A5006514720- Autoimmune Neurological Disorders and Treatments
- Peripheral Neuropathies and Disorders
- Multiple Sclerosis Research Studies
- Spinal Cord Injury Research
- Pain Mechanisms and Treatments
- Genetics and Neurodevelopmental Disorders
- Rheumatoid Arthritis Research and Therapies
- Mycobacterium research and diagnosis
- Botulinum Toxin and Related Neurological Disorders
- Myasthenia Gravis and Thymoma
- Spine and Intervertebral Disc Pathology
- Systemic Lupus Erythematosus Research
- Cytokine Signaling Pathways and Interactions
Aarhus University Hospital
2010-2025
Aalborg University Hospital
2017
Danish Pain Research Center
2010-2015
The aim of this study was to describe clinical and paraclinical characteristics all Danish patients who tested positive for anti-voltage-gated potassium channels (VGKC)-complex, anti-leucine-rich glioma-inactivated 1 (LGI1) anti-contactin-associated protein-2 antibodies in the serum/cerebrospinal fluid between 2009 2013 with follow-up interviews 2015 2016.We evaluated antibody status, symptoms leading testing, course disease, suspected diagnosis time admission as well treatment. All magnetic...
Pain is a frequent consequence of spinal cord injury (SCI) which may profoundly impair the patients' quality life. Valid experimental models and methods are therefore desirable in search for better treatments. Usually, pain assays depend on stimulus-evoked withdrawal responses; however, this spinal-mediated reflex response be particularly problematic when evaluating below-level SCI due to development hyperactive circuitries. In study, we applied compared measuring cold (acetone), static (von...
Background: In multiple sclerosis (MS), the educational gradient in diagnostic and disease-modifying treatment (DMT) delays is sparsely examined, results are mixed. Objectives: Among patients with relapsing-remitting MS (RRMS), we aimed to examine delay initiation of first DMT. Design: A nationwide cohort study. Methods: We linked Danish Multiple Sclerosis Registry other registries. Diagnostic was evaluated 4344 ⩾20 years at clinical onset from January 1, 2012, onwards, diagnosed by March...
Abstract Background Identification of mechanisms for pain/hyperalgesia following spinal cord injury requires long‐term evaluation individual subjects because the variability in effect over time humans. Methods Rats were trained on an operant escape task that determined their preference occupancy a brightly lit compartment versus dark with floor preheated to 10, 32 or 44.5 ° C . Following determination baseline preferences, animals received extradural implantation small piece polymer thoracic...
Background: Teriflunomide has been associated with an increased risk of hypertension. Real-world studies including adequate control groups are lacking. We hypothesized that patients multiple sclerosis (MS) treated teriflunomide would be at higher developing hypertension than those dimethyl fumarate. Methods: conducted a cohort study linking the Danish Multiple Sclerosis Registry national health registries during 10-year period. ( N = 2656) and fumarate 2237) exposure was defined by first...