A5101533675- Spectroscopy and Chemometric Analyses
- Traditional Chinese Medicine Analysis
- Catalytic Processes in Materials Science
- Spectroscopy Techniques in Biomedical and Chemical Research
- Catalysis and Oxidation Reactions
- Water Quality Monitoring and Analysis
- Analytical Chemistry and Chromatography
- Advanced Chemical Sensor Technologies
- Fault Detection and Control Systems
- Ginseng Biological Effects and Applications
- Chromatography in Natural Products
- Catalysts for Methane Reforming
- Atmospheric chemistry and aerosols
- Pharmacological Effects of Natural Compounds
- Rough Sets and Fuzzy Logic
- Gas Sensing Nanomaterials and Sensors
- Meat and Animal Product Quality
- Advancements in Battery Materials
- Advanced Image Fusion Techniques
- Saffron Plant Research Studies
- Antimicrobial Peptides and Activities
- Extraction and Separation Processes
- Zeolite Catalysis and Synthesis
- Optimal Experimental Design Methods
- Research studies in Vietnam
Beijing University of Chinese Medicine
2011-2024
State Administration of Traditional Chinese Medicine of the People's Republic of China
2011-2024
Institute of Coal Chemistry
2021-2023
University of Chinese Academy of Sciences
2021-2023
Beijing Hospital of Traditional Chinese Medicine
2019
Ministry of Education of the People's Republic of China
2016-2017
Beijing Municipal Education Commission
2016-2017
Beijing Normal University
2014
Peking University
2003-2010
CAE (Canada)
2006
The abuse of traditional antibiotics has caused a series health problems including antimicrobial resistance, which threatens human health. Therefore, searching for broad sources agents and developing multidimensional strategies to combat bacterial infections are urgent. Here, we reported two natural self-assembling modes between berberine (BBR) flavonoid glycosides: nanoparticles (NPs) nanofibers (NFs), were both mainly governed by electrostatic hydrophobic interactions. These nanostructures...
To transfer a calibration model in cases where the standardization samples are rare or unstable, method based on orthogonal space regression (OSR) is proposed. It uses virtual spectra to account for response changes between instruments batches. A comparative study of proposed OSR, piecewise direct standardization, finite impulse response, signal correction, and updating (MU) was conducted both pharmaceutical tablet data chlorogenic acid data. The results these studies suggest that OSR MU...
Merging traditional Chinese medicine's (TCM) principles of medicine-food homology with modern flavor chemistry, this research unveils PungentDB (http://www.pungentdb.org.cn/home), a database documenting 205 unique pungent compounds from 231 TCMs. It provides detailed insights into their chemical attributes, biological targets (including IC50/EC50 values), and molecular structures (2D/3D), enriched visualizations target organ distribution protein structures, exploring the space help...
Pharmacognosy Magazine,2015,11,41,8-13.DOI:10.4103/0973-1296.149674Published:January 2015Type:Original ArticleAuthors:Yang Li, Xinyuan Shi, Zhisheng Wu, Mingye Guo, Bing Xu, Xiaoning Pan, Qun Ma, and Yanjiang Qiao Author(s) affiliations:Yang Li1, Shi1, Wu1, Guo1, Xu1, Pan1, Ma2, Qiao1 1 Beijing University of Chinese Medicine; Key Laboratory TCM-information Engineering State Administration TCM, Beijing, China 2 for Basic Development Research on Medicine, Abstract:Background: Extraction...
The present work describes the systematic development of a robust, precise, and rapid reversed-phase liquid chromatography method for simultaneous analysis five chemical components in Panax notoginseng saponins (PNS) using quality by design (QbD). was developed two main phases: screening optimization. During phase, most suitable stationary column temperature, flow rate were identified, while secondary influential parameters, such as gradient slope, initial concentration acetonitrile,...
The fundamental principle of Quality by Design (QbD) is that the product quality should be designed into process through an upstream approach, rather than tested in downstream. keystone QbD modeling, and thus, to develop a control strategy based on development design space. Multivariate statistical analysis very useful tool support implementation pharmaceutical manufacturing. Nowadays, modeling mainly focused one-unit operations system for space across multi-unit still limited. In this...
The present work describes the validation of near infrared (NIR) method for quantification concentration <italic>licorice</italic> acid in blending process and talcum powder mixtures.
Panax Notoginseng Saponins (PNS), extracted from the roots of common TCM notoginseng (Burk.) F.H.Chen, consist notoginsenoside R 1 , ginsenoside Rg Re, Rb Rd and many other chemicals which haven’t been identified. Due to its popular pharmacological effects, it is importance control quality. This study combines design experiments space methodology optimize HPLC separation PNS. Three chromatographic parameters (i.e. temperature, initial proportion acetonitrile gradient slope) were selected...
The concept of real-time release testing (RTRT) has recently been adopted by the production pharmaceuticals in order to provide high-level guarantee product quality. Process analytical technology (PAT) is an attractive and efficient way for realizing RTRT. In this paper, near-infrared (NIR) determination cryptotanshinone tanshinoneII A content tanshinone extract powders was taken as research object. aim NIR analysis reliably declare compliant with its specification limits or not. First,...
To study the major metabolites of antitumor lead compound T-OA (oleanolic acyl-3, 5, 6-trimethyl pyrazine-2-methyl ester) in rat urine, order to preliminarily infer its metabolic mode rats.Rat urines blank group, raw material group (ligustrazine TMP and oleanolic acid OA Moore equivalent) were collected freeze-dried; Solids extracted by ethyl acetate; And then extracts re-dissolved with acetonitrile. HPLC-HRMS coupling technique was adopted find potential mass spectrum peak under ESI(+) (see...