A5049049612- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- Food Quality and Safety Studies
- Yersinia bacterium, plague, ectoparasites research
- Protein Hydrolysis and Bioactive Peptides
- Bacillus and Francisella bacterial research
- Ginseng Biological Effects and Applications
- Probiotics and Fermented Foods
- Nutrition, Health and Food Behavior
- Adipose Tissue and Metabolism
- Pneumocystis jirovecii pneumonia detection and treatment
- Insect Resistance and Genetics
- Peptidase Inhibition and Analysis
- Vector-borne infectious diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Respiratory viral infections research
- COVID-19 Clinical Research Studies
- Immune responses and vaccinations
- Microbial Metabolism and Applications
- Ethics and Legal Issues in Pediatric Healthcare
- Influenza Virus Research Studies
- Identification and Quantification in Food
- Biological and pharmacological studies of plants
Korea Disease Control and Prevention Agency
2019-2023
Korea University
2022
Korea Center for Disease Control and Prevention
2019
Sungkyunkwan University
2010-2013
Importance Vaccination against COVID-19 is an effective method for individuals to reduce negative health outcomes. However, widespread vaccination among children has been challenging owing parental hesitancy. Objective To examine decision-making in favor of the vaccine their and its association with sufficiency credibility information about vaccine. Design, Setting, Participants This cross-sectional survey study was conducted South Korea from February 7 10, 2022, weeks before initiation aged...
Abstract We used a nationwide population registry in South Korea to estimate the effect of second booster dose mRNA COVID-19 vaccine on risk for laboratory-confirmed SARS-CoV-2 infection, critical and death immunocompromised persons long-term care facility (LTCF) residents. During February 16–May 7, 2022, among 972,449 eligible persons, 736,439 (75.7%) received first 236,010 (24.3%) booster. Compared with group, at 30–53 days, recipients had effectiveness (VE) against all infections 22.28%...
We estimate the effectiveness of a fourth dose booster coronavirus disease 2019 mRNA vaccine in individuals aged ≥60 years during Omicron BA.2 and BA.5 circulation Korea. The against critical infection was 67.7% (95% confidence interval, 50.7%-78.8%) at 31-60 days 62.1% 45.5%-73.7%) 61-90 days.
We developed a biotin-streptavidin-based sandwich ELISA for the sensitive and specific detection of Yersinia pestis. In this assay, F1 capsular protein Y. pestis were captured by anti-F1 mouse monoclonal antibody followed with biotinylated-anti-F1 rabbit polyclonal HRP-conjugated streptavidin. The could detect not only up to 29 17 pg/ml but also 177.8 129.2 CFU/ml in PBS buffer human serum, respectively. addition, did show any cross-reactivity various proteins bacterial strains.
OBJECTIVES: Vaccination is one of the most important strategies to contain spread coronavirus disease 2019 (COVID-19). in children dependent on their parents, making it understand parents’ awareness and attitudes toward vaccines order devise raise vaccination rates children.METHODS: A web-based nationwide survey was conducted among Korean parents 7-year-old 18-year-old August 2021 estimate intention vaccinate against COVID-19 identify key factors affecting parental acceptance hesitancy...
동결건조된 김치분말을 주성분으로 하여 부형제로 glucose, 고춧가루, 식이섬유소 등을 혼합하여 제조된 김치 타블렛 제조용 조성물(KTC)의 항비만 효과를 알아보기 위하여 4주령의 SD계 수컷 흰쥐를 식이에 따라 정상대조군, 고지방식이군, 고지방 KTC 5%와 10% 첨가군의 4군으로 나누어 8주간 사육하고 체중, 피하지방, 혈당, 혈 중 지질농도, 간조직의 지질 농도와 HMG-CoA reductase 활성, 분변으로의 배설능 측정한 결과는 다음과 같다. 첨가량이 늘어날수록 흰쥐의 혈중 중성지질, 총콜레스테롤치를 농도 의존적으로 감소시켜 혈액내 지방의 축적을 저해하였고, 복부 피하지방의 양은 5%, 첨가군이 고지방군에 비해 13.6%, 21.3% 감소시켰다(p＜0.05). 또한 간과 심장, 고환의 중성지방, 콜레스테롤 농도는 고지방식이군에 감소하였고(p＜0.05), 활성 및 혈당 농도를 유의적으로 KTC가 비만을 억제함을 확인할 수 있었다.
