Zhijin Chen

ORCID: 0009-0007-6084-9080
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About
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Research Areas
  • Pancreatic and Hepatic Oncology Research
  • Facility Location and Emergency Management
  • Glioma Diagnosis and Treatment
  • Spine and Intervertebral Disc Pathology
  • Antimicrobial Resistance in Staphylococcus
  • Bacteriophages and microbial interactions
  • Radiation Therapy and Dosimetry
  • Spinal Fractures and Fixation Techniques
  • Vascular Malformations and Hemangiomas
  • Bone and Joint Diseases
  • Fungal Infections and Studies
  • Surgical site infection prevention
  • Inorganic and Organometallic Chemistry
  • Adrenal and Paraganglionic Tumors
  • Influenza Virus Research Studies
  • Advanced Radiotherapy Techniques
  • Cancer Research and Treatment
  • Management of metastatic bone disease
  • Optimization and Mathematical Programming
  • Bacterial biofilms and quorum sensing
  • Reconstructive Surgery and Microvascular Techniques
  • SARS-CoV-2 and COVID-19 Research
  • Healthcare Operations and Scheduling Optimization
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Streptococcal Infections and Treatments

University of Science and Technology Beijing
2023-2024

Ruijin Hospital
2015-2024

Shanghai Jiao Tong University
2015-2024

Henan Polytechnic University
2023

Dongguan People’s Hospital
2017

Shanghai Public Health Clinical Center
2015

Army Medical University
2011-2014

Chinese PLA General Hospital
2005

Nanjing Institute of Technology
1992

ABSTRACT The emergence of Panton-Valentine leukocidin (PVL)-positive methicillin-resistant Staphylococcus aureus (MRSA) is a public health concern worldwide. PVL associated with community-associated MRSA and linked to skin soft tissue infections (SSTIs). However, genes have also been detected in care-associated (HA) isolates. diseases PVL-positive HA-MRSA isolates the distributions PVL-encoding bacteriophages not determined. In this study, total 259 strains isolated between 2009 2012 China...

10.1128/jcm.01722-14 article EN Journal of Clinical Microbiology 2014-10-23

ObjectivesMethicillin-resistant Staphylococcus aureus (MRSA) infection is increasing and causing global concern. The mechanism of MRSA resistance to amikacin poorly understood. We report on the first matched-pair study reveal that phenotypic cell wall thickening associated with adaptive amikacin.

10.1093/jac/dks522 article EN Journal of Antimicrobial Chemotherapy 2013-01-15

The aim of the current study was to investigate synergistic efficacy Robo1 bichimeric antigen receptor-natural killer cell (BiCAR-NK) immunotherapy and 125I seed brachytherapy in an orthotopic pancreatic cancer mouse model.The tumor model established with human BxPC-3 cells expressing red fluorescent protein. mice were treated implantation alone or combination seeds Robo1-specific CAR-NK cells. To assess inhibition, vivo fluorescence imaging conducted. 7 Tesla magnetic resonance (7T-MR)...

10.21873/anticanres.13796 article EN Anticancer Research 2019-11-01

Objectives To compare the biological effects of 125I seeds continuous low-dose-rate (CLDR) radiation and 60Co γ-ray high-dose-rate (HDR) on non-small cell lung cancer (NSCLC) cells. Materials Methods A549, H1299 BEAS-2B cells were exposed to CLDR or HDR radiation. The survival fraction was determined using a colony-forming assay. cycle progression apoptosis detected by flow cytometry (FCM). expression apoptosis-related proteins caspase-3, cleaved-caspase-3, PARP, cleaved-PARP, BAX Bcl-2...

10.1371/journal.pone.0133728 article EN cc-by PLoS ONE 2015-08-12

To evaluate a 3D-printed coplanar template for iodine-125 seed implantation therapy in patients with pancreatic cancer.A retrospective analysis of our database was performed, and total 25 cancer who underwent between January 2014 November 2017 were analyzed. Of these, 12 implantations assisted by (group A), 13 performed freehand selected as control group B). A 3D designed printed according to preoperative CT scan treatment planning system. The seeds then implanted using the guide. Dosimetric...

10.3748/wjg.v24.i46.5280 article EN cc-by-nc World Journal of Gastroenterology 2018-12-13

The objective of this study is to investigate the safety and efficacy 125I seed interstitial implantation brachytherapy for metastatic epidural spinal cord compression (MESCC) as well life quality patients.From April 2009 May 2015, 28 patients who met eligibility criteria were retrospectively reviewed. number implanted seeds ranged from 7 62, with appropriate activity 0.5-0.8 mCi. postplan showed that matched peripheral dose (MPD) tumors was 80-140 Gy. duration follow-up 1 32 months a median...

