A5101711941- Particle accelerators and beam dynamics
- Nuclear Physics and Applications
- Superconducting Materials and Applications
- Nuclear physics research studies
- Particle Accelerators and Free-Electron Lasers
- Advanced NMR Techniques and Applications
- Magnetic confinement fusion research
- Muon and positron interactions and applications
- Physics of Superconductivity and Magnetism
- Gyrotron and Vacuum Electronics Research
- Solid-state spectroscopy and crystallography
- Radiation Detection and Scintillator Technologies
- Radiopharmaceutical Chemistry and Applications
- Atomic and Molecular Physics
- Nuclear reactor physics and engineering
- Radiation Therapy and Dosimetry
- Ion-surface interactions and analysis
- Atomic and Subatomic Physics Research
- Astronomical and nuclear sciences
- Semiconductor materials and devices
- Particle Detector Development and Performance
- Radiation Effects in Electronics
- Medical Imaging Techniques and Applications
- Plasma Diagnostics and Applications
- Luminescence Properties of Advanced Materials
Osaka University
2016-2025
Nagoya Institute of Technology
2024
Okayama University
2024
The University of Tokyo
2021
Core Laboratories (United States)
2019
Kyoto University Research Reactor Institute
2013
University College London
2013
High Energy Accelerator Research Organization
2013
IMEC
2011
Fujitsu (China)
2011
Abstract Optical recording with a voltage‐sensitive dye was performed in visual cortical slices of the rat to determine effect acetylcholine (ACh) on spread excitation. In presence ACh, excitation initiated by stimulation at white matter/layer VI (WM/VI) greatly suppressed throughout cortex, less suppression middle layers. By comparing ACh that 6‐cyano‐7‐nitroquinoxaline‐2,3‐dione (CNQX), fraction synaptic component sensitive evaluated. ∼ 40–50% (maximum 55.8%, n = 11) initial superficial...
Precise measurements of the reaction cross sections ($\ensuremath{\sigma}{}_{\mathrm{R}}$) for $^{12}\mathrm{C}$ on Be, C, and Al targets $^{11}\mathrm{Be}$ Be were performed in energy range between 30 400 MeV/nucleon. The dependencies $\ensuremath{\sigma}{}_{\mathrm{R}}$ $^{12}\mathrm{C}$, $^{11}\mathrm{Be}$, $^{8}\mathrm{B}$ compared to Glauber-type calculations using reliable nucleon-density distributions that are supported by experimental data. It was found calculations, which include...
<sup>211</sup>At is an α-emitter that has similar chemical properties to iodine and used in targeted α-therapy. In the present study, we added ascorbic acid (AA) solution increase radiochemical purity of astatide evaluated its efficacy against differentiated thyroid cancer, which characterized by expression sodium/iodide symporter (NIS). <b>Methods:</b> Crude (AA(−)) treated with AA (AA(+)) were prepared. Uptake was compared between 2 solutions normal male Wistar rats (<i>n</i> = 6)....
Interaction cross sections for ^{42-51}Ca on a carbon target at 280 MeV/nucleon have been measured the first time. The neutron number dependence of derived root-mean-square matter radii shows significant increase beyond magic N=28. Furthermore, this enhancement is much larger than that previously charge radii, indicating novel growth in skin thickness. A simple examination based Fermi-type distribution, and mean field calculations point out anomalous nuclear size N=28 results from an...
Abstract α‐Methyl‐ l ‐tyrosine (AMT) has a high affinity for the cancer‐specific ‐type amino acid transporter 1 (LAT1). Therefore, we established an anti‐cancer therapy, with 211 At‐labeled α‐methyl‐ ( At‐AAMT) as carrier of At into tumors. At‐AAMT had LAT1, inhibited tumor cell growth, and induced DNA double‐stranded breaks in vitro . We evaluated accumulation vivo role LAT1. Treatment 0.4 MBq/mouse growth PANC‐1 model metastasis lung B16F10 model. Our results suggested that would be useful...
In coils wound with high-temperature superconducting (HTS) tapes, large screening currents are induced in the tape by radial component of magnetic field. Furthermore, when a transport current is supplied to HTS under field, total (which consists and currents) flows inhomogeneously. The field generated affects distribution cyclotron applications. Investigating effects on reduction, hysteresis, drift coil therefore necessary. our previous studies, we have developed novel simulation code for...
In recent years, the quality of high-temperature superconducting (HTS) tapes has been improving rapidly, becoming available in sufficient quantity and length, can be applied to devices for power systems industrial applications. Therefore, we are carrying out a feasibility study on application HTS coil medical accelerator system particle cancer therapy, designing new cyclotron that is compact, highly efficient, able extract high-energy beam consume less power. this paper, report our effort...
