A5003803060- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Genetics and Plant Breeding
- Cancer-related molecular mechanisms research
- Genetic diversity and population structure
- Reproductive Physiology in Livestock
- Animal Genetics and Reproduction
- Chromosomal and Genetic Variations
- Livestock and Poultry Management
- Meat and Animal Product Quality
- Reproductive Biology and Fertility
- Genomics and Phylogenetic Studies
- Prenatal Screening and Diagnostics
- Carbohydrate Chemistry and Synthesis
- Glycosylation and Glycoproteins Research
Digital Research Alliance of Canada
2019-2021
L'Alliance Boviteq
2021
University of Guelph
2019-2020
Parco Tecnologico Padano
2014-2018
University of Sassari
2013-2015
Increased inbreeding is an inevitable consequence of selection in livestock populations. The analysis high-density single nucleotide polymorphisms (SNPs) facilitates the identification long and uninterrupted runs homozygosity (ROH) that can be used to identify chromosomal regions are identical by descent. In this work, distribution ROH different lengths five Italian cattle breeds described. A total 4095 bulls from (2093 Holstein, 749 Brown, 364 Piedmontese, 410 Marchigiana 479 Simmental)...
Abstract Background The development of high-throughput sequencing and genotyping methodologies has enabled the identification thousands genomic regions associated with several complex traits. integration multiple sources biological information is a crucial step required to better understand patterns regulating these Findings Genomic Annotation in Livestock for positional candidate LOci (GALLO) an R package developed accurate annotation genes quantitative trait loci (QTLs) located identified...
Since goat was domesticated 10,000 years ago, many factors have contributed to the differentiation of breeds and these are classified mainly into two types: (i) adaptation different breeding systems and/or purposes (ii) environments. As a result, approximately 600 developed worldwide; they differ considerably from one another in terms phenotypic characteristics adapted wide range climatic conditions. In this work, we analyzed AdaptMap dataset, which is composed data more than 3000 animals...
Patterns of homozygosity can be influenced by several factors, such as demography, recombination, and selection. Using the goat SNP50 BeadChip, we genotyped 3171 goats belonging to 117 populations with a worldwide distribution. Our objectives were characterize number length runs (ROH) detect ROH hotspots in order gain new insights into consequences neutral selection processes on genome-wide patterns goats. The proportion genome covered is, general, less than 15% an inverse relationship...
Genetic isolation of breeds may result in a significant loss diversity and have consequences on health performance. In this study, we examined the effect geographic caprine genetic patterns by genotyping 480 individuals from 25 European African with Goat SNP50 BeadChip comparing homozygosity insular nearby continental breeds.Among analysed, number total length ROH varied considerably depending breeds, could cover substantial fraction genome (up to 1.6 Gb Icelandic goats). When compared their...
Summary Selection is the major force affecting local levels of genetic variation in species. The availability dense marker maps offers new opportunities for a detailed understanding diversity distribution across animal genome. Over last 50 years, cattle breeds have been subjected to intense artificial selection. Consequently, regions controlling traits economic importance are expected exhibit selection signatures. fixation index ( F st ) an estimate population differentiation, based on...
Domestication and selection are processes that alter the pattern of within- between-population genetic variability. They can be investigated at genomic level by tracing so-called signatures. Recently, sequence polymorphisms genome-wide have been in a wide range animals. A common approach to detect signatures is compare breeds selected for different breeding goals (i.e. dairy beef cattle). However, variations with similar production aptitudes phenotypes related differences their history. In...
Approximately one million in vitro produced (IVP) cattle embryos are transferred worldwide each year as a way to improve the rates of genetic gain. The most advanced programmes also apply genomic selection at embryonic stage by SNP genotyping and calculation estimated breeding values (GEBVs). However, high proportion fail establish pregnancy. Here, we demonstrate that further interrogation data collected for GEBVs can effectively remove aneuploid from pool, improving live births per embryo...
Cattle include a large number of breeds that are characterized by marked phenotypic differences and thus constitute valuable model to study genome evolution in response processes such as selection domestication. Detection "signatures selection" is useful approach the evolutionary pressures experienced throughout history. In present study, signatures were investigated five cattle farmed Italy using multivariate approach.A total 4094 bulls from with different production aptitudes (two dairy...
Abstract Background The advent of genomic information and the reduction in cost genotyping have led to use estimate inbreeding as an alternative pedigree inbreeding. Using measures, effects on production fertility traits been observed. However, there limited studies specific regions causing observed negative association with trait interest. Our aim was identify unique run homozygosity (ROH) genotypes present within a given window that display associations quantify these identified ROH...
The detrimental effects of increased homozygosity due to inbreeding have prompted the development methods reduce inbreeding. detection runs (ROH), or contiguous stretches homozygous marker genotypes, can be used describe and quantify level in an individual. estimation coefficients calculated based on pedigree information, ROH, genomic relationship matrix. aim this study was detect ROH turkey genome compare estimates pedigree-based (FPED) with genomic-based estimated from (FROH) matrix...
The objective of the present study was to test ability partial least squares regression technique impute genotypes from low density single nucleotide polymorphisms (SNP) panels i.e. 3K or 7K a high panel with 50K SNP. No pedigree information used. Data consisted 2093 Holstein, 749 Brown Swiss and 479 Simmental bulls genotyped Illumina Beadchip. First, single-breed approach applied by using only data Holstein animals. Then, enlarge training population, three breeds were combined multi-breed...
One of the main advantages single nucleotide polymorphism (SNP) array technology is providing genotype calls for a specific number SNP markers at relatively low cost. Since its first application in animal genetics, available arrays each species has been constantly increasing. However, conversely to that observed whole genome sequence data analysis, does not have common set file formats or coding conventions allele calling. Therefore, standardization and integration from multiple sources...