- Dental materials and restorations
- Bone Tissue Engineering Materials
- Orthopaedic implants and arthroplasty
- Dental Implant Techniques and Outcomes
- Endodontics and Root Canal Treatments
- biodegradable polymer synthesis and properties
- Dental Erosion and Treatment
- Dental Research and COVID-19
- Hydrogels: synthesis, properties, applications
- Electrospun Nanofibers in Biomedical Applications
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Graphene and Nanomaterials Applications
- 3D Printing in Biomedical Research
- Bone fractures and treatments
- Periodontal Regeneration and Treatments
- Additive Manufacturing and 3D Printing Technologies
- Calcium Carbonate Crystallization and Inhibition
- Advanced materials and composites
- Dental Radiography and Imaging
- Antimicrobial agents and applications
- Advanced Polymer Synthesis and Characterization
- Hip and Femur Fractures
- Concrete and Cement Materials Research
- Bone and Dental Protein Studies
King's College London
2014-2023
Guy's Hospital
2014-2023
Transnational Press London
2015
St Thomas' Hospital
2006-2012
University of Ulster
2012
Virginia Tech
2011
Population Council
2009
University of Dental Medicine
2001-2009
The London College
2009
University of London
1994-2008
Polymers with eugenol moieties covalently bonded to the macromolecular chains were synthesized for potential application in orthopedic and dental cements. First, was functionalized polymerizable groups. The synthetic methods employed afforded two different methacrylic derivatives, where acrylic either directly bonded, eugenyl methacrylate (EgMA), or separated through an oxyethylene group, ethoxyeugenyl (EEgMA). A typical Fisher esterification reaction used synthesis of EgMA EEgMA, affording...
Tissue engineering–based bone grafts are emerging as a viable alternative treatment modality to repair and regenerate tissues damaged result of disease or injury. The choice the biomaterial component is critical determinant success graft scaffold; essentially, it must induce allow native tissue integration, most importantly mimic hierarchical structure bone. Calcium phosphate bioceramics widely used in orthopaedics dentistry applications due their similarity mineral ability favourable...
Alginates are attractive in tissue regeneration due to their similarity the extracellular matrix, biocompatibility, biodegradability, non-antigenicity, and ability undergo ionotropic gelation. Alginate hydrogels formed by ionic crosslinking mainly using calcium ions with some reports on use of strontium zinc ions. Strontium trace amounts known accelerate bone healing role regulating osteoblasts osteoclasts addition antibacterial properties. This study effect forming alginate hydrogel films...
This is a proof of principle report showing that fibres Bioglass 45S5 can form biocompatible scaffold to guide regrowing peripheral axons in vivo. We demonstrate cultured rat Schwann cells and fibroblasts grow on vitro using SEM immunohistochemistry, provide qualitative quantitative evidence axonal regeneration through Silastic conduit filled with vivo (across 0.5 cm interstump gap the sciatic nerves adult rats). Axonal regrowth at 4 weeks indistinguishable from which occurs across an...
Second to autologous bone grafts are the calcium phosphate cements (CPCs) used as synthetic substitutes due their chemical similarity mineral component of bone. Their ability conform complex defects and excellent osteoconductivity also render them scaffolds for tissue engineering, although they do have own limitations. Calcium phosphates can be divided into two main categories, namely apatite brushite. Apatites exhibit low solubility, whereas, that set form brushite, metastable, which...
The last decade has seen a variety of modifications glass-ionomer cements (GICs), such as inclusion bioactive glass particles and dispensing systems. Hence, the aim was to systematically evaluate effect mixing modes presence reactive additives on physical properties several GICs.The eight commercial restorative GICs; Fuji IX GP Extra (C&H), KetacTM Fill Plus Applicap II LC Glass Carbomer Cement Equia® Forte Fil, capsulated versus manually mixed were assessed. 256 cylindrical specimens...