

University of Hong Kong
2024

State Key Laboratory of Synthetic Chemistry
2024

Ningxia University
2023

East China University of Science and Technology
2023

Nantong University
2023

Abstract The hierarchical combination of mineral and biopolymer building blocks is advantageous for the notable properties structural materials. Integrating silane cellulose nanofibers into high‐performance hybrid aerogels promising yet remains challenging due to unsatisfied interface connections. Here, an interfacial engineering strategy introduced via freeze–drying‐induced wetting mineralization reinforce porous network, resulting in mineral‐coated nanocellulose a simple consecutive...

10.1002/adfm.202009349 article EN Advanced Functional Materials 2021-01-29

Abstract Solar-driven interfacial evaporation is an emerging technology for water desalination. Generally, double-layered structure with separate surface wettability properties usually employed evaporator construction. However, creating materials tunable a great challenge because the of existing monotonous. Herein, we report vinyltrimethoxysilane as single molecular unit to hybrid bacterial cellulose (BC) fibrous network, which can be built into robust aerogel entirely distinct through...

10.1007/s40820-023-01034-4 article EN cc-by Nano-Micro Letters 2023-03-10

Abstract Thermal protection under extreme conditions requires materials with excellent thermal insulation properties and exceptional mechanical to withstand a variety of complex external stresses. Mesoporous silica aerogels are the most widely used due their ultralow conductivity. However, they still suffer from fragility structural instability in practical applications. Herein, nacre‐mimetic nanocomposite aerogel, synthesized via situ growth inorganic minerals lamellar cellulose nanofibrous...

10.1002/adma.202300813 article EN Advanced Materials 2023-04-21

Rapid and sensitive detection of foodborne bacteria is great significance in guaranteeing food safety preventing diseases. A bifunctional Au@Pt core–shell nanozyme with excellent catalytic properties high surface-enhanced Raman scattering (SERS) activity was developed for the highly Salmonella typhimurium based on a label-free SERS strategy. The ultrathin Pt shell (about 1 nm) can catalyze Raman-inactive molecules into Raman-active reporters, greatly amplifying amount signal molecules....

10.1021/acs.analchem.3c00251 article EN Analytical Chemistry 2023-04-09

Near-infrared (NIR) light-triggered and separable segmented microneedles (MNs), consisting of lauric acid polycaprolactone (LA/PCL) arrowheads poly(vinyl alcohol) (PVA/PVP) supporting bases, have been fabricated. A hypoglycemic drug (metformin) photothermal conversion factor (Cu7S4 nanoparticles) are encapsulated into LA/PCL arrowheads. Due to the dissolution soluble bases after absorption tissue fluid, MNs can be embedded skin insertion. Under NIR-light irradiation, exhibit an excellent...

10.1021/acsbiomaterials.8b00642 article EN ACS Biomaterials Science & Engineering 2018-06-20

Herein, an NIR-responsive polymeric microneedle (MN) system incorporated with metformin-loaded and polydopamine/lauric-acid-coated (PDA/LA-coated) hollow mesoporous SiO2 has been developed for transdermal delivery of antidiabetic drug (metformin). First, was loaded within nanoparticles (HMSNs) by a diffusion method. Then, PDA as photothermal conversion agent lauric acid (LA) phase change material (PCM) were coated onto the HMSN to form nanocarriers. Finally, these PDA/LA-coated HMSNs...

10.1021/acsabm.8b00470 article EN ACS Applied Bio Materials 2018-11-23

Abstract Despite the impressive progress of stimuli‐responsive fluorescent materials, little is known about influence confinement created by crystalline polymer over fluorescence properties molecules. The effects on an aggregation‐induced emission luminogen (AIEgen) are investigated using computational simulations, which reveal that confined space induces AIEgens to take a more planar conformation, resulting in red‐shifted spectrum. With this property, study extended explore generated...

