A5070407541- Oral microbiology and periodontitis research
- Cancer, Hypoxia, and Metabolism
- Connexins and lens biology
- Dental Health and Care Utilization
- Neonatal Respiratory Health Research
- Cleft Lip and Palate Research
- Circadian rhythm and melatonin
- Head and Neck Cancer Studies
- Free Radicals and Antioxidants
- Literature, Magical Realism, García Márquez
- Estrogen and related hormone effects
- ATP Synthase and ATPases Research
- Erythrocyte Function and Pathophysiology
- Oral Health Pathology and Treatment
- Periodontal Regeneration and Treatments
- RNA modifications and cancer
- Salivary Gland Disorders and Functions
Sun Yat-sen University
2019-2025
Hospital of Stomatology, Sun Yat-sen University
2019-2025
Stomatology Hospital
2019-2021
This study explored the role of Piezo1 in odontogenic differentiation dental papilla cells (DPCs) and tissue, focusing on a mechanism involving family with sequence similarity 83, member G (FAM83G). Here, we found Piezo1, mechanosensitive cation channel, was upregulated during odontogenesis DPCs tissues. Knockdown impaired differentiation, while its activation by Yoda1 enhanced process. Using 3D culture model an ectopic transplantation model, confirmed Piezo1’s vivo. RNA sequencing (RNA-seq)...
Dental caries among preschool children were prevalent worldwide and had a significant impact on their families. Understanding its prevalence risk factors helps to optimize the delivery of oral health care target population promote ultimately. This cross-sectional study aimed examine dental associated 3- 5-year-old in Huizhou, Guangdong Province, China.
Background Dental papilla cells (DPCs) are one of the key stem for tooth development, eventually forming dentin and pulp. Previous studies have reported that PER2 is expressed in a 24-hour oscillatory pattern DPCs vitro . In vivo , highly odontoblasts (which differentiated from DPCs). However, whether modulates odontogenic differentiation uncertain. This research was to identify function preliminarily explore its mechanisms. Methods We monitored expression used overexpression knockdown...
The construction of oral mucosa infection model in vitro is conducive to exploring the pathogenesis and prevention strategies infectious diseases mucosa. organotypic mucosal based on tissue-engineered mucosa, which cocultured with extraction pathogens, planktonic microorganisms, biofilm or saliva, mimic interactions between microbiome host. In recent years, researchers have used this technology study role microbes development periodontal diseases. This article reviews construction, advances...