- Infection Control and Ventilation
- COVID-19 epidemiological studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Treatment of Major Depression
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastric Cancer Management and Outcomes
- Animal Genetics and Reproduction
- Esophageal and GI Pathology
- Chromosomal and Genetic Variations
- Organ Transplantation Techniques and Outcomes
- Gallbladder and Bile Duct Disorders
- Building Energy and Comfort Optimization
- Animal Disease Management and Epidemiology
- Electrochemical sensors and biosensors
- Dental Radiography and Imaging
- Virus-based gene therapy research
- Reproductive biology and impacts on aquatic species
- Body Contouring and Surgery
- Spinal Fractures and Fixation Techniques
- Immunotoxicology and immune responses
- Parvovirus B19 Infection Studies
- Perfectionism, Procrastination, Anxiety Studies
- Inflammatory Biomarkers in Disease Prognosis
- Genetic and Kidney Cyst Diseases
- COVID-19 impact on air quality
Guangdong Ocean University
2023-2025
Beijing University of Civil Engineering and Architecture
2024-2025
Sixth Affiliated Hospital of Sun Yat-sen University
2024
Sun Yat-sen University
2024
Nanjing University of Aeronautics and Astronautics
2023-2024
Xijing Hospital
2024
Air Force Medical University
2024
First Affiliated Hospital of Xi'an Jiaotong University
2020-2024
Xi'an Jiaotong University
2024
First People's Hospital of Yunnan Province
2023
To accomplish concerted physiological reactions, nature has diversified functions of a single hormone at least two primary levels: 1) Different receptors recognize the same hormone, and 2) different cellular effectors couple to hormone–receptor pair [R.P. Xiao, Sci STKE 2001 , re15 (2001); L. Hein, J. D. Altman, B.K. Kobilka, Nature 402 181–184 (1999); Y. Daaka, M. Luttrell, R. Lefkowitz, 390 88–91 (1997)]. Not only these questions lie in heart actions receptor signaling but also dissecting...
Fish species of the family Scatophagidae possessing known candidate sex-determining genes (male-specific dmrt1Ys), offer suitable models for studying sex chromosome evolution. Here, we analyzed turnover events in three representative fish Scatophagidae, belonging to genera Scatophagus and Selenotoca, which diverged 12.8 million years ago (Mya). Prior divergence Sc. argus tetracanthus 7.2 Mya, their dmrt1Y was differentiated from its locus, truncated dmrt1ΔX, through allelic variation. The Y...
Epidemics are dangerous and difficult to prevent control, especially in urban areas. Clarifying the correlation between COVID-19 Outbreak Frequency spatial environment may help improve cities’ ability respond such public health emergencies. In this study, we firstly analyzed distribution characteristics of by correlating geographic locations epidemic-affected neighborhoods city Beijing with time point onset. Secondly, created a geographically weighted regression model combining external...
Abstract Portable air cleaners (PACs) have shown promising potential in reducing the risk of SARS-CoV-2 infection by effectively removing pollutant particles and optimizing airflow patterns. This study focused on a simulated scenario where an infected source susceptible person engage conversation within naturally ventilated room. By combining Eulerian fluid method with Lagrangian particle tracking model, comprehensive insight into indoor patterns dispersion virus-laden droplets was gained....
The dispersion of respiratory droplets is strongly influenced by the complex airflow induced human activities, such as walking in a queue. Understanding relationship between local disturbances during queue and droplet crucial. This study investigates effects following distance (1.0, 1.5, 2.0, 2.5 m), speed (0.8, 1.0, 1.2, 1.4 m/s), diameter (1, 10, 50, 80, 120 μm) on dispersion. findings reveal that interaction wake vortex forward provides foundation for cross-infection among individuals. An...
Abstract: Damage to the abdominal aortic wall and local inflammatory response are key factors resulting in aneurysm (AAA) formation. During this process, macrophage polarization plays a role. However, AAA, regulatory mechanism of macrophages is still unclear, further research needed. In study, we found that transcription factor TCF3 was expressed at low levels AAA. We overexpressed could inhibit MMP expression promote M2 polarization, thereby inhibiting progression Knocking down M1...
This study presents an innovative physical isolation measure for commercial scenarios, namely, hanging curtains, to prevent the spread of respiratory infections. Using computational fluid dynamics simulation techniques, closed spaces within cruise cabins were modeled and numerically analyzed, focusing on dispersion characteristics droplets. Additionally, orthogonal methods employed investigate various arrangements curtains their effects droplet based spatial positioning. The research...
Pulmonary nodules (PNs) with a diameter from 5 to 10 mm exhibit malignancy rates anywhere 47.5 61.5%. Despite the potential danger posed by these lesions, their small size makes biopsy of sub-centimetre (≤ mm) PNs under computed tomography (CT) guidance very difficult.A meta-analysis was performed goal evaluating safety and diagnostic utility CT-guided procedures for PNs.Relevant studies published through April 2023 were identified in PubMed, Web Science, Wanfang databases used conduct...
Acute severe hepatitis with unknown aetiology in children (ASHep-UA) has become a global health alert. This article reported clinicopathological characteristics of 3 probable ASHep-UA cases.We respectively collected serological data and liver biopsies suspected cases ASHep-UA. Neutralizing antibodies titer for acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants were determined by virus neutralization test (VNT). Histological assessment, immunohistochemistry (IHC)...
The spotted scat (Scatophagus argus) is an important ornamental species with sexually biased values that favor males. Therefore, it makes sense to breed mono-male fingerlings as fish. has XX/XY sex determination system; therefore, the first step in producing genetically all-male offspring should be induction of a fertile sex-reversed XY pseudo-female, which would then mated normal male produce YY super-male. However, pseudo-female produced by estradiol (E2) treatment failed due ovarian...
Nanomedicines have emerged as a potent anti-tumor strategy with tremendous progress. However, complex structure of integrating different or even opposing nanoproperties into one nanomedicine to improve overall delivery efficiency after intravenous injection hampers clinical translation. Cell membrane-coated biomimetic nanomedicines (CMC-BNs) been considered rationally designed next-generation high therapeutic efficacy, among which blood cell-derived cellular nanosponges (CTI-005) and...
<title>Abstract</title> With known candidate sex-determining genes (male-specific dmrt1Ys), fish species of the family Scatophagidae are good models for studying sex chromosome evolution. Here, we analyzed turnover events in three representative from two genera that have diverged 12.8 million years ago (Mya). Scatophagus argus and Sc. tetracanthus possess dmrt1Ys arose allelic variation before they 7.2 Mya, their loci truncated dmrt1ΔX. The Y (Chr1) is result fusion original (Chr4) with an...