10.1002/agt2.338 article EN cc-by Aggregate 2023-03-24

The separable microneedles (MNs), consisted of upper metformin-loaded PCL arrowheads and lower PVA/PCL supporting array, have been fabricated by separately molding method. thermal ablation MNs were capped on dissolving solid array. as-fabricated exhibited an excellent change due to the low melting point PCL. After insertion into skin, could be embedded skin. When exposed stimulus, causing melt enabling release encapsulated metformin thermally modulated.

10.1080/00914037.2018.1517347 article EN International Journal of Polymeric Materials 2018-11-08

Abstract Fluorescent proteins (FPs) are an indispensable part of modern biology. Numerous studies utilize FPs for protein labeling and cell tracking purposes. They commonly fused with to aid in their visualization. It is generally assumed that these FP tags have minimal impact on the properties fusion proteins. Do types affect function characteristics target earth? So far, there no definite answer. annexin A5 (AnxA5) has been extensively employed as apoptosis probes. However, except...

10.1002/pro.70086 article EN Protein Science 2025-03-18

Elastin-like polypeptide covalently was linked with IR820 in an aqueous environment, followed by self-assembly into nanoparticles after adding to zinc ions solution. ELP-IR820 significantly accumulated at the tumor site.

10.1039/c8bm00399h article EN Biomaterials Science 2018-01-01

Abstract Inflammatory bowel disease (IBD) is a chronic and relapsing disorder for many people associated with poor health. Although there are some clinical drugs IBD treatment, the development of effective therapeutics on patients has always been necessary. Here, we show that externalized phosphatidylserine (PS) observed surface colonic capillaries. Annexin A5 (ANXA5) high affinity PS good targeting to colon effectively alleviates experimental colitis. In contrast, ANXA5 mutant (A5m) lacking...

10.1038/s41392-021-00626-z article EN cc-by Signal Transduction and Targeted Therapy 2021-06-16

Tin (Sn) as a co-catalyst exerts substantial influence on multiple electrocatalytic reactions. Delving into Sn's role in electrocatalysts and pioneering novel strategies have an immense impact for green synthesis energy production.

10.1039/d3qi02010j article EN Inorganic Chemistry Frontiers 2023-12-15

Abstract Facile non‐radiative decay of low‐lying metal‐centered (MC) dd excited states has been well documented to pose a significant obstacle the development phosphorescent Ni II complexes due substantial structural distortions between state and ground state. Herein, we prepared series dinuclear 2 II,II by using strong σ‐donating carbene‐phenyl‐carbene (C NHC C phenyl ) pincer ligands, their Pt Pd analogues. Dinuclear bridged formamidinate/α‐carbolinato ligand exhibit short Ni−Ni distances...

10.1002/anie.202414411 article EN cc-by Angewandte Chemie International Edition 2024-09-25

The development of optical humidity detection has been considerable interest in highly integrated wearable electronics and packaged equipment. However, improving their capacities for color recognition at ultralow response–recovery rate remains a significant challenge. Herein, we propose type hybrid water-harvesting channel to construct brand-new passive fluorescence sensors (PFHSs). Specifically, the channels involve porous metal–organic frameworks hydrophilic poly(acrylic acid) network that...

10.1021/acsami.4c05437 article EN ACS Applied Materials & Interfaces 2024-05-15

Abstract Amyloid‐β 1‐42 (Aβ ) is strongly associated with Alzheimer's disease (AD). The aim of this study to elucidate whether and how miR‐6076 participates in the modulation amyloid‐β (Aβ)‐induced neuronal damage. To construct damage model, SH‐SY5Y cells were treated Aβ . By qRT‐PCR, we found that significantly upregulated ‐treated cells. After inhibition, p‐Tau apoptosis levels downregulated, cell viability was increased. Through online bioinformatics analysis, B‐cell lymphoma 6 (BCL6) a...

10.1111/jcmm.17999 article EN cc-by Journal of Cellular and Molecular Medicine 2023-10-17
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