A5081022483- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging and Pathology Studies
- Lung Cancer Treatments and Mutations
- COVID-19 diagnosis using AI
- Osteoarthritis Treatment and Mechanisms
- Foreign Body Medical Cases
- Lung Cancer Diagnosis and Treatment
- Esophageal and GI Pathology
- Viral Infections and Immunology Research
- Extracellular vesicles in disease
- Cancer-related Molecular Pathways
- Sepsis Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Ubiquitin and proteasome pathways
- Inflammatory mediators and NSAID effects
- Microtubule and mitosis dynamics
- Tracheal and airway disorders
- Tuberculosis Research and Epidemiology
North China University of Science and Technology Affiliated Hospital
2020
Xiamen University
2015-2017
Although emerging evidence has indicated that single nucleotide polymorphisms (SNPs) in microRNAs (miRNAs) are associated with susceptibility to gastric cancer, a limited number of studies have revealed the underlying molecular mechanisms. In present study, results suggested miR-1269a rs73239138 role decreasing risk cancer. The level variant expression was significantly downregulated compared wild-type cells (Fig. 1). Furthermore, overexpression inhibited apoptosis cancer cells. Expression...
Oxaliplatin-based chemotherapy is a primary treatment for patients with metastatic colorectal cancer (CRC); however, its efficacy limited. Therefore, novel therapeutic agents are urgently required. MLN4924 first‑in‑class inhibitor of neural precursor cell expressed, developmentally downregulated 8 (NEDD8)‑activating enzyme E1, and has entered various phase‑I/II clinical trials therapy due to significant anticancer efficacy. The aim the present study was examine synergistic effect underlying...
Background CAP is the most common cause of death in infectious diseases developing countries, while also an important and morbidity developed countries. In recent years, CURB-65 (or CRB-65) pneumonia severity index (PSI) scoring systems have been widely used prognosis system CAP. However, each them has some shortcomings predicting ICU admission patients. The aim this study to analyze serum inflammatory biomarkers combined age established a new prediction model Methods This retrospective...
Abstract Background Tracheobronchial foreign body aspiration is a potentially risky medical event, while the condition often requires early detection and rapid intervention to improve respiratory symptoms prevent major morbidity. Notably, bodies may not be identified they are likely mistaken for neoplastic lesions. However, CEA, as one of tumor markers, presents available assisting in lung cancer diagnosis, especially non–small‐cell cancer, specificity CEA high. Methods Here, we described...
Background Chest CT is widely used in clinical diagnosis and efficacy evaluation of CAP. While repeated chest examinations to evaluate dynamic changes images a short period time common phenomenon, it causes lot waste medical resources, due the large dose radiation, can cause some harm human body. The purpose this study establish new model predict image CAP patients by analyzing age, smoking history, serum inflammatory markers. Methods This retrospective study. All had received scan indexes...