Lu Wang

ORCID: 0000-0001-5108-9349
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About
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Research Areas
  • Ovarian function and disorders
  • Reproductive Biology and Fertility
  • Plasma Applications and Diagnostics
  • Assisted Reproductive Technology and Twin Pregnancy
  • Plasma Diagnostics and Applications
  • Combustion and Detonation Processes
  • Ovarian cancer diagnosis and treatment
  • Oral microbiology and periodontitis research
  • Gestational Diabetes Research and Management
  • Energetic Materials and Combustion
  • Biodiesel Production and Applications
  • Cancer, Hypoxia, and Metabolism
  • RNA modifications and cancer
  • Renal Diseases and Glomerulopathies
  • Coral and Marine Ecosystems Studies
  • Esophageal Cancer Research and Treatment
  • Marine Biology and Ecology Research
  • Streptococcal Infections and Treatments
  • Liver Disease Diagnosis and Treatment
  • Plasma and Flow Control in Aerodynamics
  • Ferroptosis and cancer prognosis
  • Hormonal and reproductive studies
  • Catalytic Processes in Materials Science
  • Reproductive Health and Technologies
  • Advanced Combustion Engine Technologies

Tianjin University of Science and Technology
2024

Shandong University
2014-2024

Beijing Jishuitan Hospital
2023

Peking University
2023

Zhengzhou Central Hospital
2021

Zhengzhou University
2014-2020

Henan University
2020

Obstetrics and Gynecology Hospital of Fudan University
2016-2020

Henan Provincial People's Hospital
2014-2020

Nanjing Medical University
2019

Whether non-alcoholic fatty liver disease (NAFLD) is a risk factor for gallstones remains uncertain. Few longitudinal or cohort studies have been used to identify this relationship. The aim of study was confirm the association between NAFLD and in urban dwellers China. To elucidate gallstones, we fitted generalized estimating equation (GEE) model large-scale over 6 years, which included 11,200 participants with at least three regular health check-ups. A total 498 cases occurred during 6-year...

10.1186/s12876-014-0213-y article EN cc-by BMC Gastroenterology 2014-12-01

Alzheimer's disease (AD) is heterogeneous and multifactorial neurological disorder; the risk factors of AD still remain elusive. Recent studies have highlighted role vascular in promoting progression suggested that ischemic events increase incidence AD. However, detailed mechanisms linking insult to largely undetermined. In this study, we established a transient cerebral ischemia model on young 5xFAD mice their non-transgenic (nonTg) littermates by occlusion bilateral common carotid...

10.1371/journal.pone.0144068 article EN cc-by PLoS ONE 2015-12-03

We explored the effects of different doses letrozole on incidence ovarian hyperstimulation syndrome (OHSS) after oocyte retrieval during in vitro fertilization (IVF) patients with high-risk OHSS. A total 88 were randomly divided into a control group, and groups treated 2.5 mg, 5 or 7.5 mg letrozole. found that from fifth day human chorionic gonadotrophin (hCG) treatment, E2 level decreased there statistical differences between four (p < 0.05). From eighth hCG luteinizing hormone (LH)...

10.3109/19396368.2014.957879 article EN Systems Biology in Reproductive Medicine 2014-09-05

To explore preconception risk factors for preeclampsia ( PE ) in women with polycystic ovary syndrome PCOS ), a prospective cohort study was conducted 92 infertile Chinese who had singleton pregnancy by ovulation induction and were followed up 6 weeks after delivery. The patients underwent assessment of physical, endocrine, metabolic features before induction. Fifteen (16.3%) diagnosed . Logistic regression analysis showed that sex hormone–binding globulin SHBG insulin level at 120 minutes,...

10.1111/jch.12957 article EN cc-by-nc-nd Journal of Clinical Hypertension 2016-12-27

Abstract Background Lactobacilli are often recognized as beneficial partners in human microbial environments. However, lactobacilli also cause diseases human, e.g. infective endocarditis (IE), septicaemia, rheumatic vascular disease, and dental caries. Therefore, the identification of potential pathogenic traits associated with will facilitate prevention treatment caused by lactobacilli. Herein, we investigated genomic a novel bacterial strain Lactobacillus paracasei LP10266 which has case...

10.1186/s12866-021-02253-8 article EN cc-by BMC Microbiology 2021-06-17

Abstract As a specific predictor of ovarian reserve, serum anti-Müllerian hormone (AMH) has become an area intense research interest in the field assisted reproductive technology. We assessed relationship between AMH levels and pregnancy outcomes Chinese patients investigate influencing factors cumulative live birth with high levels. A total 1379 starting their IVF/ICSI cycle were divided into normal (Group A, 1.1–4.0 ng/ml, n = 639) B, &gt; 4.0 740) groups by Live rate (LBR), (CLBR)...

