A5054931767- Phytochemistry and Biological Activities
- Essential Oils and Antimicrobial Activity
- Fungal Biology and Applications
- Ethnobotanical and Medicinal Plants Studies
- Bee Products Chemical Analysis
- Psidium guajava Extracts and Applications
- Natural product bioactivities and synthesis
- Complementary and Alternative Medicine Studies
- Cardiac Fibrosis and Remodeling
- Marine Sponges and Natural Products
- Phytochemistry and Bioactive Compounds
- Bioactive Compounds and Antitumor Agents
- Pharmaceutical Economics and Policy
- Skin Protection and Aging
- Computational Drug Discovery Methods
- Plant Toxicity and Pharmacological Properties
- Phytochemicals and Antioxidant Activities
- Herbal Medicine Research Studies
- Genomics, phytochemicals, and oxidative stress
- Cardiovascular Function and Risk Factors
- Plant and Biological Electrophysiology Studies
- Seaweed-derived Bioactive Compounds
- Pharmaceutical Quality and Counterfeiting
- Cardiac Ischemia and Reperfusion
- Traditional Chinese Medicine Analysis
University of Lahore
2023-2024
COMSATS University Islamabad
2015-2022
Abbottabad University of Science and Technology
2022
Abbott (Germany)
2017-2021
University of Anbar
2019
Medicinal plants are natural resources of diversified therapeutic metabolites.Lavandula stoechas has been used traditionally for the management different metabolic disorders.However, studies on anticancer characteristics certain bioactive compounds present in this plant very limited.In view this, aim study was to isolate oleanolic acid (a triterpenoid) from L. and assess its trait against breast carcinoma cells (MCF-7) via induced apoptosis.Initially, isolated ethyl acetate fraction using...
Rosa indica L. belongs to the family Rosaceae and is locally known as gulaab. It has different traditional uses in cardiovascular gastrointestinal disorders but there no scientific data available this regard. Therefore, basic aim of study was explore chemical composition effects essential oil obtained from R. indica. The investigated using gas chromatography-mass spectrometry (GC-MS) technique. were electrophysiological measurements. GC-MS analysis showed various components including acetic...
This study aimed to establish the phytochemical profile of Glochidion velutinum and its cytotoxic activity against prostate cancer (PC-3) breast (MCF-7) cell lines. The composition G. leaf extract fractions was established with help total phenolic flavonoid contents LC-MS/MS-based metabolomics analysis. crude methanolic were studied for pharmacological PC-3 MCF-7 lines using MTT assay. content ranged from 44 859 µg GAE/mg sample whereas 20 315 QE/mg sample. A forty-eight compounds...
Contexts: Sauromatum guttatum (Wall.) Schott (Araceae) has been traditionally used for the treatment of wounds.Objectives: This study evaluates healing and tissue regeneration potential S. extract in burn wounds.Materials methods: was analysed using various chemical tests, thin layer chromatography (TLC) high-performance liquid (HPLC). Moreover, tested against associated bacteria minimum inhibitory concentration (MIC) also calculated. Wound assessed a thermally induced BALBc mouse model. (2%...
Context: Psidium guajava L. (Myrtaceae) is widely used in traditional medicine for the treatment of various ailments including cardiovascular and gastrointestinal disorders.Objectives: The current study investigated chemical composition effects essential oil P. guajava.Materials methods: was using gas chromatography-mass spectrometry (GC-MS) technique. biological activity tested on rabbit aorta jejunum. All changes isometric tension were recorded through a force transducer coupled with...
Background: The aim of this study was to evaluate the moisturizing efficacy quince fruit, used in folk medicine. For purpose, phytoconstituents Cydonia oblonga fruit extract, like phenolics and flavonoids, were determined. A stable cosmetic emulgel containing 4% fresh extract formulated subjected vivo evaluation compared with a control. Materials Methods: evaluated for tyrosinase activity phenolic flavonoid content. tested skin irritation test. After this, tests erythema, moisture, sebum,...
