A5073413541- Neurological disorders and treatments
- Neuroscience and Neural Engineering
- Transcranial Magnetic Stimulation Studies
- Neuroendocrine regulation and behavior
- Photoreceptor and optogenetics research
- Stress Responses and Cortisol
- Vagus Nerve Stimulation Research
- Ultrasound and Hyperthermia Applications
- Circadian rhythm and melatonin
- Obsessive-Compulsive Spectrum Disorders
- Literacy and Educational Practices
- Tryptophan and brain disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurology and Historical Studies
- S100 Proteins and Annexins
- Educational Technology in Learning
- Olfactory and Sensory Function Studies
- Nerve injury and regeneration
- Functional Brain Connectivity Studies
- Molecular Communication and Nanonetworks
- Optical Imaging and Spectroscopy Techniques
- Spanish Linguistics and Language Studies
- EEG and Brain-Computer Interfaces
- Photoacoustic and Ultrasonic Imaging
- Stress and Burnout Research
Columbia University
2019-2023
Massachusetts General Hospital
2017-2022
Harvard University
2019-2022
Iberoamerican University
2019
Marion General Hospital
2018
The neuropathological hallmarks of Alzheimer's disease include amyloid plaques and neurofibrillary tangles. Tau pathology correlates well with impaired neuronal activity dementia. Focused ultrasound coupled systemic administration microbubbles has previously been shown to open the blood-brain barrier induce an immune response, which, in AD mouse model, resulted reduction brain load. Methods: In this study, we investigated effect focused at early stages tau (pre-tangle) rTg4510 model....
Abstract Focused ultrasound-enhanced intranasal (IN + FUS) delivery is a noninvasive approach that utilizes the olfactory pathway to administer pharmacological agents directly brain, allowing for more homogenous distribution in targeted locations compared IN alone. However, whether such strategy has therapeutic values, especially neurodegenerative disorders as Parkinson’s disease (PD), remains be established. Herein, we evaluated expression of tyrosine hydroxylase (TH), rate limiting enzyme...
Rationale: Bilateral sonication with focused ultrasound (FUS) in conjunction microbubbles has been shown to separately reduce amyloid plaques and hyperphosphorylated tau protein the hippocampal formation entorhinal cortex different mouse models of Alzheimer's disease (AD) without any therapeutic agents.However, two pathologies are expressed concurrently human disease.Therefore, objective this study is investigate effects repeated bilateral sonications presence both pathologies.Methods:...
La presente investigación tuvo como objetivo optimizar los niveles de disciplina en estudiantes bachillerato, mediante la aplicación estrategias basadas prácticas restaurativas. A través una observación directa, se identificaron diversas manifestaciones indisciplina el entorno escolar, irrespeto a normas institucionales, conflictos interpersonales, desmotivación académica y desatención clase, cuales alteran negativamente clima organizacional pedagógico del aula, empleó un enfoque...
Objective. Neurostimulation technologies are important for studying neural circuits and the connections that underlie neurological psychiatric disorders. However, current methods come with limitations such as restraint on movement imposed by wires delivering stimulation. The objective of this study was to assess whether e-Particle (EP), a novel wireless neurostimulator, could sufficiently stimulate brain modify behavior without these limitations. Approach. Rats were implanted EP commercially...
Exposure to stressful or traumatic stimuli may alter hypothalamic-pituitary-adrenal (HPA) axis and sympathoadrenal-medullary (SAM) reactivity. This altered reactivity be a component cause of mental illnesses. Dissecting these mechanisms requires tools reliably probe HPA SAM function, particularly the adrenal component, with temporal precision. We previously demonstrated magnetic nanoparticle (MNP) technology remotely trigger hormone release by activating thermally sensitive ion channels....
Abstract Exposure to stress alters hypothalamic-pituitary-adrenal (HPA) axis reactivity; however, it is unclear exactly how or where within the HPA pathway these changes occur. Dissecting mechanisms requires tools reliably probe function, particularly adrenal component, with temporal precision. We previously demonstrated magnetic nanoparticle (MNP) technology remotely trigger hormone release by activating thermally sensitive ion channels. Here, we applied magnetothermal stimulation...
Este artículo se enfocó en el uso de actividades repetición que promueven desarrollo la destreza expresión oral (habla) o speaking inglés. Las repeticiones forma mecánica y significativa son tomadas para analizar relación avance del habilidades comunicación lengua extranjera. trabajo tomó origen estudios ya realizados los cuales referentes aplicación palabras frases (patrones) como fue utilizado enseñanza tradicional. Se optó por enfoque investigación tipo cuantitativo, lo respecta a...
La presente investigación tiene el objetivo de explorar las consecuencias del allanamiento morada en una población infantes y adolescentes. Se trata un estudio cualitativo cual se realizaron entrevistas a personas menores edad con dicha condición, así como profesionales psicología, fin identificar emocionales conductuales esta entre mayo setiembre año 2015. encuentran síntomas depresivos, miedo, agresividad, actitudes negativas hacia la policía autoridad, hiperactividad, ansiedad por...