This study was performed to investigate the effects of rice added with mulberry leaves and fruit on blood glucose, body fat serum lipid levels in Sprague-Dawley male rats for 4 weeks. Mulberry diet prepared mixture 50% purified AIN-diet formulated consisting soybean, barley, polished rice, black uncleaned bud, fruit. The experimental animals were fed (group A) B, diabetic control) weeks injected streptozotocin. In terms observing hypolipidemic effect either high-fat (13% fat) additional...
A pep27 mutant may be able to elicit mucosal immunity against pneumococcal diseases, and could employed as an inexpensive attenuated vaccine. However, this particular contains erythromycin-resistance marker. The purpose of the current study is develop a markerless assess whether inactivated induce immunity.Mice were vaccinated intranasally with every 2 weeks for total three times, after which time serum samples analyzed antibody titers. mice then challenged lethal D39 strain their survival...
Jun Ho Jeon, Ph.D., Chi-Hwan Choi, Jeong Hyun Kim, M.D., Junghee Hyun, M.S., Eun-Sun Sang-Yoon Yong-Woo Shin, Seong Wook Pyo, Dae-Won Byung Hak Kang, Young Joon Park, and Gi-eun Rhie, Ph.D.. Ann Lab Med 2021;41:489-92. https://doi.org/10.3343/alm.2021.41.5.489
We conducted a cohort study to assess vaccine effectiveness (VE) of coronavirus disease 2019 combinations on severe acute respiratory syndrome 2 critical infection and death among elderly population in Korea. From January August 2022, VE against for 4 doses mRNA recipients was 96.1%, whereas 1-dose viral vector + 3-dose had 90.8%.
본 연구는 천마분획물이 본태성고혈압쥐(SHR/NCrj)의 혈압과 혈청지질 농도에 미치는 영향을 평가하기 위하여 수행하였다. 실험은 1기와 2기로 나누어 수행하였는데, 실험1기는 3주 동안 흰쥐사료에 유지(lard : corn oil cholesterol=10 2 1%, w/w)를 첨가한 고지방식이를 급여하였고, 실험 2기는 5주 천마분획물로서 저분자분획(GR-1), 다당체분획(GR-2), 단백질분획(GR-3)을 경구투여하였다. 시험종료 체중은 고지방대조군(D)이 천마분획물군(A, B, C)보다 통계적으로 높았고, 식이섭취량은 D군이 천마분획물군보다 많았으며(p<0.05), 식이효율은 차이가 없었다. 중 총콜레스테롤(TC) 농도는 천마분획물군에서는 비슷하였고, 유의하게 높았다(p<0.05). 중성지방(TG) 천마분획물중 A군과 B군이 D군에 비해 각각 16, 19% 낮았다. 고밀도지단백-콜레스테롤(HDL) 다당체분획(B)이 비해서 21% 높았으며(p<0.05), 저밀도...
홍국고구마가 고지방식이를 섭취한 흰쥐의 배변량 및 지질대사 개선에 미치는 영향을 조사하고자 SD계 수컷 흰쥐를 대상으로 실험 1기(6주)에 급여하고, 2기(4주)에 3종의 고구마분말(일반, 홍국, 자색)을 5% 첨가한 식이를 급여했을 때, 배변량은 홍국고구마군(RYSP)이 고지방대조군(CON)에 비해 유의하게 증가하였고(p<0.05), 장 통과시간 역시 RYSP군이 가장 짧았다. 분변 중 총콜레스테롤(TC) 함량은 일반고구마군(WFSP)과 높았고(p<0.05), 그중에서도 더 높은 함량을 나타내었으며, 중성지방(TG) 농도는 WFSP군과 PFSP(자색고구마)군에 각각 9%, 26% 높았으나 유의성은 없었다. 반면 1일 총 지질배설량은 TC와 TG 모두 CON군과 PFSP군에 유의적으로 높았다(p<0.05). 혈청 TC CON군에 유의적 차이 없이 20% 감소하였고, LDL-C RYSP, PFSP군이 CON군보다 통계적으로 낮았으며(p<0.05), 실험군중 낮았고 이는 유의적인...
Probiotics colonize the intestines and exert an antibacterial effect on pathogens.Therefore, probiotics could be used as a preventive agent against lethal infections.To isolate probiotic microorganisms, 116 bacterial strains were isolated from healthy cow's milk subjected to Gram-stain, morphology biochemical analyses, Vitek analysis, 16S rRNA analysis.One of identified Bacillus (B.) thuringiensis 87 was found grow very well at pH 4.0~7.0 resistant high concentrations bile salts (0.3~0.9%...