A5100410356- Nanoplatforms for cancer theranostics
- Bone Tissue Engineering Materials
- Nanoparticle-Based Drug Delivery
- Advanced Photocatalysis Techniques
- X-ray Diffraction in Crystallography
- Advanced Nanomaterials in Catalysis
- Crystallization and Solubility Studies
- Collagen: Extraction and Characterization
- Arsenic contamination and mitigation
- Diamond and Carbon-based Materials Research
- Photodynamic Therapy Research Studies
- Advanced biosensing and bioanalysis techniques
- Gas Sensing Nanomaterials and Sensors
- RNA Interference and Gene Delivery
- Photoacoustic and Ultrasonic Imaging
- Marine and coastal ecosystems
- Extracellular vesicles in disease
- Heavy metals in environment
- Nanocluster Synthesis and Applications
- Selenium in Biological Systems
- Karst Systems and Hydrogeology
- Graphene and Nanomaterials Applications
- Pigment Synthesis and Properties
- Heme Oxygenase-1 and Carbon Monoxide
- Ultrasound and Hyperthermia Applications
Hainan University
2023-2025
Ministry of Education of the People's Republic of China
2023-2024
Jinan University
2011-2024
Nanjing Tech University
2024
North China University of Technology
2024
Fujian Agriculture and Forestry University
2023-2024
Hunan University of Traditional Chinese Medicine
2024
PLA 306 Hospital
2024
Sorbonne Université
2024
University College London
2024
Congenital thrombotic thrombocytopenic purpura (TTP) results from severe hereditary deficiency of ADAMTS13. The efficacy and safety recombinant ADAMTS13 standard therapy (plasma-derived products) administered as routine prophylaxis or on-demand treatment in patients with congenital TTP is not known.
The cationic composition engineering is conducted in XLaLiTeO 6 :Eu 3+ (X = Ba, Sr, Ca, and Mg), leading to the high quantum efficiency of MgLaLiTeO , optimization mechanism provides baselines for high-quality Eu doped phosphors.
Astragaloside IV (AS-IV) exhibits diverse biological activities. Despite this, the detailed molecular mechanisms by which AS-IV ameliorates diabetic nephropathy (DN) and shields podocytes from oxidative stress (OS) mitochondrial dysfunction remain poorly understood. In this study, we used biochemical assays, histopathological analysis, Doppler ultrasound, transmission electron microscopy，flow cytometry, fluorescence staining, Western blotting other methods. was administered to db/db mice for...
Integrated imaging techniques offer enhanced medical insights into the central nervous system by combining different modalities. In glioma diagnosis, challenge often lies in delivering contrast agents effectively across blood-brain barrier. We present an integrated multimodal biohybrid, GV@pCY5, which enables barrier penetrating as well fluorescence and ultrasound (FL/US) capabilities. This biohybrid is created decorating a far-red-fluorescent cyanine dye (CY5) onto polyethyleneimine...
Abstract Macrophage-derived foam cells are a major component of atherosclerotic plaques and have an important role in the progression plaques, thus posing great threat to human health. Photodynamic therapy (PDT) has emerged as therapeutic strategy for atherosclerosis. Here, we investigated effect PDT mediated by upconversion fluorescent nanoparticles encapsulating chlorin e6 (UCNPs-Ce6) on cholesterol efflux THP-1 macrophage-derived explored possible mechanism this effect. First, found that...
This study employed adaptive laboratory evolution to improve the acid tolerance of Lactiplantibacillus plantarum, a vital strain in food fermentation and potential probiotic. Phenotype genomic analyses identified overexpression stress response proteins, ATP synthases, transporters as pivotal conferring evolved strains. These adaptations led shorter lag phase, improved survival rates, higher intracellular pH values compared wild-type under conditions. Additionally, strains showed an increased...
Abstract This article is based on the conceptual-thermodynamic design and exergoeconomic investigation of a new poly-generation system driven by biomass fuel (i.e. wood). In proposed energy system, Rankine power process, gasification desalination process multi-effect desalination, MED) water electrolyzer solid oxide cell, SOEC) are installed in hybrid form. Electric energy, fresh hydrogen gas useful output products system. The indicates an innovative framework for carbon-free production...
Reconstruction of bone defects remains a clinical challenge, and 3D bioprinting is fabrication technology to treat it via tissue engineering. Collagen currently the most popular cell scaffold for engineering; however, shortage printability low mechanical strength limited its application bioprinting. In study, aiding with gelatin support bath, collagen-based was fabricated printing, where hydroxyapatite (HAP) marrow mesenchymal stem cells (BMSCs) were added mimic composition bone. The results...
Oriented fibers in bone lamellae are recognized for their contribution to the anisotropic mechanical performance of cortical bone. While increasing evidence highlights that such oriented also exhibit osteogenic induction preosteoblasts, little is known about effect overlay angle between on differentiation marrow-derived mesenchymal stem cells (BMSCs). In this study, lamellae-like fibrous matrices composed aligned core–shell [core: polycaprolactone (PCL)/type I collagen (Col I) + shell: Col...
To investigate the sonoactivity of hypericin (HY), together with its sonodynamic effect on THP-1 macrophages and underlying mechanism.CCK-8 was used to examine cell viability. Confocal laser scanning microscopy performed assess localization HY in cells, reactive oxygen species (ROS) generation, opening mitochondrial permeability transition pore (mPTP) after different treatments. Apoptosis analyzed using Hoechst-propidium iodide transmission electron microscopy. Mitochondrial membrane...
The seagrass Zostera marina is a monocotyledonous angiosperm belonging to polyphyletic group of plants that can live submerged in marine habitats. L. one the most common seagrasses and considered cornerstone plant molecular ecology research comparative studies. However, mechanisms underlying its adaptation environment still remain poorly understood due limited transcriptomic genomic data.Here we explored transcriptome Z. leaves under different environmental conditions using Illumina...
Iron (Fe) is necessary for plant growth and development. The mechanism of uptake translocation in Cadmium (Cd) similar to iron, which shares iron transporters. Yellow stripe-like transporter (YSL) plays a pivotal role transporting other metal ions plants. In this study, MsYSL6 its promoter were cloned from leguminous forage alfalfa. transient expression MsYSL6-GFP indicated that was localized the plasma membrane cytoplasm. induced alfalfa by deficiency Cd stress, further proved GUS activity...
BACKGROUND Several studies have reported that the walking trail making test (WTMT) completion time is significantly higher in patients with developmental coordination disorders and mild cognitive impairments. We hypothesized WTMT performance would be altered older adults white matter hyperintensities (WMH). AIM To explore people WMH. METHODS In this single-center, observational study, 25 elderly WMH admitted to our hospital from June 2019 2020 served as group 20 participants matched for age,...
Abstract Background As a small G protein of Ras family, Ras-like-without-CAAX-1 (RIT1) plays critical role in various tumors. Our previous study has demonstrated the involvement RIT1 promoting malignant progression hepatocellular carcinoma (HCC). However, its underlying mechanism remains unclear. Methods Gene set enrichment analysis (GSEA) was conducted TCGA LIHC cohort to investigate biological RIT1. Live cell imaging, immunofluorescence (IF) and flow cytometry assays were used verify...