10.1038/s41598-023-28724-8 article EN cc-by Scientific Reports 2023-02-06

This study aimed to explore valuable preconception predictors of gestational diabetes mellitus (GDM) in PCOS patients.A prospective cohort enrolling infertile Chinese women treated with ovulation induction was performed. The endocrine, metabolic and physical features all the patients were collected before pregnancy then followed up 6 weeks after delivery. prevalence GDM determined during 24-28 weeks. Logistic regression analysis receiver operating characteristic (ROC) curves applied risk...

10.1080/09513590.2017.1290074 article EN cc-by-nc-nd Gynecological Endocrinology 2017-02-28

Ovarian hyperstimulation syndrome (OHSS) is a potentially life-threatening, iatrogenic complication of ovarian stimulation in assisted reproduction technology. This complex characterised by enlarged ovaries with multiple corpora luteum, elevated sex steroid hormones serum and increased capillary permeability. Until now, the pathogenesis OHSS remains obscure, no absolute strategy can fully prevent without any side effect on ovulation clinical pregnancy. Using cultured human or mouse granulosa...

10.1093/molehr/gaz033 article EN Molecular Human Reproduction 2019-07-12

To explore the curative effect of Wenshentiaojing Decoction on treatment menstrual disorder caused by PCOS.Patients with disorders PCOS admitted to our department from January 2020 2021 were selected as research objects and divided into a control group observation according random number table method. The was treated Western medicine, basis medicine. clinical efficacy two groups compared. Before after treatment, sex hormones (LH, FSH, LH/FSH, testosterone (T)), ovarian volume, endometrial...

10.1155/2021/4975867 article EN Evidence-based Complementary and Alternative Medicine 2021-11-29

Colon adenocarcinoma (COAD) is a prevalent gastrointestinal malignant disease with high mortality rate, and identification of novel prognostic biomarkers therapeutic targets urgently needed. Although neurexophilin 4 (NXPH4) has been investigated in several tumors, its role COAD remains unclear. The aim this study was to explore the value potential functions NXPH4 COAD.

10.21037/jgo-23-956 article EN Journal of Gastrointestinal Oncology 2024-04-01

Abstract Previous findings have highlighted the association between oxidized high‐density lipoprotein (ox‐HDL) and polycystic ovary syndrome (PCOS) development; however, underlying mechanism remains unclear. Under such context, present study aimed to investigate involvement of ox‐HDL in PCOS relation p65/micro‐RNA‐34a (miR‐34a)/FOS axis. rat models were established with injection dehydroepiandrosterone (6 mg/100 g body weight). Both PCOS‐modelled rats granulosa cells (GCs) received treatment...

10.1111/jcmm.16197 article EN Journal of Cellular and Molecular Medicine 2021-08-04

Objective: Mifepristone, as a type of well-accepted emergency contraceptive drugs, is an optional progesterone receptor modulator and widely used clinically. However, the effect mifepristone on sperms poorly studied. This research intended to investigate biological human sperm function in vitro. Methods: Spermatozoa were incubated culture medium containing 0.04 μM, 0.4 4 μM 40 for one hour after capacitation. It was required measure motility, viability, DNA integrity, acrosomal reaction,...

10.14725/dcc.v5n3p18 article EN Discussion of Clinical Cases 2018-09-10

Objective To investigate the clinical outcomes of in vitro fertilization-embryo transfer (IVF-ET) between donor and recipient. Methods Pregnancy 31 donors infertility patients ovarian hyperresponsiveness 30 recipients receiving by IVF-ET from January 2011 to December 2016 Reproductive Center Henan Provincial People's Hospital were retrospectively analyzed. Results The implantation rate frozen-thawed embryo (FET) cycle (52.05% vs. 58.70%), pregnancy (69.23% 73.91%), live birth...

10.3760/cma.j.cn101441-20190807-00349 article EN Chin J Reprod Contracep 2020-04-25

Objective To evaluate the changes of mTOR signaling molecules in granulosa cells from polycystic ovary syndrome (PCOS) patients, and whether change siganaling is related to serum hormones. Methods The phosphorylation levels primary were compared between PCOS group control group. The correlation hormones was also analyzed. Then effects exogenous testosterone insulin on investigated vitro. Results Granulosa patients (0.66±0.29) had higher with (0.34±0.32, P=0.02). level p-s6k1...

10.3760/cma.j.cn101441-20190326-00122 article EN Chin J Reprod Contracep 2020-04-25
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