- Lymphoma Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatitis Pathology and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastrointestinal disorders and treatments
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal Tumor Research and Treatment
- Lung Cancer Treatments and Mutations
- Blood Pressure and Hypertension Studies
- Retinal Imaging and Analysis
- Viral-associated cancers and disorders
- Glaucoma and retinal disorders
- Histiocytic Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Monoclonal and Polyclonal Antibodies Research
- Multiple Myeloma Research and Treatments
- HER2/EGFR in Cancer Research
- Pituitary Gland Disorders and Treatments
- Acute Myeloid Leukemia Research
- Autoimmune and Inflammatory Disorders
- Lung Cancer Research Studies
- Cardiovascular Health and Disease Prevention
- Sarcoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
Guangxi Medical University
2022-2025
First Affiliated Hospital of GuangXi Medical University
2022-2025
Wuhan Puai Hospital
2025
Eye & ENT Hospital of Fudan University
2024
First Affiliated Hospital Zhejiang University
2024
Union Hospital
2024
Huazhong University of Science and Technology
2024
Tianjin Medical University Cancer Institute and Hospital
2015-2023
Tianjin Medical University
2011-2023
Chongqing Medical University
2023
Carotid intima-media thickness (IMT) and diameter, stiffness, wave reflections, are independent important clinical biomarkers risk predictors for cardiovascular diseases. The purpose of the present study was to establish nationwide reference values carotid properties healthy Chinese adults explore potential determinants.
Tropical Candida spondylitis is an uncommon cause of lower back pain in patients, especially non-tropical areas or patients not at risk immunocompromise. A 65-year-old woman presented with a six-month history poorly managed low pain, now accompanied by numbness and both extremities. Her medical was significant for tertiary hypertension. Inflammatory markers were mildly elevated. MRI fluid sequences revealed lamellar enhancement the L4-5 vertebral bodies, narrowing intervertebral space,...
Background Clinically effective markers for the diagnosis of major depressive disorder (MDD) are lacking. Alterations in retinal features closely related to pathophysiological progression MDD. However, reliable retina-related diagnostic model MDD remains be developed. Thus, our study aimed quantitatively evaluate vascular and structural changes patients develop a based on parameters. Methods Seventy-eight with 47 healthy controls (HCs) underwent vessel density structure examination using...
The present study aimed to evaluate the influence of biological characteristics hepatocellular carcinoma (HCC) on Liver Imaging Reporting and Data System (LI-RADS) v2017 category contrast-enhanced ultrasound (CEUS) in patients with high risk compare outcomes among different categories after radical resection.Between June 2017 December 2020, standardized CEUS data liver nodules were prospectively collected from multiple centers across China. We conducted a retrospective analysis HCCs...
To establish a diagnostic model by combining imaging features with enhanced CT texture analysis to differentiate pancreatic serous cystadenomas (SCNs) from mucinous (MCNs).Fifty-seven and 43 patients pathology-confirmed SCNs MCNs, respectively, one center were analyzed divided into training cohort (n = 72) an internal validation 28). An external 28) another was allocated. Demographic radiological information collected. The least absolute shrinkage selection operator (LASSO) recursive feature...
Pancreatic cancer (PAAD) is one of the most malignant tumors with worst prognosis. The abnormalities in mitochondrial energy metabolism pathway are intimately correlated occurrence and progression cancer. For diagnosis treatment pancreatic cancer, abnormal genes system may offer new targets biomarkers. In this study, we compared dysregulated metabolism-associated pathways PAAD based on samples Cancer Genome Atlas (TCGA) database normal pancreas from Genotype Tissue Expression project (GTEx)...
Rationale: Brucellosis is a multisystem infection found worldwide that has broad range of characteristics, which from acute fever and hepatomegaly to chronic infections most commonly affect the central nervous system, cardiovascular or skeletal system. Gastrointestinal splanchnic artery involvements in brucellosis are relatively uncommon. Patient concerns: We report case an adolescent presenting as intermittent abdominal pain, diarrhea, fever, with intestinal tract involvement. And stenosis...
The prognostic significance of serum lactate dehydrogenase (LDH) level in thymic carcinoma (TC) remains unclear. Therefore, we evaluated the role pretreatment LDH prognosis for TC this study.Sixty consecutive surgical patients were analyzed study with pathologic confirmed Sun Yat-sen University Cancer Center from June 1996 to 2014.The cut-off value was 210.50 IU/L. In both univariate analysis and multivariable analysis, only (P=0.027) pathological Masaoka stage (P=0.041) associated overall...
Purpose:The aim of the present study was to investigate effect trastuzumab on pathological complete response (pCR) rate and event-free survival (EFS) in neoadjuvant-treated HER2-positive breast cancer with a low infiltrating level tumor-infiltrating lymphocytes (TILs).Patients Methods: The TILs evaluated hematoxylin eosin-stained slides from diagnostic needle biopsies, defined as < 10%.Data 179 patients were retrospectively reviewed compared according whether administered or not.The...
This study was aimed to investigate the expression levels of CXCR4 and VEGF in serum patients with DLBCL their clinical significances. The peripheral blood 44 newly diagnosed 20 healthy adults as a control group were chosen for study. And detected by ELISA. results showed that expressions higher than those (P < 0.05). positively correlated patients, correlation coefficient 0.743 LDH, immunotyping, number extranodal involvements, Ann Arbor staging ECOG performance score; while involvements...
Lymphoblastic lymphoma (LBL) comprises 2% to 4% of non-Hodgkin lymphomas cases in adults, which 85% 90% LBL adults is T-cell phenotype. This study was aimed evaluate the clinical characteristics and prognostic factors patients with mediastinal T-LBL. Based on retrospective analysis data 35 T-LBL during period from January 1998 2011, were summarized. The results showed that total identified (male 24 female 11), a median age 19 (5 - 52) years. majority stage III/IV, 16 (45.7%) presented bulky...
Thermal ablation combined with systemic therapy is an accepted treatment of colorectal liver oligometastases (CLOM). Consensus lacking regarding the optimal timing thermal relative to therapy.
Objectives The aims of this study were to establish a scoring model for the differential diagnosis pancreatic cancer (PC) and chronic pancreatitis (CP) evaluate its diagnostic efficacy. Methods data 502 patients with PC 210 CP at Peking Union Medical College Hospital from January 1999 December 2013 retrospectively analyzed. Binary logistic regression was applied prediction diagnosis. verified using method leave-one-out cross-validation. Results system established 5 variables including age,...
Objective To investigate the application of Acute Gastrointestinal Injury(AGI) grading in evaluating gastrointestinal failure patients with acute pancreatitis(AP). Methods In this retrospective observational study,patients presented moderate severe AP and our hospital from October 2013 to 2016 were consecutively enrolled.Logistic regression analysis receiver operating characteristic curve used explore evaluate potential predictors failure. Results A total 202 included study,with 90...
Background: The arterial stiffening is attributed to the intrinsic structural and/or load-dependent by increased blood pressure (BP). respective lifetime alterations and major determinants of two components with normal aging are not clear. Methods: A total 3053 healthy adults (1922 women) aged 18–79 years were enrolled. carotid intima–media thickness, diameter, local BPs automatically determined radio frequency ultrasound system. Peterson Young elastic moduli then calculated represent...