Purpose: The current study aimed to determine the phytochemicals and anti-breast cancer potential of Sphaeranthus indicus.Methods: S. indicus flowers were extracted with methanol followed by fractionation using n-hexane. For chemical composition n-hexane fraction, qualitative phytochemical GC-MS analysis performed. anti-proliferative activity was measured MTT assay, whereas, cytotoxic proapoptotic effects in MCF-7 (breast cancer) cells determined propidium iodide, 4′,6-diamidino-...
Objective: To evaluate spasmolytic mechanisms of aqueous and methanolic extracts from Distemonanthus benthamianus trunk-bark.Methods: Spasmolytic activities were evaluated in vitro on spontaneous potassium chloride-induced jejunum contractions, or against cholinergic [acetylcholine (0.3 μmol/L)] stimulations. High performance liquid chromatography analysis both was performed reference to standard compounds.Results: Extracts developed concentration-dependent inhibitory activities. The...
Dermatitis is skin disorder that complicated by recurrent infections of bacteria, viruses, and fungi. Spilanthol an active constituent Spilanthes acmella, which possess strong anti-bacterial properties. The purpose this study was to develop a herbal emulgel for the treatment dermal bacterial infections, as microscopic organisms have created solid resistance against anti-microbials.Emulgels were prepared characterized parameters such physical examination, rheological studies, spreading...
The current study was aimed to investigate the extracts from Heliotropium strigosum and Trapa bicornis phytochemically for various constituents pharmacologically gastro-intestinal disorders. Phytochemical analysis indicated presence of alkaloids, flavonoids, glycosides tannins in both extracts. In castor oil-induced diarrhea, H. T. bicornis, at 100-1000 mg/kg dose provided protection 10-83% 14-76% respectively. isolated rabbit jejunum preparations, (0.01-5 mg/mL) relaxed spontaneous K+ (80...
This study aimed to evaluate the anti-inflammatory effects of a
Background: In traditional medicine, Isodon rugosus is used to treat various ailments, including diabetes. Objectives: The current study aimed identify the pharmacognostic, physicochemical and phytochemical composition investigate I. rugosus's anti-diabetic activity. Methodology: Phytochemical testing was conducted find chemical constituents of rugosus, as it has been reported contain phytochemicals. To perform in-vivo activity, diabetes induced in adult healthy male albino rats after a...
The current study was undertaken to investigate the Jasminum officinale essential oil (Jo.Eoil) for its composition through gas chromatography -mass spectrometry (GC-MS) and pharmacological effects on rabbit jejunum aorta.Antispasmodic activity performed isolated while vasorelaxant effect studied aortic rings using Powerlab data acquisition system.GC-MS analysis indicated 15 constituents in Jo.Eoil.In jejunum, Jo.Eoil exhibited relaxant against spontaneous high concentration K + (80...
The study was carried out by using local organic wastes to investigates the growth of mycelium Ganoderma lucidum Mushroom, produce spawn and prepare a substrate their effect on duration Production efficiency. experimental results different set waste show that minimum growth-period 13.34 days with B, such diffused in cottony compact. On other hand, continues 21.34 21.67 D C, respectively, significant negative variation (P>0.05) non compact mycelia parts. source produced adopted for results....
Myocardial infarction (MI) is the principal cause of premature death. Protecting myocardium from ischemia main focus intense research. 7-hydroxy frullanolide (7-HF) a potent anti-inflammatory agent, showing its efficacy in different acute and chronic inflammatory disorders such as atherosclerosis, suggesting it can be potential cardioprotective agent. For induction MI, Sprague-Dawley rats (n = 5) were administered isoproterenol (ISO) 85 mg/kg s.c at 24 h intervals for two days. The effect...
An experiment has been conducted to investigates the mycelium mushroom growth on 4 types of local organic wastes as well Barley grains for comparison purpose. Also, was prepare 6 substrates a substrate (80% Oak sawdust + 20% wheat bran) cultivation Ganoderma lucidum mushroom. The experimental results different set show that minimum growth-period 13.34 days with SP Palm trunk such diffused in cottony compact, while continue 32 PN date nuclei significant negative variation (P>0.05) poor...