A5047890005- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Bacterial biofilms and quorum sensing
- Viral gastroenteritis research and epidemiology
- Cannabis and Cannabinoid Research
- Mycobacterium research and diagnosis
- Salmonella and Campylobacter epidemiology
- Computational Drug Discovery Methods
- Postharvest Quality and Shelf Life Management
- Sperm and Testicular Function
- Malaria Research and Control
- Iron Metabolism and Disorders
- Fermentation and Sensory Analysis
- GABA and Rice Research
- Galectins and Cancer Biology
- Garlic and Onion Studies
- Botanical Research and Applications
- Diverse Scientific Research Studies
- Biosensors and Analytical Detection
- Toxin Mechanisms and Immunotoxins
- Bacteriophages and microbial interactions
- Fungal Infections and Studies
- Cholinesterase and Neurodegenerative Diseases
- Image Processing Techniques and Applications
- Digital Imaging for Blood Diseases
Landmark University
2013-2022
Elizade University
2022
University of Nottingham
2008-2015
University of Jos
2012-2013
Jos University Teaching Hospital
2012
Neurodegenerative diseases, for example Alzheimer’s, are perceived as driven by hereditary, cellular, and multifaceted biochemical actions. Numerous plant products, flavonoids, documented in studies having the ability to pass blood-brain barrier moderate development of such illnesses. Computer-aided drug design (CADD) has achieved importance discovery world; innovative developments aspects structure identification characterization, bio-computational science, molecular biology have added...
In 2018, an estimated 1.8 million persons living in Nigeria had HIV infection (1.3% of the total population), including 1.1 (64%) who were receiving antiretroviral therapy (ART) (1).Effective ART reduces morbidity and mortality rates among with prevents transmission once viral load is suppressed to undetectable levels (2,3).In April 2019, through U.S. President's Emergency Plan for AIDS Relief (PEPFAR),* CDC launched 18-month Surge program nine Nigerian states rapidly increase number ART.CDC...
Staphylococcal toxicity and antibiotic resistance (STAAR) have been menacing public health. Although vancomycin-resistant Staphylococcus aureus (VRSA) is currently not as widespread methicillin-resistant S. (MRSA), genome evolution of MRSA into VRSA, including strains engineered within the same patient under anti-staphylococcal therapy, may build up to future health concern. To further complicate diagnosis, infection control anti-microbial chemotherapy, non-sterile sites such nares skin...
Enteric fever is an invasive bacterial infection mostly caused by Salmonella enterica serovar Typhi, which a common agent of enteric fever. This illness has been major public health issue, as it affects large number individuals globally. The box-plot analytic method involved in exploratory data analysis using statistical techniques to identify patterns that may be hidden group numbers used visually summarize and compare groups data. We evaluted the effect on various haematologic parameters...
Background:Low hemoglobin (Hb) and iron deficiency among child bearing females have been linked to decreased immune system function, impaired cognitive functioning complications in pregnancy.
Type-2 diabetes mellitus (T2DM), is considered being a multifaceted disorder that presents major therapeutic problem. Despite the widespread efforts in managing T2DM, drug discovery therapies remain insufficient. There are several new and vital antidiabetic agents under examination of many research clusters. Computational tools have influenced at levels. Hence, this study aimed to explain molecular interactions via an silico simulation approach between Aframomum melegueta seed-derived...
Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity data on the medicinal effects cannabis fertility. This study evaluated testicular function and quality modulation with in rats.Twenty-five Wistar rats were randomly grouped into five: A, B, C, D, each group have 5 rats. A (control): 0.2 ml 2% DMSO, B (vitamin C): 90 mg/kg body weight, E administered: mg/kg, 10 20 weight ethanolic leaf extract (ELEC) respectively. The...
To measure the transcript levels of Aurora kinases and compare them to their immunoreactivity patterns in prostate tumors.A total 26 cases cancer (PCa) 38 benign nodular hyperplasia (BPH) were sampled from archived formalin-fixed paraffin-embedded tissues. Tissue sections lysed, RNA extracted cDNA made by random hexamer priming while slide immunostained for kinases. Normalized relative quantitation was performed all using real-time PCR on TaqMan chemistry.The profile showed 15.4, 53.8 30.7%...
