A5026603654- Cancer survivorship and care
- Childhood Cancer Survivors' Quality of Life
- Palliative Care and End-of-Life Issues
- Family Support in Illness
- Cancer-related cognitive impairment studies
- Circadian rhythm and melatonin
- Endometriosis Research and Treatment
- Medical Research and Treatments
- Nutrition and Health in Aging
- Endometrial and Cervical Cancer Treatments
- Neutropenia and Cancer Infections
- Sepsis Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- COVID-19 and healthcare impacts
- Colorectal Cancer Surgical Treatments
- Patient-Provider Communication in Healthcare
- Attachment and Relationship Dynamics
- Posttraumatic Stress Disorder Research
University of Delaware
2021-2025
Massachusetts General Hospital
2019-2021
Harvard University
2020
Moffitt Cancer Center
2017-2019
Caregivers of patients undergoing hematopoietic stem cell transplantation (HCT) experience an immense caregiving burden before, during, and after HCT.
Fear of cancer recurrence (FCR) is a common yet unaddressed concern among breast (BC) survivors and their intimate partners. Moderate-to-severe FCR has been associated with numerous negative health outcomes diminished functioning Therefore, it essential to understand what factors are higher for both patients Dispositional traits, such as optimism pessimism, have severity at the individual (intrapersonal) level. However, few studies focused on this link in dyadic, interpersonal context. To...
Chronic graft-versus-host disease (GVHD) is one of most common complications following allogeneic hematopoietic cell transplantation (HCT) and the significant contributor to morbidity nonrelapse mortality. The physical burdens psychosocial difficulties these patients have not been described systematically. An exploration into rates correlates mood quality life (QOL) in with chronic GVHD necessary develop a clinically relevant, evidence-based intervention promote well-being. From July 2015...
Background: The COVID-19 pandemic caused significant disruptions in cancer care, and preliminary research suggests that these are associated with increased levels of psychosocial distress among survivors. purpose this study was to offer a descriptive report the functioning, perceived risk fear progression, impact experiences unique, high-risk patient cohort: breast survivors whose treatment delayed and/or changed due pandemic. Methods: This cross-sectional included 50 women dual carcinoma...
Hematopoietic stem cell transplantation (HCT) is an intensive and potentially curative therapy for patients with hematologic malignancies. Patients admitted HCT experience a prolonged, isolating hospitalization endure substantial physical psychological symptoms. However, there paucity of research on the impact post-traumatic stress disorder (PTSD) symptoms in transplant recipients. This secondary analysis 250 who underwent autologous allogeneic examined PTSD using Checklist-Civilian measured...
Studies have shown gaps in prognostic understanding among patients with cancer. However, few studies explored patients' perceptions of their treatment goals versus how they perceive oncologist's goals, and the association these views psychological distress.We conducted a cross-sectional study 559 incurable lung, gastrointestinal, breast, brain cancers. The Prognosis Treatment Perception Questionnaire was used to assess reports goal goal, Hospital Anxiety Depression Scale symptoms.We found...
Pelvic exenteration (PE) in carefully selected gynecologic cancer patients has a 5-year survival rate as high 60%. Thus, there is growing number of PE survivors dealing with the effects this radical surgery. The current study sought to explore women's physical, psychological, and social quality life (QOL) after PE.Fourteen women who had undergone for recurrent at least 1 year previously completed semistructured qualitative interviews designed elicit expectations experiences QOL following PE....
Background Older adults with acute myeloid leukemia (AML) are often assumed to have poor outcomes after admission the intensive care unit (ICU). However, little is known about ICU utilization and post‐ICU in this population. Methods The authors conducted a retrospective analysis for 330 patients who were 60 years old or older diagnosed AML between 2005 2013 at 2 hospitals Boston.They used descriptive statistics examine proportion of admitted as well their mortality functional recovery. They...
