- Dental Health and Care Utilization
- Orthodontics and Dentofacial Orthopedics
- Irish and British Studies
- Dental Erosion and Treatment
- Oral microbiology and periodontitis research
- Dental Research and COVID-19
- Dental materials and restorations
- Fluoride Effects and Removal
- Temporomandibular Joint Disorders
- Translation Studies and Practices
- Dental Education, Practice, Research
- dental development and anomalies
- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Anatomy and Medical Technology
- Cleft Lip and Palate Research
- Disaster Management and Resilience
- Shoulder Injury and Treatment
- Diverse Aspects of Tourism Research
- Anesthesia and Pain Management
- Dental Trauma and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Orthopedic Surgery and Rehabilitation
- Nutrition and Health in Aging
- Pharmacological Effects of Medicinal Plants
University College Cork
2016-2025
Princeton University
2025
Boston University
2021-2024
Sorbonne Université
2024
University College London
2006-2024
Assistance Publique – Hôpitaux de Paris
2024
University School
2023-2024
Takeda (United States)
2023
Marymount University
2023
University of Chicago
2019-2021
BackgroundFemoroacetabular impingement syndrome is an important cause of hip pain in young adults. It can be treated by arthroscopic surgery, including reshaping the hip, or with physiotherapist-led conservative care. We aimed to compare clinical effectiveness arthroscopy best care.MethodsUK FASHIoN a pragmatic, multicentre, assessor-blinded randomised controlled trial, done at 23 National Health Service hospitals UK. enrolled patients femoroacetabular who presented these hospitals. Eligible...
Congenital thrombotic thrombocytopenic purpura (TTP) results from severe hereditary deficiency of ADAMTS13. The efficacy and safety recombinant ADAMTS13 standard therapy (plasma-derived products) administered as routine prophylaxis or on-demand treatment in patients with congenital TTP is not known.
Seminal viral load is likely to be directly related the sexual transmissibility of human immunodeficiency virus type 1 (HIV-1). However, it not clear whether level HIV-1 in semen varies with stage infection and antiretroviral therapy reduces seminal load. A nucleic acid sequence-based amplification (NASBA) technique was used quantify RNA as an indicator infectious blood plasma homosexual men different stages durations infection. The median a cross section 34 11,000 copies/ml (range, <400...
A number of quantitative assays have been developed by using amplification techniques to measure human immunodeficiency virus type 1 RNA in the plasma infected individuals. The Virology Committee AIDS Clinical Trials Group Division AIDS, National Institute Allergy and Infectious Diseases, has established a quality assurance program (QAP) for HIV-1 levels plasma. primary objective QAP was ascertain that laboratory could maintain precision required 90% power detect fivefold difference copy...
The aims of this study were to estimate the average maximum mouth opening and range in a representative sample Irish adult population, compare patients with without signs or symptoms temporomandibular joint (TMJ) dysfunction syndrome investigate association between stature among populations. As part National Survey Adult Oral Health, was measured questionnaire data collected for 1513 adults, aged 16-99 years. 43 mm males 41 females. Mouth found reduce age, independent gender. No link reduced TMJ
A key trend of recent literature is the increased use interorganizational relationships to achieve organizational objectives. While phenomenon collaborative innovation has attracted significant academic interest in years, little research been undertaken examine how widespread relative size or diversity partner organizations being leveraged for activity. Consequently, this paper seeks address two questions. Firstly, extent which occurring within different sized firms that are and development...
ABSTRACT Mass casualty triage is the process of prioritizing multiple victims when resources are not sufficient to treat everyone immediately. No national guideline for mass exists in United States. The lack a has resulted variability processes, tags, and nomenclature. This potential inject confusion miscommunication into disaster incident, particularly jurisdictions involved. Model Uniform Core Criteria Casualty Triage were developed be ensure interoperability standardization responding...
To define the optimal blood collection parameters for plasma human immunodeficiency virus type 1 (HIV-1) viral load testing, HIV-1 RNA levels were quantitated with NASBA QT System from specimens that collected, processed, and stored under a variety of conditions might have affected stability. We determined when whole was processed within 2 h specimen detected in EDTA-, heparin-, acid citrate dextrose (ACD)-anticoagulated samples comparable. The serum (mean = 4.126 log units) significantly...
Abstract Background Childhood obesity is emerging as a major public health problem in developed and developing countries worldwide. The aim of this survey was to establish baseline data on the prevalence correlates overweight among children adolescents Republic Ireland (RoI) Northern (NI). Methods heights weights 19,617 school-going aged between 4 16 years NI RoI were measured using standardised calibrated scales measures. participants representative cross-sectional sample randomly selected...
Abstract Cadaveric material has long been used to teach anatomy and more recently train students in clinical skills. The aim of this study was develop a systematic approach compare the impact four embalming solutions on tissues human cadavers. To end, formalin‐based solution, Thiel, Genelyn Imperial College London soft‐preservation (ICL‐SP) solution were compared. effect these chemicals properties tissue assessed by measuring range motion (ROM) joints dimensions different structures computed...
ABSTRACT We compared whole blood dried on filter paper to the standard assay with frozen cell-free plasma for use in quantitation of human immunodeficiency virus RNA load blood. values from paper, corrected hematocrit, gave results comparable those terms sensitivity and reproducibility.
Abstract Background As the world population ages, requirement for cost‐effective methods of treating chronic disease conditions increases. In terms oral health, there is a rapidly increasing number dentate elderly with high burden maintenance. Population surveys indicate that older individuals are keeping their teeth longer and higher caries risk group. Atraumatic Restorative Treatment ( ART ) could be suitable patients in nursing homes or house‐bound elderly, but very little research has...
doi: 10.1111/j.1741‐2358.2011.00579.x Impact of tooth replacement strategies on the nutritional status partially‐dentate elders Objective: To investigate impact partially dentate older patients, and, to compare two different strategies; conventional treatment using removable partial dentures and functionally orientated based shortened dental arch. Background: Amongst diet plays a key role in disease prevention, as poor diets have been linked numerous illnesses. Poor oral health loss teeth...
Abstract Objective To conduct a cost‐effectiveness analysis comparing two different tooth replacement strategies for partially dentate older patients, namely partial removable dental prostheses ( RDP ) and functionally orientated treatment based on the shortened arch concept SDA ). Methods Ninety‐two patients completed randomized controlled clinical trial. Patients were randomly allocated to groups: group group. Treatment effect was measured using impact oral health–related quality of life...