A5089724567- Advanced Radiotherapy Techniques
- Healthcare Facilities Design and Sustainability
- COVID-19 epidemiological studies
- Graphene and Nanomaterials Applications
- Nonmelanoma Skin Cancer Studies
- Nanoplatforms for cancer theranostics
- Long-Term Effects of COVID-19
- Climate Change and Health Impacts
- Data-Driven Disease Surveillance
- COVID-19 Clinical Research Studies
- Head and Neck Cancer Studies
- Cutaneous Melanoma Detection and Management
- Zoonotic diseases and public health
- Radiation Therapy and Dosimetry
- Health disparities and outcomes
- Diverticular Disease and Complications
- Nasal Surgery and Airway Studies
- Breast Cancer Treatment Studies
- Telemedicine and Telehealth Implementation
- MXene and MAX Phase Materials
- Legionella and Acanthamoeba research
- COVID-19 and healthcare impacts
- Tuberculosis Research and Epidemiology
- Gastrointestinal disorders and treatments
- Doping in Sports
Università degli Studi eCampus
2024-2025
ASL Roma
2011-2024
Università Cattolica del Sacro Cuore
2021-2024
Agostino Gemelli University Polyclinic
2023-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2024
Azienda Sanitaria Locale Roma 3
2013-2024
University of Naples Federico II
2021
Regione Lazio
2020
The coronavirus disease (COVID-19) outbreak is rapidly progressing globally, and Italy, as one of the main pandemic hotspots, may provide some hard lessons for other countries. In this paper, we summarize current organizational capacity a pragmatic narrative account strategies activities implemented by Department Prevention (Dipartimento di Prevenzione)—the regional entity Local Health Authority Italian National Service in charge public health—since beginning outbreak. We conduct preliminary...
Globally, breast cancer is the most diagnosed invasive among women. Current therapies (e.g., chemotherapy) show numerous limitations due to lack of selectivity and involved side effects, which urgently asks for novel approaches with enhanced tumor-killing efficacy. We previously demonstrated that MXenes, new bioactive nanomaterials promising photophysical properties, are capable increase efficiency targeted photothermal therapy (PTT). In this work, we investigated effect few- multi-layer...
Between August and September 2023, three distinct autochthonous dengue virus transmission events occurred in Lazio, Italy, with the main event Rome. The involved different serotypes. No link previous imported cases was identified. Here we describe epidemiological phylogenetic analysis of first implemented control actions. multiple call for a strengthening vector strategies future research to better characterise risk countries like Italy.
Protontherapy is a rapidly expanding radiotherapy modality where accelerated proton beams are used to precisely deliver the dose tumor target but generally considered ineffective against radioresistant tumors. Proton-Boron Capture Therapy (PBCT) novel approach aimed at enhancing biological effectiveness. PBCT exploits nuclear fusion reaction between low-energy protons and 11 B atoms, i.e. p+ B→ 3α (p-B), which supposed produce highly-DNA damaging α-particles exclusively across...
We report a case of Legionella pneumonia in dishwasher restaurant Rome, Italy, just after the end lockdown that was place to control SARS-CoV-2 epidemic. The highlights importance strict monitoring water and air systems immediately before reopening business or public sector buildings, need consider infections among differential diagnosis respiratory due ongoing COVID-19 pandemic.
Historically, several classification systems have been used for brachytherapy, and they were based on the type of clinical purpose, implant timing implant, dose-rate, loading treatment delivery. However, over last decades, there some major technological advancements, including introduction image-guidance possibility to modulate dose delivered, which led authors (in order highlight differences between old technique new approach) label it in a different way by replacing "brachytherapy" with...
The Erice 50 Charter titled "Strategies for Diseases Prevention and Health Promotion in Urban Areas" was unanimously approved at the conclusion of 50th Residential Course "Urban Health. Instruments promoting health assessing hygienic sanitary conditions urban areas", held from 29th March to 2nd April 2017 Erice, "Ettore Majorana" Foundation Centre Scientific Culture promoted by International School Epidemiology Preventive Medicine "G. D'Alessandro" Study Group "Building Hygiene" Italian...
Cancer spheroids are in vitro 3D models that became crucial nanomaterials science thanks to the possibility of performing high throughput screening nanoparticles and combined nanoparticle-drug therapies on models. However, most current spheroid analysis methods involve manual steps. This is a time-consuming process extremely liable variability individual operators. For this reason, rapid, user-friendly, ready-to-use, high-throughput image software necessary. In work, we report INSIDIA 2.0...
Interventional radiotherapy (IRT, brachytherapy) is a highly effective treatment method for non-melanoma skin cancer (NMSC). Traditionally, the maximum depth of NMSC lesions considered eligible contact IRT was 5 mm; however, following several national surveys and recent recommendations, such cut-off, thicker than mm may be treated by IRT. The use image guidance in defining actual treating to correctly identify clinical target volume (CTV) prevent unnecessary toxicity paramount importance....
Objective To better define the immunopathogenesis of COVID-19, present study aims to characterize early immune responses SARS-CoV-2 infection in household contacts COVID-19 cases. In particular, innate, T- and B-cell specific were evaluated over time. Methods Household cases screened for SARS−CoV−2 by nasopharyngeal swab surveillance purposes enrolled (T0, n=42). Of these, 28 subjects returned a follow-up test (T1). The innate response was assessed detecting panel soluble factors...
Interventional radiotherapy (brachytherapy) has become the new therapeutic standard in management of early stages nasal vestibule tumors; fact it allows for high local control rates and low toxicity profiles. However, since more patients will receive interventional as primary treatment, is desirable to implement novel strategies reduce dose organs at risk with future aim result further lowering long-term side effects.We were able identify two different treatment volume, including...
We report preventive measures adopted after tuberculosis (TB) transmission from a nurse to newborn assessed in late July 2011. All exposed neonates born between January and 2011 were clinically evaluated tested by QuantiFERON TB gold in-tube; newborns testing positive referred for prophylaxis. Of 1,340 newborns, 118 (9%) no other active cases of found. Active surveillance will be continued over the next three years all those exposed.
Graphene oxide (GO), a carbon-based nanomaterial, presents significant potential across biomedical fields such as bioimaging, drug delivery, biosensors, and phototherapy. This study examines the effects of integrating GO into poly(lactic-co-glycolic acid) (PLGA) scaffolds on human immune cell function. Our results demonstrate that high concentrations reduce viability peripheral blood mononuclear cells (PBMCs) following stimulation with anti-CD3 antibody. reduction extends to T lymphocyte...
AMA Placidi E, Fionda B, Rosa et al. Dosimetric impact of applying a model-based dose calculation algorithm for skin cancer brachytherapy (interventional radiotherapy). Journal Contemporary Brachytherapy. 2023;15(6):448-452. doi:10.5114/jcb.2023.134173. APA Placidi, E., Fionda, B., Rosa, Lancellotta, V., Napolitano, A., & De Angeli, M. (2023). Brachytherapy, 15(6), 448-452. https://doi.org/10.5114/jcb.2023.134173 Chicago Elisa, Bruno Enrico Valentina Antonio Martina and Francesco Pastore...