Patients with head and neck cancer (HNC) report some of the highest levels psychological distress amid managing their disease as well debilitating disfiguring treatment side effects. Fear recurrence (FCR) is a top unmet need concern patients HNC. Prior research suggests elevated symptoms anxiety depression are potential antecedents to FCR, but findings have been limited in HNC populations. The aim present study was examine early level change relation later FCR among
Anhedonia, the loss of capacity to experience pleasure, is subjectively and biologically distinct from depressed mood. Few studies have specifically examined association pretransplantation anhedonia with key functional outcomes (eg, health-related quality life [QOL]) in patients hematologic malignancies who undergone hematopoietic stem cell transplantation (HSCT). Among 248 HSCT recipients enrolled 2 intervention trials, we associations between both QOL fatigue at weeks 6 months...
7505 Background: Patients admitted for HCT, an intensive and potentially curative therapy hematologic malignancies, experience a prolonged, isolating hospitalization endure substantial physical psychological symptom burden. However, data are limited regarding long-term post-traumatic stress (PTSD) in HCT survivors its risk factors. Methods: We conducted secondary analysis examining longitudinal from 250 patients who underwent autologous allogenic HCT. used the Post-Traumatic Stress Checklist...
Partners of breast cancer (BC) survivors report high rates psychological distress including fear recurrence (FCR). Research suggests that partners may have poorer physical health outcomes than the general population, but little research has examined physiological biomarkers by which impact partner outcomes. The current study associations between FCR and changes in hair cortisol among BC partners.
205 Background: Rates of illicit substance use and misuse opioid medications are high in the adolescent young adult (AYA) general population. Despite this, screening for is not standard care AYA oncology supportive/palliative care. To inform our clinical practice, we sought to determine prevalence potential cancer patients relative examine correlates misuse. Methods: We conducted retrospective chart review newly referred an outpatient palliative clinic between 2014 2016. Results: Consecutive...
Abstract Objective Although fear of cancer recurrence (FCR) has been conceptualized as a multidimensional construct with emotional and cognitive components, little work distinguished or assessed both components. Further, most existing research not included intimate partners patients, although they also experience FCR. This study aimed to (1) determine whether FCR is better singular at the within‐person level over time (2) model corresponding trajectories in patients their partners. Methods...
Background Caregivers (i.e., family and friends) of patients undergoing HCT experience immense caregiving burden during HCT. Multimodal interventions to address the needs caregivers prior to, during, after are lacking. Methods We conducted a randomized trial multimodal psychosocial intervention (BMT-CARE) for autologous allogeneic at Massachusetts General Hospital. were randomly assigned BMT-CARE or usual care. was tailored trajectory integrated treatment-related education self-care with...
11513 Background: Although hospice provides high-quality end-of-life (EOL) care for patients with advanced cancer and their family caregivers, the service remains underutilized in part due to lack of adequate information provided families about care. Methods: We conducted a single-site randomized clinical trial video decision aid versus verbal description 150 hospitalized caregivers. Patients without an available caregiver were still eligible participate. Intervention participants (75...
187 Background: Cancer anorexia-cachexia syndrome (CACS) in patients is associated with decreases lean body mass and weight. Self-reported lack of appetite may be an important indicator for early identification CACS. The current analyses examined the relationship perceived to patient characteristics overall symptom burden a large mixed cancer sample referred palliative care clinic. Methods: We conducted retrospective review newly outpatient clinic over two-year period. Data on demographic...
70 Background: Inpatient palliative care integrated with transplant has been shown to improve patient-reported quality of life (QOL), symptom burden, and psychological distress during hospitalization for HCT. However, the impact on supportive practices HSCT remains unknown. Methods: This secondary analysis is based a single-site randomized clinical trial 160 patients hematologic malignancies undergoing between 8/2014 1/2016. Participants received either inpatient (n = 81) or alone 79). We...
42 Background: Although hospice provides high-quality end-of-life care for patients with advanced cancer, the service remains underutilized in part due to lack of adequate information provided and families about care. Methods: We conducted a single-site randomized clinical trial video decision aid versus verbal description 150 hospitalized cancer their caregivers. Patients without an available caregiver were eligible participate. Intervention participants (75 patients; 18 caregivers)...