10.4103/jcrt.jcrt_938_17 article EN Journal of Cancer Research and Therapeutics 2018-01-01

Before the occurrence of disasters, medical supplies should have been prepared at warehouses to support infected cases. As possible mismatch between initial supply preparedness and actual disaster situation, it would trigger off serious social outcomes. Thus, taking adjustment operations among is an imperative task ensure sustainable development society. However, a single-period logistics action with fully uncertain information usually leads sub-optimal schemes. In this sense, multi-period...

10.1109/access.2023.3307396 article EN cc-by-nc-nd IEEE Access 2023-01-01

The incidence of pancreatic cancer is increasing worldwide. Approximately, 60% patients with have distant metastases at the time diagnosis, which only 10% can be removed using standard resection. Further, derive limited benefits from chemotherapy or radiotherapy. As such, alternative methods to achieve local control emerged, including permanent iodine-125 seed interstitial brachytherapy. In 2023, Chinese College Interventionalists, affiliated Medical Doctor Association, organized a group...

10.4103/jcrt.jcrt_2368_23 article EN Journal of Cancer Research and Therapeutics 2024-08-01

Abstract Polymeric substrates containing salicylidenimine ligands as discrete units can be obtained by reacting chloromethylated divinylbenzene styrene copolymer with amines, followed condensation salicylaldehyde. Polymer‐supported Schiff base iron (III) complexes have been prepared and their IR spectra Mössbauer measured. Catalytic activity of supported tested using decomposition hydrogen peroxide a model reaction.

10.1002/app.1992.070450607 article EN Journal of Applied Polymer Science 1992-06-25

Objective To investigate the clinical value of coplanar template-assisted CT guided radioactive seeds implantation in treatment pancreatic carcinoma. Methods A total 22 advanced carcinoma patients underwent were retrospectively analyzed. Ten treated with an average age (65±10) years (48 to 77 years). Tweleve without template assist (68±13) (47 84 The preoperative planning designs and postoperative dosimetry verifications performed for all patients. dose related parameters including...

10.3760/cma.j.issn.1005-1201.2017.12.015 article EN Zhonghua fangshexian yixue zazhi 2017-12-10

To assess percutaneous vesselplasty's safety and efficacy in treating pathological vertebral compression fractures (VCFs).This retrospective review covered nine patients with an equal number of symptomatic VCFs treated vesselplasty. The study assessed the patients' pain scores, subjective conditions, imaging guidance, incidence procedure-related complications.The were at T4 L5 spine regions. procedure success rate was 100%. In 88.89% (8/9) examined cases, there a posterior body or pedicle...

10.4103/jcrt.jcrt_1349_21 article EN Journal of Cancer Research and Therapeutics 2021-01-01

Objective To investigate strain distribution and antifungal susceptibility of fungus isolates from acquired immune deficiency syndrome (AIDS) patients Shanghai public health clinic center. Methods The funus clinical specimens in-hospital AIDS in our hospital between January 2010 December 2014 were retrospectively analyzed. Results Of the 3 155 hospitalized with human immunodeficiency virus (HIV)/AIDS, a total 11 291 culture collected, which 1 786 (15.82%) positive. Nine hundred...

10.3760/cma.j.issn.1000-6680.2015.09.006 article EN Zhonghua chuanranbing zazhi 2015-09-15

Large-scale epidemics impose significant burdens globally and cause an imbalance of medical supplies among different regions owing to the dissimilarly unevenly distributed prevalence infection. Along with rebalancing limited meet demand supply requirements, ensuring that are allocated support affected is also important. Hence, this study focuses on collaborative allocating process balance supply. The law diminishing marginal utility incorporated in quantify principle fairness supplies....

10.1051/ro/2023089 article EN cc-by RAIRO - Operations Research 2023-06-12

The ongoing impact of the novel coronavirus disease 2019 (COVID-19) on work and daily life persists as we transition from emergency to normal circumstances. continuous mutation viral strains has resulted in a shift single strain multiple cross-strains, contributing spread epidemic. Variations infection rates same occur because implementation diverse preventive measures at different times. This study investigated dynamics pandemic presence concurrent strains. Building classical Susceptible,...

10.1016/j.jnlssr.2023.07.002 article EN cc-by-nc-nd Journal of Safety Science and Resilience 2023-08-06

Objective To analyze the related risk factors of orthopedic surgical site infection and investigate application Wechat follow-up so as to provide reference for reducing after surgery. Method A total 1 453 patients with surgery from Jan. 2016 Dec. were selected retrospectively analyzed at time hospitalization post-discharge. Results Among surgery, there 26 cases infection, accounting 1.79%; occurred in 8 427 discharge, 0.56%. Age, basic disease, operation, implant situation,...

10.3760/cma.j.issn.1007-1245.2017.14.009 article EN 国际医药卫生导报 2017-07-15
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