Staphylococcus aureus produces several toxins, including Panton-Valentine leukocidin (PVL). The involvement of PVL in primary skin infections, necrotizing pneumonia, musculoskeletal disorders, brain abscess, and other diseases, some which are life-threatening, has been reported. Following expert opinion, we aimed to provide the tools for establishment sequence-based diagnostics therapeutics those conditions. We engineered synergistic S F (LukS-PV LukF-PV respectively) pro-toxin subunits from...
Background and Objective: Wastage of more than 90% cashew apples fruits can significantly be curbed, thus, this study evaluated the potentials garlic-ginger filtrate as biopreservative compared with sodium benzoate ascorbic acid in unpasteurized apple juice.Materials Methods: Unpasteurized juices were pretreated 1% filtrate, (v/v) (v/v).About 100% juice served positive control.All samples stored on shelf at 26±2EC for 5 weeks.The pH, total titratable acidity, soluble solids, specific gravity...
The study aimed at reduction of wastage fruit, encourage production, consumption and preservation fruit juice blends using garlic ginger filtrate with health benefits as biopreservative thus providing alternatives biological advantage over chemical preservatives (ascorbic benzoate acids) without altering the organoleptic physicochemical properties blends. evaluated potential natural (ginger, ginger-garlic filtrates) in comparison two conventional for preservation. blend used was cashew,...
Currently, Nigeria is still at the ascending phase of COVID-19 curve with no sign deceleration. Thus, recent decision by governors states in northern to deport Almajirai (itinerant Islamic school pupils) from their as part efforts contain transmission likely have a serious backlash. With hundreds testing positive COVID-19, and millions others untested, they constitute ubiquitous nodes transmission. Their deportation has created multiple emigration channels that prospective feeders covert...
The major challenge influencing fruits economic value is the relatively short shelf-life. This study preserved fruit juice blend from pineapple, watermelon and orange using lime as biopreservative comparing its effectiveness with ascorbic acid citric chemical preservatives during storage at ambient temperature (27±2oC) for five weeks. acceptability of by consumer, biochemical changes microbial load was also evaluated on a weekly basis. From results, all samples were acceptable 9-point...
Hepatitis B infection is a public health concern globally. HBV can be associated with type II diabetes mellitus, as outbreaks have been observed among diabetics in healthcare facilities. This study evaluates the prevalence of patients mellitus.A total one hundred and eighty (180) diabetic one-hundred non-diabetics (Controls) were recruited for this study. Structured questionnaires administered to consented participants obtain relevant data. Sera samples obtained screened using HBsAg ELISA...
Staphylococcus aureus is a well-known agent of zoonotic infections. Livestock-associated methicillin-resistant S. (LA-MRSA) had been receiving public health attention for over decade. Recently, the genomes some MRSA strains evolved further by enabling acquisition vanA gene from enterococcus which drives emergence vancomycin-resistant (VRSA), thus signaling higher threat to antimicrobial chemotherapy and diagnostic microbiology. This study was designed examine slaughtered chicken carcasses in...
For longer than a century, the "meningitis belt" of sub-Saharan Africa has experienced largest-ever global meningitis epidemic. Whereas HIV-associated immunosuppression drives higher susceptibility to environmental infectious organisms with tropism for central nervous system (CNS), most diagnostic laboratories in belt stick N. meningitidis, H. influenzae, and S. pneumoniae. Cryptococcus neoformans been leading cause death (incidence, 89%; death, 75%). To establish whether services target...
Background: Malaria is one of the most common diseased conditions across developing countries caused by four species Plasmodium. P. falciparum and P.vivax are main agents responsible for malaria in Nigeria. Malarial infection has been shown to be associated with abnormalities fluids, electrolytes acid base balances. Electrolyte imbalance mineral disturbances majorly identified clinical symptoms various infectious diseases including malaria. malarial capable enhancing disease severity. The...