A new muon beamline, science innovative channel (MuSIC), was set up at the Research Centre for Nuclear Physics (RCNP), Osaka University, in Osaka, Japan, using 392 MeV proton beam impinging on a target. The production of an intense relies efficient capture pions, which subsequently decay to muons, novel superconducting solenoid magnet system. After pion-capture first $36^\circ$ curved transport line commissioned and flux measured. In order detect target either copper or magnesium placed stop...
The existence of nicotinic acetylcholine receptors (nAChR) on lymphocytes remains controversial. We attempted to show the nAChR murine lymphocytes. intraperitoneal injection nicotine induced lymphocytosis in spleen day 3. Although freshly isolated bound small quantities fluorescein isothiocyanate (FITC)‐conjugated &agr;‐bungarotoxin (&agr;BuTx), they began bind &agr;BuTx after incubation medium. In contrast granulocytes, various lymphocyte subsets obtained from lymphoid organs...
We have developed a robust latch for achieving high reliability in LSI. The can attenuate multi-node single-event-upset (MNSEU) and single event transient on local-clock (SETLC). has Dual-clock-buffers (DCB) Double-height-cell (DHC) technologies. Results neutron acceleration experiments show that DHC dramatically MNSEU DCB protect almost SETLC of the latch. In addition, we investigate optimum design well structure.
We intend to develop and obtain a compact, high-efficiency high-performance cyclotron using the high-temperature superconducting (HTS) magnet technology. In applications, high-accuracy magnetic field distribution with an isochronous azimuthally varying is spatially temporally required for HTS coil. coils wound tapes, large shielding currents are induced in tape by radial component of field. The generated current affects application following issues: (1) reduction current, (2) accuracy...
The nuclear shell structure, which originates in the nearly independent motion of nucleons an average potential, provides important guide for our understanding structure and underlying forces. Its most remarkable fingerprint is existence so-called `magic numbers' protons neutrons associated with extra stability. Although introduction a phenomenological spin-orbit (SO) coupling force 1949 helped explain magic numbers, its origins are still open questions. Here, we present experimental...
We have measured for the first time charge-changing cross sections ($\sigma_{\text{CC}}$) of $^{12-16}$C on a $^{12}$C target at energies below $100A$ MeV. To analyze these low-energy data, we developed finite-range Glauber model with global parameter set within optical-limit approximation which is applicable to reaction section ($\sigma_{\text{R}}$) and $\sigma_{\text{CC}}$ measurements incident from 10$A$ $2100A$ Adopting proton-density distribution known electron-scattering as well bare...
The 30-deg white neutron beam at the Research Center for Nuclear Physics (RCNP) cyclotron facility has been characterized as a probe suitable testing of single-event effects (SEE) in semiconductor devices energy range from 1 to 300 MeV using 392-MeV proton incident reaction on 6.5-cm-thick tungsten target. spectrum obtained by time-of-flight measurements reproduced terrestrial flux distribution sea level, and intensity increased factor 1.5 × 108 became available. average region 10 100 RCNP...
In autumn 2017, the project "Quantum Innovation for Safe and Smart Society (QiSS)" was started in Program on Open Platform with Enterprises, Research Institute Academia (OPERA) by Japan Science Technology Agency (JST). One of key issues this is advancement compact cyclotron beam irradiation device stable supply short-lived radioisotope (RI). We proposed air-core using high-temperature superconducting (HTS) technology, named Skeleton Cyclotron, as high intensity cyclotron. Currently, we are...
It has been known that uniformization of a beam with Gaussian profile is possible utilizing odd-order nonlinear focusing in the transport system, and this recently employed for uniform irradiation. Here, we have theoretically studied transverse using nonlinear-focusing forces produced by multipole magnets detail. In case where field magnet given an infinite power series, all strengths required extent resultant region expressed Twiss parameters. We shown principle even-order fields. also...
We have precisely measured reaction cross sections (σR) for 8Li using 9Be, 12C, 27Al, and proton targets at intermediate energies by the transmission method. From energy dependence of σR including high data, density distribution was deduced through a modified Glauber model. It is shown that has shorter tail structure in as compared with 8B matter radius similar to those other nonhalo Li isotopes. The result consistent previous experiments there tendency be skin nucleus.Received 7 July...
Charge-changing cross sections $\sigma_\mathrm{CC}$ for $^{42\textrm{--}51}$Ca on a carbon target at around 280~MeV/nucleon have been measured. The measured values differ significantly from the previously developed calculations based Glauber model. However, through introduction of charged-particle evaporation effect induced by neutron-removal reaction in addition to Glauber-model calculation, experimental $^{12}$C 300~MeV/nucleon nuclides C Fe isotopes are all reproduced with approximately...
One- and two-neutron removal reactions from 19C 20C have been studied using a liquid-hydrogen target at 40A MeV. A small cross section has observed in the one-neutron reaction 20C. The inclusive sections are compared with theoretical calculated by shell model spectroscopic factors Glauber-model single-particle sections. momentum distributions also those continuum-discretized coupled-channel methods. Good consistency between theory experiment is shown 19C. However, our calculation fails to...