Catherine R. Nelson
A5086911032- Genomics and Phylogenetic Studies
- Genetic Mapping and Diversity in Plants and Animals
- Plant Pathogenic Bacteria Studies
- Chromosomal and Genetic Variations
- RNA and protein synthesis mechanisms
- Genomics and Chromatin Dynamics
- CRISPR and Genetic Engineering
- GABA and Rice Research
- Plant-Microbe Interactions and Immunity
- Plant Reproductive Biology
- DNA Repair Mechanisms
- Plant Genetic and Mutation Studies
- Insect Resistance and Genetics
- Plant Virus Research Studies
- RNA Research and Splicing
- Selenium in Biological Systems
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Primary Care and Health Outcomes
- Rice Cultivation and Yield Improvement
- Plant Disease Resistance and Genetics
University of California, Davis
1998-2019
ORCID
2019
Translational Genomics Research Institute
2019
Joint Genome Institute
2019
University of California System
2019
Wuhan Academy of Agricultural Sciences
2019
State Key Laboratory of Agricultural Microbiology
2019
HudsonAlpha Institute for Biotechnology
2019
Czech Academy of Sciences, Institute of Biotechnology
2019
Guy's and St Thomas' NHS Foundation Trust
2011
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion human genome was generated by whole-genome shotgun sequencing method. The 14.8-billion bp DNA over 9 months from 27,271,853 high-quality reads (5.11-fold coverage genome) both ends plasmid clones made five individuals. Two assembly strategies—a and a regional chromosome assembly—were used, each combining data Celera publicly funded effort. public were shredded into 550-bp segments to create 2.9-fold those regions...
The fly Drosophila melanogaster is one of the most intensively studied organisms in biology and serves as a model system for investigation many developmental cellular processes common to higher eukaryotes, including humans. We have determined nucleotide sequence nearly all ∼120-megabase euchromatic portion genome using whole-genome shotgun sequencing strategy supported by extensive clone-based high-quality bacterial artificial chromosome physical map. Efforts are under way close remaining...
A comparative analysis of the genomes Drosophila melanogaster , Caenorhabditis elegans and Saccharomyces cerevisiae —and proteins they are predicted to encode—was undertaken in context cellular, developmental, evolutionary processes. The nonredundant protein sets flies worms similar size only twice that yeast, but different gene families expanded each genome, multidomain signaling pathways fly worm far more complex than those yeast. has orthologs 177 289 human disease genes examined provides...
The Drosophila melanogaster genome was the first metazoan to have been sequenced by whole-genome shotgun (WGS) method. Two issues relating this achievement were widely debated in genomics community: how correct is sequence with respect base-pair (bp) accuracy and frequency of assembly errors? And, difficult it bring a WGS accepted standard for finished sequence? We are now position answer these questions.Our finishing process designed close gaps, improve quality validate assembly. Sequence...
We constructed a bacterial artificial chromosome (BAC)–based physical map of chromosomes 2 and 3 Drosophila melanogaster , which constitute 81% the genome. Sequence tagged site (STS) content, restriction fingerprinting, polytene in situ hybridization approaches were integrated to produce spanning euchromatin. Three five remaining gaps are repeat-rich regions near centromeres. A tiling path clones this STS maps X 4 was sequenced low coverage; sequence used support verify whole-genome...
The availability of thousands complete rice genome sequences from diverse varieties and accessions has laid the foundation for in-depth exploration genome. One drawback to these collections is that most have long life cycles, and/or low transformation efficiencies, which limits their usefulness as model organisms functional genomics studies. In contrast, variety Kitaake a rapid cycle (9 weeks seed seed) easy transform propagate. For reasons, emerged studies monocotyledonous species.Here, we...
Abstract The claret (ca) locus of Drosophila melanogaster comprises two separately mutable domains, one responsible for eye color and proper disjunction chromosomes in meiosis early cleavage divisions. Previously isolated alleles are three types: (1) the type that affect only, (2) claret-nondisjunctional (cand) chromosome behavior, (3) a meiotic mutation, non-claret disjunctional (ncd), affects behavior only. In order to investigate genetic structure locus, we have 19 radiation-induced on...
Abstract We studied the timing of mitotic loss maternally and paternally derived chromosomes among progeny Drosophila melanogaster females homozygous for an amorphic mutation in ncd , a gene encoding kinesin‐like protein. In order to determine division at which chromosome occurs, we estimated fraction XO nuclei resulting from X by scoring phenotype 47 adult cuticular landmarks 160 XX – mosaics (gynandromorphs) maternal loss, 33 gynandromorphs paternal loss. The results show that while most...
Abstract Background: The availability of thousands complete rice genome sequences from diverse varieties and accessions has laid the foundation for in-depth exploration genome. One drawback to these collections is that most have long life cycles, and/or low transformation efficiencies, which limits their usefulness as model organisms functional genomics studies. In contrast, variety Kitaake a rapid cycle (9 weeks seed seed) easy propagate. For reasons, emerged studies monocotyledonous...
Abstract Background: The availability of thousands complete rice genome sequences from diverse varieties and accessions has laid the foundation for in-depth exploration genome. One drawback to these collections is that most have long life cycles, and/or low transformation efficiencies, which limits their usefulness as model organisms functional genomics studies. In contrast, variety Kitaake a rapid cycle (9 weeks seed seed) easy propagate. For reasons, emerged studies monocotyledonous...
Abstract Background: The availability of thousands complete rice genome sequences from diverse varieties and accessions has laid the foundation for in-depth exploration genome. One drawback to these collections is that most have long life cycles, and/or low transformation efficiencies, which limits their usefulness as model organisms functional genomics studies. In contrast, variety Kitaake a rapid cycle (9 weeks seed seed) easy propagate. For reasons, emerged studies monocotyledonous...
Abstract Here, we report the de novo genome sequencing and analysis of Oryza sativa ssp. japonica variety KitaakeX, a Kitaake plant carrying rice XA21 immune receptor. Our KitaakeX sequence assembly contains 377.6 Mb, consisting 33 scaffolds (476 contigs) with contig N50 1.4 Mb. Complementing are detailed gene annotations 35,594 protein coding genes. We identified 331,335 genomic variations between Nipponbare (ssp. ), 2,785,991 Zhenshan97 indica ). also compared resequencing reads to 219...