Many university students are becoming involved in mentoring programs, yet few studies describe the impact of on mentor. Additionally, many report that graduating from college not prepared to enter workforce terms key career skills and/or content knowledge. Herein, we examine our program, NE STEM 4U (Nebraska Science, Technology, Engineering and Math for You), which undergraduate (UG) mentors engage K-8 youth after-school experiments. The UGs reflected upon their experiences using...

While the use of computer tools to simulate complex processes such as circuits is normal practice in fields like engineering, majority life sciences/biological sciences courses continue rely on traditional textbook and memorization approach. To address this issue, we explored Cell Collective platform a novel, interactive, evolving pedagogical tool foster student engagement, creativity, higher-level thinking. Web-based used create dynamical models various biological processes. Students can...

Afterschool interventions in STEM are linked to learning gains during the school day. These opportunities engage and excite students about concepts since they observe a more hands-on, project-oriented approach. Often these for afterschool infrequent nature leave gaps their maturation understanding. Herein we describe first report of an intervention, named NE 4U, targeting socioeconomically disadvantaged middle youth via twice weekly, year-long studied across two years. We assessed impact...

The Nebraska Science, Technology, Engineering, and Mathematics 4U (NE STEM 4U) program was initiated at the University of Omaha (UNO) in 2013. NE is a student-run, faculty-led facilitating problem-based learning (PBL) sessions science, technology, engineering, mathematics (STEM) for socioeconomically disadvantaged kindergarten through grade 8 (K-8) students. PBL are provided throughout academic year twice-weekly, after-school, informal education program. instructional material after school...

Caveolin-1 (CAV1) is a vital scaffold protein heterogeneously expressed in both healthy and malignant tissue. We focus on the role of CAV1 when overexpressed T- cell leukemia. Previously, we have shown that involved cell-to-cell communication, cellular proliferation, immune synapse formation; however, molecular mechanisms not been elucidated. hypothesize formation contributes to regulation during leukemic progression, thereby warranting studies CD4+ T cells relation antigen-presenting cells....

Despite surgery, chemotherapy, and radiotherapy treatments, the children, adolescents, young adults who are diagnosed with metastasized Ewing sarcoma face a dismal prognosis. Amyloid precursor-like protein 2 (APLP2) has recently been implicated in survival of cancer cells our current study, APLP2's contribution to was examined. APLP2 readily detected all cell lines analyzed by western blotting, TC71 expressing lowest level among lines. While irradiation induces apoptosis (as we determined...

In this qualitative study, we assessed the impact of NE STEM 4U intervention on elementary school youth in terms excitement, curiosity, and concepts. The incorporates a problem-based learning theoretical framework an after-school time, weekly or twice-weekly intervention. We student performance over two academic years participation using Dimensions Success observational tool. Ultimately, link mentor-led program with increases inquiry, concept gains. Taken together, these findings support...

This phenomenological study involves a unique, longitudinal assessment of the lived experiences former undergraduate mentors (n=7) in light their current (i.e., career or advanced schooling). The objective is to engage in-depth probing representative number participants. Specifically, we followed up with graduates Nebraska STEM 4U (NE 4U) intervention 3 years post-program, overall goal describing mentors’ using lens experiences. type perspective mentoring greatly lacking literature. At time...

Chronic Lymphocytic Leukemia (CLL), the most prevalent adult leukemia in western countries, which is highly heterogeneous with a very variable clinical outcome. Emerging evidence indicates that stromal tumor microenvironment (STME) and associated genes (SAG) play important roles pathogenesis progression of CLL. However, precise mechanisms by STME SAG are involved this process remain unknown. In an attempt to explore role process, we examined expression levels using gene profiling (GEP) CLL...

The development of critical thinking skills in recent college graduates is keenly requested by employers year after year. Moreover, improving these can help students to better question and analyze data. Consequently, we aimed implement a training program that would add the undergraduate students: Nebraska Science, Technology, Engineering, Math 4U (NE STEM 4U). In this program, undergraduates provide outreach, mentoring, science, technology, engineering, mathematics (STEM) education K-8...

Splenic marginal zone lymphoma (SMZL) is a rare, indolent non-Hodgkin's that affects 0.13 per 100,000 persons annually. Overall survival of SMZL estimated to reach 8 11 years in most cases, but up 30% cases develop aggressive presentations resulting greatly diminished time survival. presents with very heterogeneous molecular profile, making diagnosis problematic and accurate prognosis even less likely. The study herein has identified potential diagnostic gene expression signature highly...

The overall purpose of this multifocused study was to explore how participation in genuine mentored scientific research experiences impacts in-service science teachers and the knowledge skills needed for their own teaching. resulted from a partnership between University Nebraska at Omaha Public School District. This Teacher-Researcher Partnership Program facilitated opportunities inquiry, content, interaction with laboratory instrumentation technologies, critical discussion literature,...

Due to the SARS-CoV-2 pandemic (spring 2020), universities quickly moved remote instruction. Our research during this time frame included investigating course-based undergraduate experiences (CUREs) in General Chemistry, and we found ourselves middle of a CURE study without any laboratory component (aka "CURE-disrupted"). While literature surrounding importance CUREs is extensive, based on our search, posit that first report demonstrating student outcomes when given offering actually...

Neoplasms of extra-thymic T-cell origin represent a rare and difficult population characterized by poor clinical outcome, aggressive presentation, poorly defined molecular characteristics. Much work has been done to gain greater insights into distinguishing features among malignant subtypes, but there also exists need identify unifying characteristics assist in rapid diagnosis subsequent potential treatment. Herein, we investigated gene expression data five different mature lymphoma subtypes...

Mentoring is a common practice in higher education institutions and scientific fields. Undergraduates approach faculty members who are working on topics that match their research interests. We conducted study to compile qualitative synthesis of the mentorship experience undergraduate science students with mentors. used stages meta-ethnography guide our study. Meta-ethnography involves identifying concepts from studies translate them into line argument. screened 2,888 titles abstracts, 71...