A5100638841- Ammonia Synthesis and Nitrogen Reduction
- Metabolomics and Mass Spectrometry Studies
- Pancreatic and Hepatic Oncology Research
- Cardiac Imaging and Diagnostics
- Food Allergy and Anaphylaxis Research
- Cancer, Hypoxia, and Metabolism
- Pancreatic function and diabetes
- Diet and metabolism studies
- Microbial Fuel Cells and Bioremediation
- Liver Disease Diagnosis and Treatment
- Advanced Photocatalysis Techniques
- Caching and Content Delivery
- Mast cells and histamine
- Mesenchymal stem cell research
- Cutaneous Melanoma Detection and Management
- Cancer Treatment and Pharmacology
- Peripheral Artery Disease Management
- Coronary Interventions and Diagnostics
- Allergic Rhinitis and Sensitization
- Endometrial and Cervical Cancer Treatments
- Pericarditis and Cardiac Tamponade
- Additive Manufacturing Materials and Processes
- Biochemical and Structural Characterization
- Remote Sensing in Agriculture
- Cell death mechanisms and regulation
Xiamen University
2020-2025
Central South University
2025
New Century International Hospital for Children
2025
Zhengzhou University
2025
Xi'an University of Architecture and Technology
2024
China Academy of Launch Vehicle Technology
2024
Xi'an Shiyou University
2023
Sichuan Cancer Hospital
2021
Center for Drug Evaluation and Research
2017-2020
Huazhong Agricultural University
2011-2020
The heat treatment was performed on the high speed laser-cladded Ni/316L coating to improve corrosion resistance. coatings were treated at temperatures of 650 °C, 700 750 °C and 800 respectively. results show that porosity independent annealing temperature chemical composition could be perfectly retained after treatment. grain size first decreased then increased with temperature. content equiaxed grains Fe19Ni precipitation phase increasing Due precipitation, resistance heat-treated higher...
Inhibitors of glycogen breakdown regulate glucose homeostasis by limiting production in diabetes. Here we demonstrate that restrained also inhibits cancer cell proliferation and induces apoptosis through oxidation, as well nucleic acid de novo fatty synthesis. Increasing doses (50–100 μ M) the phosphorylase inhibitor CP-320626 inhibited [1,2-13C2]glucose stable isotope substrate re-distribution among glycolysis, pentose synthesis MIA pancreatic adenocarcinoma cells. Limited oxidative...
Abstract An experiment was conducted to evaluate the effects of dietary supplementation a polysaccharide isolated from Astragalus membranaceus (APS) on performance and immune responses in weaned pigs. A total 144 crossbred pigs at 26 30 days age with an average initial live weight (LW) 7·64 (s.d. 0·290) kg were randomly allotted six diets supplemented APS 0, 100, 250, 500, 750, 1000 mg/kg. There replicates (three barrow pens three gilt pens) per diet treatment four pen. Pigs given food ad...
Soybean is a major protein source in human and animal nutrition, but has also been described as of allergenic reactions. The objective this study was to investigate anaphylactic reactions induced by purified soybean β-conglycinin 10-day old piglets, elaborate the molecular cellular mechanisms intestinal injury resulting from hypersensitivity. We investigated oral allergy syndrome piglets caused with an intragastric feeding protocol without using adjuvant. Physical symptoms, including...
Abstract As the most malignant tumor, prognosis of pancreatic cancer is not ideal even in small number patients who can undergo radical surgery. a highly heterogeneous chemotherapy resistance major factor leading to decreased efficacy and postoperative recurrence cancer. In this study, nuclear magnetic resonance (NMR)-based metabolomics was applied identify serum metabolic characteristics ductal adenocarcinoma (PDAC) screen potential biomarkers for its diagnosis. Metabolic changes with...
Abstract The renormalization group analysis has been proposed to eliminate secular terms in perturbation solutions of differential equations and thus expand the domain their validity. Here we extend method treat periodic orbits or limit cycles. Interesting normal forms could be derived through a generalization concept 'resonance', which offers nontrivial analytic approximations. Compared with traditional techniques such as multi-scale methods, current scheme proceeds very straightforward...
