Xianliang Yan

ORCID: 0000-0001-5102-2603
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About
Contact & Profiles
Research Areas
  • Cardiac Arrest and Resuscitation
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Sepsis Diagnosis and Treatment
  • Atrial Fibrillation Management and Outcomes
  • Heme Oxygenase-1 and Carbon Monoxide
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Anesthesia and Neurotoxicity Research
  • Coronary Interventions and Diagnostics
  • S100 Proteins and Annexins
  • Intensive Care Unit Cognitive Disorders
  • Mesenchymal stem cell research
  • Venous Thromboembolism Diagnosis and Management
  • Trauma and Emergency Care Studies
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Electron Spin Resonance Studies
  • 3D Printing in Biomedical Research
  • Immune Response and Inflammation
  • Bone Tissue Engineering Materials
  • Acute Myocardial Infarction Research
  • Heart Failure Treatment and Management
  • Transcranial Magnetic Stimulation Studies
  • Neurogenesis and neuroplasticity mechanisms
  • Cardiac, Anesthesia and Surgical Outcomes
  • Neurological Disease Mechanisms and Treatments
  • Tryptophan and brain disorders

Xuzhou Medical College
2016-2025

Xuzhou No.1 People's Hospital
2022-2025

Nanjing University of Chinese Medicine
2024

Beijing Anzhen Hospital
2014-2023

Capital Medical University
2014-2022

Jiangsu Provincial Center for Disease Control and Prevention
2022

Capital University
2021

Affiliated Hospital of Xuzhou Medical College
2008-2017

Shandong University
2013-2015

Novem (Netherlands)
2014

Rationale: The integrity and function of the blood-brain barrier (BBB) is compromised after stroke. current study was performed to examine potential beneficial effects underlying mechanisms repetitive transcranial magnetic stimulation (rTMS) on angiogenesis vascular protection, function, repair following stroke, which are largely unknown. Methods: Using a rat photothrombotic (PT) stroke model, continuous theta-burst rTMS administered once daily infarcted hemisphere for 5 min, beginning 3 h...

10.7150/thno.51573 article EN cc-by Theranostics 2020-01-01

In China many respiratory pathogens stayed low activities amid the COVID-19 pandemic due to strict measures and controls. We here aimed study epidemiological clinical characteristics of pediatric inpatients with Mycoplasma pneumoniae pneumonia (MPP) after mandatory restrictions were lifted, in comparison those before pandemic. included 4,296 patients MPP, hospitalized by two medical centers Jiangsu Province, China, from January 2015 March 2024. Patients divided into pre-COVID (n = 1,662)...

10.1186/s12879-024-10370-8 article EN cc-by-nc-nd BMC Infectious Diseases 2025-01-03

During cardiopulmonary resuscitation (CPR), the depth of compression is a critical factor affecting effectiveness rescue and patient's prognosis. However, it difficult to master correct in manual CPR. If too deep, may cause rib fractures, while insufficient fail establish effective circulation. Although most existing CPR control devices can indicate but lack direct limiting functions. Against this background, led by team faculty students from Department Emergency Rescue Medicine at Xuzhou...

10.3760/cma.j.cn121430-20240903-00743 article EN PubMed 2025-02-01

Continuous renal replacement therapy (CRRT) is widely used for treating critically-ill patients in the emergency department China. Anticoagulant needed to prevent clotting extracorporeal circulation during CRRT. Regional citrate anticoagulation (RCA) has been shown potentially be safer and more effective now recommended as preferred anticoagulant method However, there still a lack of unified standards RCA management world, are many problems using this clinical practice. The Emergency Medical...

10.1186/s40779-023-00457-9 article EN cc-by Military Medical Research 2023-05-29

Background Neutrophil/lymphocyte ratio (NLR) has been proposed as a novel marker of systemic inflammation and oxidative stress. The objective this study was to ascertain the relationship between levels NLR recurrence lone atrial fibrillation (AF) after catheter ablation. Methods A total 379 AF patients who underwent ablation were enrolled in study. before determined. Cox regression analyses used estimate AF. Results After mean follow-up (30.5±5.3) months, 124 (32.7%) had recurrences....

