A5101856490- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Heavy metals in environment
- Metal-Organic Frameworks: Synthesis and Applications
- Molecular Sensors and Ion Detection
- Nanoparticle-Based Drug Delivery
- Drug Solubulity and Delivery Systems
- Geochemistry and Geologic Mapping
- Computational Drug Discovery Methods
- Thermal properties of materials
- Radioactivity and Radon Measurements
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Mechanical Failure Analysis and Simulation
- Ionic liquids properties and applications
- Analytical Chemistry and Sensors
- Dendrimers and Hyperbranched Polymers
- Synthetic Organic Chemistry Methods
- Soil Geostatistics and Mapping
- Cancer therapeutics and mechanisms
- Organometallic Complex Synthesis and Catalysis
- Process Optimization and Integration
- Biosensors and Analytical Detection
- Heavy Metal Exposure and Toxicity
- Neurogenetic and Muscular Disorders Research
Zhoukou Normal University
2025
Shandong Academy of Sciences
2023-2024
Qilu University of Technology
2023-2024
Southern University of Science and Technology
2020-2024
Ministry of Agriculture and Rural Affairs
2024
Puer University
2024
CRRC (China)
2023-2024
Chongqing Academy of Agricultural Sciences
2022-2024
Beijing University of Chinese Medicine
2022-2023
Xiamen University
2023
Hypoxia not only promotes tumor metastasis but also strengthens resistance to therapies that demand the involvement of oxygen, such as radiation therapy and photodynamic (PDT). Herein, taking advantage high reactivity manganese dioxide (MnO 2 ) nanoparticles toward endogenous hydrogen peroxide (H O within microenvironment generate , multifunctional chlorine e6 (Ce6) loaded MnO with surface polyethylene glycol (PEG) modification (Ce6@MnO ‐PEG) are formulated achieve enhanced tumor‐specific...
Extensive efforts have been directed at the discovery, investigation and clinical monitoring of targeted therapeutics. These may be facilitated by convenient access genetic, proteomic, interactive other aspects therapeutic targets. Here, we describe an update Therapeutic target database (TTD) previously featured in NAR. This includes: (i) 2000 drug resistance mutations 83 targets 104 target/drug regulatory genes, which are resistant to 228 drugs targeting 63 diseases (49 61 with patient...
Nanoscale metal–organic particles (NMOPs) are constructed from metal ions and organic bridging ligands via the self-assembly process. Herein, we fabricate NMOPs composed of Mn2+ a near-infrared (NIR) dye, IR825, obtaining Mn-IR825 NMOPs, which then coated with shell polydopamine (PDA) further functionalized polyethylene glycol (PEG). While in such Mn-IR825@PDA–PEG offers strong contrast T1-weighted magnetic resonance (MR) imaging, IR825 NIR optical absorbance shows efficient photothermal...
Cancer combination therapy to treat tumors with different therapeutic approaches can efficiently improve treatment efficacy and reduce side effects.Herein, we develop a theranostic nano-platform based on polydopamine (PDA) nanoparticles, which then are exploited as versatile carrier allow simultaneous loading of indocyanine green (ICG), doxorubicin (DOX) manganese ions (PDA-ICG-PEG/DOX(Mn)), enable imaging-guided chemo & photothermal cancer therapy.In this system, ICG acts agent, shows...
Soil salinization is a global issue resulting in soil degradation, arable land loss and ecological environmental deterioration. Over the decades, multispectral hyperspectral remote sensing have enabled efficient cost-effective monitoring of salt-affected soils. However, potential sensors installed on an unmanned aerial vehicle (UAV) to estimate map salinity has not been thoroughly explored. This study quantitatively characterized estimated field-scale using electromagnetic induction (EMI)...
The introduction of different pore diameters in metal organic frameworks (MOFs) could adjust their drug delivery performance. MOFs with customized structures have potential application value targeted delivery. However, no research on this topic has been found so far. In report, isoreticular (IRMOFs) taken as a typical case tailor-made MOFs, the size which is enlarged (average BJH sizes about 2.43, 3.06, 5.47, and 6.50 nm were determined for IRMOF-1, IRMOF-8, IRMOF-10, IRMOF-16,...
For the first time, we demonstrated that FeSe<sub>2</sub> nanoparticles may have great potential as a safe, multi-functional theranostic agent for imaging guided photothermal treatment of cancer.
Water droplet unidirectional transport on the asymmetric superhydrophobic surface has attracted much interest in theory analysis and applications, such as self-cleaning, antifogging, anti-icing, heat transfer, so on. Different from symmetrical performance uniform topographies, droplets acting exhibit an anisotropic state easily roll off along special direction. This phenomenon is indicated by natural butterfly wings. The flexible asymmetrically arranged microstep induces to release outside...
Multidrug resistance (MDR) remains a primary challenge in breast cancer treatment. In the present study, D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS)-coated docetaxel-loaded liposomes were developed as novel drug delivery system to reverse MDR and enhance therapy compared with traditional liposomes, DSPE-mPEG-coated (stealth liposomes) commercial Taxotere® .Liposomes prepared by thin - film dispersion method. Evaluations performed using human MCF-7 resistant MCF-7/ADR cells....
A specific amino-based fluorescent probe was synthesized to detect Hg 2+ in living cells and zebrafish.
To reduce the energy consumption and total annual cost (TAC) of conventional extractive distillation (CED) process, this study focuses on process intensification by combination salt-based DESs entrainers, partial heat-integrated intermediate reboilers for 2-propanol + water separation process. The vapor-liquid equilibrium experiments showed that (ChCl:U:CaCl2)1:2:0.36 is most promising among all entrainers investigated. Based thermodynamic study, conceptual design CED was created to examine...
The cationic dimethyldioctadecylammonium/trehalose 6,6,9-dibehenate (DDA/TDB) liposome is as a strong adjuvant system for vaccines, with remarkable immunostimulatory activity. mucosal administration of vaccines potential strategy inducing earlier and stronger immune responses to infectious diseases. In this study, we assessed whether the intranasal DDA/TDB liposomes combined influenza antigen A (H3N2) can be used highly efficacious vaccine induce systemic antibody responses. Confocal laser...
Nanostructured polyethylene (PE, [–CH 2 –CH –] n ) films with metal-like thermal conductivity have opened up opportunities for polymers in advanced management.
Symbiotic nitrogen fixation provides most of the required for soybean growth. Rhizobial nodulation outer proteins (Nops) have been reported to influence host specificity during symbiosis establishment. However, that interact with Nops remain unknown. In this study, we generated Sinorhizobium fredii HH103 mutants (HH103ΩNopL, HH103ΩNopT, and HH103ΩNopLΩNopT) analysed nodule number (NN) dry weight (NDW) 12 germplasms after inoculation wild-type S. or mutant strains. The analysis chromosome...
Metal–organic frameworks (MOFs) with tunable structures, high porosity, and abundant active sites are considered to be promising drug delivery systems (DDSs). In this study, novel MOFs-based nanoparticles ([email protected]) were successfully prepared using Zn-based IRMOF-16 as a carrier curcumin (CUR) the model drug. This nanocargo platform has dual capabilities, enabling simultaneous fluorescence imaging. vitro release experiments showed that released more quickly under mildly acidic...