A5019374861- Gestational Diabetes Research and Management
- Sperm and Testicular Function
- Ovarian function and disorders
- Pregnancy and preeclampsia studies
- Mesenchymal stem cell research
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Biology and Fertility
- Immunodeficiency and Autoimmune Disorders
- Cardiac and Coronary Surgery Techniques
- Vitamin D Research Studies
- Tissue Engineering and Regenerative Medicine
- Diabetes and associated disorders
- Cardiac Ischemia and Reperfusion
- Birth, Development, and Health
- Pediatric health and respiratory diseases
- COVID-19 Clinical Research Studies
- Law, AI, and Intellectual Property
- Reproductive Health and Contraception
- Regulation of Appetite and Obesity
- Chronic Disease Management Strategies
- Blood groups and transfusion
- Blood disorders and treatments
- Primary Care and Health Outcomes
- Toxoplasma gondii Research Studies
- Hormonal and reproductive studies
Royan Institute
2008-2024
Academic Center for Education, Culture and Research
2012-2024
Iran University of Medical Sciences
2018-2022
Children's Medical Center
2004
University of Tehran
2004
Tehran University of Medical Sciences
2004
Summary Although vitamin D deficiency is one of the most common health problems throughout world, including Iran, conflicting information exists on potential association between serum levels and semen quality. This study intended to evaluate [25( OH ) D3] with quality hormones in Iranian subfertile men. We also compared mean hormone normospermic men oligoasthenoteratozoospermia ( OAT cross‐sectional was conducted 278 who were referred Royan Infertility Clinic (Tehran, Iran) from March...
Background: Gestational diabetes mellitus (GDM) is a major pregnancy endocrine problem that has several confirmed risk factors and associated with adverse pregnancy-related outcomes (PRO). Objective: To evaluate the relationship between GDM diagnosis of PRO (maternal, intrapartum, perinatal, neonatal) in accordance International Association Diabetes Pregnancy Study Groups criteria. Materials Methods: This prospective cohort study was performed 531 singleton parturient (265 266 non-GDM). They...
The CD133(+) bone marrow cell (BMC) population includes primitive multipotent stem cells which induce neoangiogenesis. Studies suggested transplantation of these to infarcted myocardium can have a favorable impact on tissue perfusion and contractile performance. We assessed the feasibility, safety functional outcomes autologus BMC during coronary artery bypass grafting (CABG) in patients with recent myocardial infarction. In prospective, nonrandomized, open-label study, 27 infarction...
Growing evidence indicates that the risk of obstetric and perinatal outcomes is higher in women with assisted reproductive technology (ART). However, there little known about pregnancy related complications co-morbidity gestational diabetes mellitus (GDM) following singleton pregnancies achieved by ART comparison spontaneous conception (SC).Two hundred sixty pregnant conceived 314 (SC) were participated this prospective cohort study. All participants enrolled after GDM screening through...
Tilting the balance in favor of antioxidant agents could increase infertility problems obese and diabetic individuals. The aim this study was to evaluate oxidative stress status semen men with type 2 diabetes obesity investigate whether excessive amounts stress, as a result obesity, influence potential.A case-control conducted (n=150) attending Infertility Center Royan Institute between December 2016 February 2017. Participants were categorized into four groups; normal weight (BMI<25 kg/m2)...
Abstract Background Subfertility in obese and diabetic men during the reproductive age is evident, but mechanisms by which obesity diabetes mellitus cause male infertility are not entirely understood . The current study aimed to evaluate effects potential of on fertility. Methods We enrolled control = 40, Lean-DM 35, Obese-DM 35 individuals. obesity-associated markers, hormonal lipid profile, inflammatory indices, semen analysis were assessed four experimental groups. Results Our finding...
Abstract Background To explore the impact of an online continuing medical education (CME) program on physicians’ knowledge about management type two diabetes. Methods An CME was designed and uploaded in platform, Department Education, Ministry health, Iran. A 28-item questionnaire used for assessment. In beginning, a case scenario introduced. Then, participants were asked to follow answer pretest Details educational content provided afterward. Finally, took part same post-test exam 4 weeks...
Selective immunoglobulin A (IgA) deficiency is the most common of primary immunodeficiencies with a frequency 1/300-1/3000, depending on screened population. As secretory IgA (SIgA) has protective role in mucosal surfaces from invasion microorganisms, it thought that IgA-deficient subjects are susceptible to periodontal diseases and oral manifestations. Previous studies show contradictory results, concerning involvement individuals' periodontium deficiency. The aim this study was investigate...
In the early 2000s, Iranian stem cell research and technology had a relatively strong start that benefited from religious blessings, political public support, as well scientific endeavors on part of non-governmental organizations universities. Later on, it developed dynamic niche market public, private start-up, spin-off companies pioneered in Islamic world terms ISI papers, clinical trials, therapy. However, at present, faces new challenges stemming insufficient finance comprehensive law...
The aim of the present study was to determine maternal pre-pregnancy body mass index (BMI), first-trimester fasting blood sugar (FBS), and combination (BMI+FBS) cut-points for at-risk pregnant women conceived by assisted reproductive technology (ART) better predict risk developing gestational diabetes mellitus (GDM) in infertile women.In this nested case-control study, 270 singleton consisted 135 (non-GDM) who using ART were assessed. diagnosis GDM confirmed a one-step glucose tolerance test...
Abstract Background Advanced maternal age, family history of diabetes, pre-gestational obesity, increased level HbA1c, gestational diabetes mellitus (GDM), and poor pregnancy consequences are considered risk factors for antenatal insulin requirement in women with GDM. However, the role assisted reproductive technology (ART) increasing therapy pregnancies complicated GDM remained elusive. The current study aimed to determine ART predicting investigate clinical biochemical need Methods In this...
Phospholipase C zeta 1 (PLCζ) is one of the main sperm factor involved in oocyte activation and other factors may assist this to induce successful fertilization. Microinjection recombinant tr-kit, a truncated form c-kit receptor, into metaphase II-arrested mouse oocytes initiate egg activation. Considering potential roles tr- KIT during spermiogenesis fertilization, we aimed assess expression tr-KIT men with normal abnormal parameters also infertile previous failed fertilization...
This study aimed to determine the prevalence of postpartum metabolic syndrome (MetS), glucose intolerance,<br />and determinants, 6-12 weeks in women with assisted reproduction technology conception<br />gestational diabetes mellitus diagnosis (ART-GDM) compared spontaneous conception and GDM<br />diagnosis (SC-GDM).<br />Materials Methods: In this prospective cohort study, two groups consisting 62 ART-GDM 64 SC-GDM<br />singleton pregnant were followed after delivery for MetS. Fasting...
Although the role of obesity and diabetes mellitus (DM) in male infertility is well established, little information about underlying cellular mechanisms available. In this sense, nuclear factor kappa-B (NF-kB) has been recognized as an important regulator DM; However, its function pathogenesis never studied obese or men who suffer from diabetes. Therefore, main goal current research assessing NF-kB existence activity ejaculated human spermatozoa considering diabetics condition males.In...
The CD133+ bone marrow cell subpopulation includes primitive multipotent stem cells which induce neoangiogenesis. Experimental studies suggested that transplantation of these into infarcted myocardium can have a favorable impact on tissue perfusion and contractile performance. We assessed the feasibility, safety functional outcome autologus BMC during coronary artery bypass grafting (CABG) in patients with recent myocardial infarction. In prospective, non-randomized, open-label study, 27...