10.3760/cma.j.issn.0366-6999.20133001 article EN cc-by-nc-nd Chinese Medical Journal 2014-03-20

Delayed encephalopathy after acute carbon monoxide (CO) poisoning (DEACMP) is the most severe and clinically intractable complication that occurs following CO poisoning. Unfortunately, mechanism of DEACMP still vague. Growing evidence indicates delayed cerebral damage related to oxidative stress, abnormal neuro-inflammation, apoptosis immune-mediated injury. Our recent report indicated methylene blue (MB) may be a promising therapeutic agent in prevention neuronal cell death cognitive...

10.1111/bcpt.12940 article EN Basic & Clinical Pharmacology & Toxicology 2017-11-19

Abstract Repeated traumatic brain injury, leads to cumulative neuronal injury and neurological impairments. There are currently no effective treatments prevent these consequences. Growing interest is building in the use of transcranial photobiomodulation (PBM) therapy treat injury. Here, we examined PBM a repeated closed head (rCHI) rat model. Rats were administered total three injuries, with each separated by 5 days. treatment was initiated 2 hours after first daily for 15 We found that...

10.1002/jbio.201960117 article EN Journal of Biophotonics 2019-10-28

Macrophage infiltration is a hallmark pathological change observed in early stage myocardial ischemia/reperfusion (MI/R) injury and one of the main causes damage. Here, we investigated effects p-Coumaric acid (p-CA) on macrophage polarization following MI/R its mechanisms.

10.1080/21655979.2021.2001924 article EN Bioengineered 2021-11-05

Bone marrow mesenchymal stem cells (BMSCs) represent a promising tool for cell-based therapies. However, the majority of BMSC transplants only allow limited recovery lost functions. We previously found that human cerebrospinal fluid (hCSF) is more potent than growth factors in differentiating BMSCs into neuron-like vitro. In this study, we studied effect transplantation rat BMSC-derived (BMSC-Ns) induced by hCSF brain with middle cerebral artery occlusion (MCAO). The survival and...

10.3389/fneur.2016.00183 article EN cc-by Frontiers in Neurology 2016-10-27

Background: Most heart failure (HF) patients were complicated with atrial fibrillation (AF). Previous study has reported a correlation between soluble suppression of tumorigenicity 2 (sST2) and HF. While the association sST2 AF in HF remains elusive, which will strengthen our understanding patients. Methods: In study, case-control was conducted 306 enrolled from June 2019 to 2020 at Beijing Anzhen Hospital. All divided into following two groups, based on whether they complications prior...

10.21037/jtd-22-470 article EN Journal of Thoracic Disease 2022-05-01

The study aims to examine the predictive value of arterial blood lactic acid concentration for in-hospital all-cause mortality in intensive care unit (ICU) patients with acute heart failure (AHF). We retrospectively analyzed clinical data 7558 AHF Medical Information Mart Intensive Care IV (MIMIC-IV) database. exposure variable present was and outcome death. were divided into those who survived (n = 6792) died 766). multivariate logistic regression model, restricted cubic spline (RCS) plot,...

10.1155/2022/7644535 article EN cc-by International Journal of Clinical Practice 2022-11-16

Objectives To analyze the trends in mortality and causes of death among children under 5 years age Xuzhou, China between 2016 2020, order to protect children's health provide a basis for formulating child survival, development, protection strategies. Methods A population-based epidemiological study was conducted. Data were obtained from Xuzhou Center Disease Control Prevention. We input data into excel database analyzed with SPSS20.0. Results There 1,949 died The number deaths 2020 573...

10.3389/fped.2023.1067293 article EN cc-by Frontiers in Pediatrics 2023-02-21
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