A5107495926- Breast Cancer Treatment Studies
- HER2/EGFR in Cancer Research
- Cancer Treatment and Pharmacology
- Advanced Breast Cancer Therapies
- Reconstructive Surgery and Microvascular Techniques
- Anatomy and Medical Technology
- Breast Lesions and Carcinomas
- Breast Implant and Reconstruction
P.A. Hertzen Moscow Oncology Research Institute
2024-2025
Ministry of Health of the Russian Federation
2024-2025
Medical Radiological Research Center
2025
The aim of the study was to search for data on effectiveness neoadjuvant therapy hormone-positive HER2-negative breast cancer. Material and methods. literature conducted in PubMed RISC databases. Publications from 2012 2024 were found. keywords used were: “breast cancer”, “bneoadjuvant chemotherapy”, “bsurgery”, “bluminal tumors”, “bhormone-dependent “bbreast-conserving surgery”. Results. indications chemotherapy patients with cancer are discussed, considering possibility achieving clinical...
Aim. To study the role of progesterone receptor expression, tumor grade and Ki-67 level as possible predictors pathological complete response (pCR) to neoadjuvant chemotherapy in patients with stage IIA–IIB (cT1–2N1, cT2–3N0M0) breast cancer hormone-positive HER2-negative subtype. Materials methods . We retrospectively analysed efficacy (4AC+12P/4T) 100 stages subtype treated at P.A. Hertsen Moscow Oncology Research Institute from 2013 2022. The depending on tumour (G) proliferation index...
Background. Breast reconstruction with allo- and/or autologous materials is becoming the most popular surgical treatment option for breast cancer patients. The aim of study. To evaluate efficacy reconstructions in patients depending on technique reintervention. Materials and methods. object study was a group 70 female who underwent repeat using endoprosthesis, flap autografting, and/o r combination these methods, between 2016 2023. age ranged from 25 to 68 years. mean 46.8 ± 8.6 Body mass...
Objective. To evaluate clinical and pathological responses to neoadjuvant polychemotherapy (NACT) in patients with stage IIA-IIB breast cancer of hormone-positive HER2-negative subtype depending on the level tumor cell proliferation index (Ki-67), analyze volume surgical intervention. Material methods. We analyzed results treatment 100 who received NACT according 4AC+12P/4T regimen at first complex followed by Department Oncology Reconstructive Plastic Surgery Breast Skin P.A. Herzen Moscow...
Objective. To evaluate the effectiveness of repeated breast reconstruction in cancer patients depending on complications after primary reconstruction. Material and methods. There were 117 who underwent one-stage with endoprosthesis, autograft and/or their combination. Results. A retrospective analysis included complex treatment 2017—2021. Surgical (subcutaneous/skin-sparing mastectomy reconstruction) was realized at department oncology reconstructive surgery skin. Analysis silicone...