A5101900390- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Cancer Studies
- Alzheimer's disease research and treatments
- Ultrasound and Hyperthermia Applications
- Nutritional Studies and Diet
- Molecular Biology Techniques and Applications
- Folate and B Vitamins Research
- Lung Cancer Research Studies
- Molecular Sensors and Ion Detection
- Cancer Immunotherapy and Biomarkers
- Cancer Cells and Metastasis
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Liver Disease Diagnosis and Treatment
- Protease and Inhibitor Mechanisms
- Pancreatic and Hepatic Oncology Research
- Neuroblastoma Research and Treatments
- Diet, Metabolism, and Disease
- Dental Radiography and Imaging
- Neuroscience and Neuropharmacology Research
- Endoplasmic Reticulum Stress and Disease
- Gastric Cancer Management and Outcomes
- Immune cells in cancer
- Reproductive System and Pregnancy
Hong Kong Baptist University
2024-2025
First Affiliated Hospital of GuangXi Medical University
2024-2025
Guangxi Medical University
2024-2025
Sun Yat-sen University
2014-2024
Chongqing Medical University
2023-2024
Children's Hospital of Chongqing Medical University
2023-2024
Sun Yat-sen University Cancer Center
2023
Xiamen University
2023
Southern Medical University
2014-2020
Foshan Maternity and Child Health Care Hospital
2019
Abstract Objectives This study was designed to explore and validate the value of different machine learning models based on ultrasound image-omics features in preoperative diagnosis lymph node metastasis pancreatic cancer (PC). Methods research involved 189 individuals diagnosed with PC confirmed by surgical pathology (training cohort: n = 151; test 38), including 50 cases metastasis. Image-omics were extracted from images. After dimensionality reduction screening, eight algorithms, logistic...
Background: There is limited information about gene-environment interaction on the occurrence and progression of Alzheimer’s disease. Objective: To explore effect environmental low-dose cadmium (Cd) exposure progress disease underlining mechanism. Methods: We administered 1 mg/L, 10 mg/L chloride (treated groups), water (control group) to C57BL/6J APP/PS1 mice through drinking water, from one week before mating, until offspring were sacrificed at 6 months age. The behaviors, Cd level,...
Abstract Introduction:Inflammation has a significant impact on the tumor microenvironment (TME) of osteosarcoma (OS). Nevertheless, due to high heterogenecity and variable inflammatory characteristics among OS patients, it is still unclear which factors or immune/stroma cell types are crucially associated with prognosis. Therefore, essential explore immune infiltration pattern related core genes in OS. Method:We combined bulk RNA-seq data 88 (OS) patients from TARGET database single...
The mechanofluorochromic properties of three C6-unsubstituted tetrahydropyrimidines (THPs), namely, diethyl 1,2,3-triphenyl-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylate (1), dimethyl 1,2,3-tri(4-trifluoromethylphenyl)-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylate (2), and 1,2,3-tri(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylate (3), with aggregation-induced emission (AIE) characteristics were investigated. blue-green/cyan emissions the THPs can be switched...
<h3>Background</h3> Claudin 18.2 (CLDN18.2), a tetraspanin family member essential for the formation of tight junctions,<sup>1</sup> is highly expressed in gastric, pancreatic and esophageal adenocarcinomas, with physiological expression restricted to gastric mucosal epithelial cells.<sup>2</sup> CLDN18.2 validated therapeutic target; zolbetuximab, CLDN18.2-directed monoclonal antibody, demonstrated clinical benefit combination chemotherapy CLDN18.2-high cancer.<sup>3 4</sup> Similarly,...
<title>Abstract</title> To investigate the time course changes of key pathological features Alzheimer’s disease (AD) and relationship between vascular damage, neuro-inflammation Aβ in AD model. VEGFR2 expression, number levels cortex cerebrospinal fluid, cortical serum inflammatory factor levels, autonomic activity/memory were analyzed APP/PS1 mice from 1 to 12-month-old. Transcriptomic analysis capillaries one-month-old pathway performed. Validation transcriptome data patients GEO database....
Oral cancer, which is also called mouth cancer of the lining mouth, lips, or upper throat that has appeared in more than 355,000 people worldwide and caused 177,000 deaths, so it essential to diagnose as early possible. Computed tomography (CT) scan conducive oral diagnosis, but classifying CT images cyst manually difficult time-consuming. A novel intelligent model based on improved Inception-v3 for automatically proposed this paper. We replace conventional convolution block with Inverted...
Abstract Aims To explore the relationship between serum folic acid (FA) or Vitamin B12 (VB12) and elevated BP in children adolescents. Methods A nested case-control study was conducted to select 326 subjects (116:210) from an established cohort. And a cohort also conducted, which included 270 participants without hypertension at baseline followed 2019. Questionnaires, physical examinations, blood biochemical tests were performed follow-up. The relationships FA, VB12, pressure (BP) levels...