Pulmonary fibrosis seriously endangers human health, with its incidence and mortality rates steadily increasing. Current treatment methods have limitations. This review focused on the research progress future prospects of tangeretin in pulmonary fibrosis. Tangeretin, a compound derived from peel citrus fruits, has garnered attention due to unique chemical structure background traditional medical applications. paper discussed pathological mechanisms fibrosis, including initiation persistent...
Large to giant congenital melanocytic nevi (LGCMN) present clinical challenges due their complex phenotypic heterogeneity and increased melanoma risk. Molecular-level research is essential for understanding the pathogenic mechanisms of...
Abstract A polynomial scheme is proposed here to compute exact solutions of nonlinear partial differential equations (NPDEs) based on series expansions and a renormalization group (RG) related resummation. The most salient feature the current approach that only linear algebraic need be solved implement resummation for closed-form solution parameter dependence, which does not require any sophisticated analysis like Cole-Hopf transformation or Painlev'{e} test. New typical NPDEs are computed...
Abstract The objective of the present study was to characterize antigenic specificity purified soybean β-conglycinin and investigate its effects on growth immune responses rats. Thirty-two Brown Norway rats, 3 weeks age, were randomly allotted one four treatments individually fed casein-cornstarch based diets. Rats sensitised by means intragastric gavage with (0, 5, 10 or 20 mg protein/ml in phosphate buffered saline at pH 7.4) day 0, 7, 14, 21 (1 ml/animal). On 28, rats received a double...
Abstract Pancreatic ductal adenocarcinoma (PDAC) is characterized by high heterogeneity, and the postoperative prognosis of different patients often varies greatly. Therefore, classification pancreatic cancer precise treatment becomes particularly important. In our study, 1 H NMR spectroscopy was used to analyze 76 PDAC serum samples identify potential metabolic subtypes. The characteristics each subtype were screened out relationship between long‐term further identified. clinical stages did...
<i>Background:</i> The major storage protein in soybean seed is β-conglycinin and this has been identified as being responsible for food-allergic reactions several species. However, the mechanism through which induces an allergic reaction not yet elucidated. In addition, assessing antigenic activity of by studying a subunit rarely conducted. Therefore, objective present study was to characterize specificity α′-subunit. <i>Methods:</i> We established...
Comprehensive understanding of plasma metabotype diabetes mellitus (DM), coronary heart disease (CHD), and especially with (CHDDM) is still lacking. In this work, the metabolic differences links DM, CHD, CHDDM patients were investigated by strategy comparative metabolomics based on 1H NMR spectroscopy combined network analysis for revealing their differences. A total 17 metabolites are related to three diseases, among which valine, alanine, leucine, isoleucine, N-acetyl-glycoprotein...
Significance COP1 is an evolutionarily conserved ubiquitin ligase that plays a critical role in regulating the growth patterns of plants response to light. Light exposure promotes export from nucleus, preventing COP1-mediated degradation transcription factors regulate light-mediated development (photomorphogenesis). We report that, similar its regulation plants, mammalian localization modulated by environment signals. Inactivation key mitogen-activated protein kinase (MAPK) signaling pathway...
Antimicrobial genes are distributed in all forms of life and provide a primary defensive shield due to their unique broad-spectrum resistance activities. To better isolate these genes, we used the Bacillus subtilis expression system as host cells build Oryza rufipogon Griff cDNA libraries screen potential candidate from library at higher flux using built-in indicator bacteria. We observed that antimicrobial peptides OrR214 OrR935 have strong activity against variety Gram-positive...
To investigate the optimal anticoagulation methods and monitoring strategy for Chinese patients undergoing heart valve replacement, which is potentially quite different from western populations.In this multicenter prospective cohort study, data was acquired 25 773 in-hospital in 35 medical centers 20 519 outpatient clinic 11 January 1st, 2011 to December 31th, 2015.As patients, mean age of study population (48.6±11.2) years old; main etiology pathology rheumatic (87.5%) origin among cohort;...