Godshelp Osas Egharevba

ORCID: 0000-0001-5016-0289
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Research Areas
  • Metal-Organic Frameworks: Synthesis and Applications
  • Synthesis and biological activity
  • Natural Antidiabetic Agents Studies
  • Cannabis and Cannabinoid Research
  • Quantum Mechanics and Non-Hermitian Physics
  • Quantum chaos and dynamical systems
  • Advanced Photocatalysis Techniques
  • Bioactive natural compounds
  • Advanced Nanomaterials in Catalysis
  • Sperm and Testicular Function
  • Phytochemicals and Antioxidant Activities
  • Nanocomposite Films for Food Packaging
  • Bioactive Compounds and Antitumor Agents
  • Covalent Organic Framework Applications
  • Nigella sativa pharmacological applications
  • GABA and Rice Research
  • Advanced Chemical Physics Studies
  • Nanoplatforms for cancer theranostics
  • Catalytic Processes in Materials Science
  • Nanoparticles: synthesis and applications
  • Drug-Induced Hepatotoxicity and Protection
  • Seed and Plant Biochemistry
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Insect Pest Control Strategies
  • Nonlinear Waves and Solitons

Landmark University
2019-2025

Redeemer's University
2022

Indian Institute of Chemical Technology
2019

University of Hyderabad
2019

Cancer, a major health challenge worldwide, is accountable for large percentage of disease-related deaths. Annually, new cancer diagnosis reaches over 10 million with record about 9.6 deaths....

10.1039/d4ma00425f article EN cc-by-nc Materials Advances 2025-01-01

The increase in demand for agricultural produce necessitates the continuous search affordable, ecofriendly, readily available crop protectors, and food preservatives. Historically, use of various chemicals was employed controlling plant diseases to maintain quality. In past few decades, several natural product-based alternatives have been discovered projected as better synthetic pesticides other agrochemicals. Recent studies focusing on application different botanicals protection...

10.1155/2020/8840046 article EN cc-by International Journal of Agronomy 2020-07-30

A series of 2-anilinopyridyl linked benzothiazole-hydrazone conjugates (<bold>5a-aa</bold>) were designed, synthesized and evaluated for their anticancer potential.

10.1039/c8nj06517a article EN New Journal of Chemistry 2019-01-01

AimsPlant extracts have long been used for the ethnomedical treatment of diabetes, microbial infections and as a source antioxidant. This study was aimed at investigating antidiabetic, antioxidant, antimicrobial activities n-hexane ethyl acetate extract Tephrosia bracteolata leaves (TBL) associated with ethnobotanical knowledge local people Nigeria.Main methodsThe phytochemical composition T. were determined following standard procedures in literature, it's vitro inhibitory against...

10.1016/j.heliyon.2019.e02275 article EN cc-by-nc-nd Heliyon 2019-08-01

A shifted Morse potential model is modified to fit the study of vibrational energies some molecules. Using a traditional technique/methodology, energy and un-normalized radial wave functions were calculated for model. The condition that fits molecular description deduced together with expression screening parameter. SiC, NbO, CP, PH, SiF, NH Cs2 molecules computed by inserting their respective spectroscopic constants into equation. It was shown results all agreement perfectly experimental...

10.1038/s41598-022-19179-4 article EN cc-by Scientific Reports 2022-09-07

A mini survey was employed in the search of herbs and spices which people believe could prevent them from contracting COVID-19. Phytochemicals have been earlier implicated for bioactivity afore-mentioned were identified through literature search. The phytochemicals then subjected to pharmacore modelling, molecular docking dynamics simulation order identify that serve as inhibitors 3-Chymotryprin-like protease RNA dependent-RNA polymerase SARS-CoV-2. drug-likeness toxicity profile afterwards...

10.1080/07391102.2021.2024883 article EN Journal of Biomolecular Structure and Dynamics 2022-01-07

The preliminary phytochemical investigation of n-hexane, ethyl acetate and methanol extracts Thaumatococcus daniellii leaves revealed the presence fats oils, terpenoids, flavonoids, steroids glycosides. antimicrobial tests against some strains bacteria fungi showed inhibitions at moderate to high concentrations. Methanol extract plant exhibited low 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity with IC50 615.14 μg/ml. Gas chromatography-mass spectrometry (GC-MS)...

10.4314/ijs.v19i2.21 article EN Deleted Journal 2017-11-14

The development of an effective and affordable malaria treatment drug is required to reduce the number deaths caused by this disease around world. in-vivo anti-malarial activities Cannabis were investigated, as well in-silico antimalarial prediction cannabis GC–MS compounds. Thirty albino mice divided into six groups five animals each at random: A, B, C, D, E F. in all except normal control group infected with Plasmodium berghei NK-65 before commencement treatment. Each was treated...

10.1016/j.sciaf.2022.e01108 article EN cc-by-nc-nd Scientific African 2022-01-31

Abstract Novel 1,1-diaryl vinyl-sulfones analogues of combretastatin CA-4 were synthesized via Suzuki–Miyaura coupling method and screened for in-vitro antiproliferative activity against four human cancer cell lines: MDA-MB 231(breast cancer), HeLa (cervical A549 (lung IMR-32 (neuroblast along with a normal line HEK-293 (human embryonic kidney cell) by employing 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay. The compounds synthesised had better cytotoxicity the...

10.1038/s41598-022-05958-6 article EN cc-by Scientific Reports 2022-02-03

Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity data on the medicinal effects cannabis fertility. This study evaluated testicular function and quality modulation with in rats.Twenty-five Wistar rats were randomly grouped into five: A, B, C, D, each group have 5 rats. A (control): 0.2 ml 2% DMSO, B (vitamin C): 90 mg/kg body weight, E administered: mg/kg, 10 20 weight ethanolic leaf extract (ELEC) respectively. The...

10.1186/s12906-022-03704-z article EN cc-by BMC Complementary Medicine and Therapies 2022-08-26

The solution of the radial Schrödinger equation for modified shifted Morse potential model is obtained using an approximate supersymmetric approach. two different formulae computation centrifugal distortion constant are clearly examined to deduce formula that gives result perfectly aligns with experimental data. Numerical values molecules computed (dissociation energy) from equations. ground state energy spectra Herzberg's level as a standard some molecules. results compared and Our study...

10.1016/j.heliyon.2023.e13526 article EN cc-by-nc-nd Heliyon 2023-02-01

The solutions for Morse potential energy function under the influence of Schr¨odinger equation are examined using supersymmetric approach. obtained was used to generate eigenvalues forX1 +state scandium monoiodide (ScI) and X3 state nitrogen (NI) respectively were by imputing their respective spectroscopic parameters. calculated results two molecules aligned excellently with predicted/observed values.

10.46481/jnsps.2021.407 article EN cc-by Journal of the Nigerian Society of Physical Sciences 2021-11-29

Despite advancement in technology and healthcare delivery, infectious diseases still ravage humanity, plants-based remedies remain our major kick back against them. The phytochemical screening, antimicrobial, antioxidant, anti-hyperglycemic activities of n-hexane, ethyl acetate, methanolic extracts Senecio abyssinicus leaves were investigated this study, line with SDG 3, 9 12 goals, following standard methods. vitro antioxidant properties tested using 2,2-diphenyl-1-picrylhydrazyl (DPPH)...

10.4314/jasem.v27i5.8 article EN cc-by Journal of applied science and environmental management 2023-05-31
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