Muhammad Ikram

ORCID: 0000-0002-5877-3837
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Research Areas
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Metal complexes synthesis and properties
  • Synthesis and biological activity
  • Free Radicals and Antioxidants
  • Crystal structures of chemical compounds
  • Inorganic and Organometallic Chemistry
  • Metal-Organic Frameworks: Synthesis and Applications
  • Computational Drug Discovery Methods
  • Nanoparticles: synthesis and applications
  • Advanced Photocatalysis Techniques
  • Enzyme function and inhibition
  • Synthesis and Characterization of Heterocyclic Compounds
  • Enzyme-mediated dye degradation
  • Advanced Nanomaterials in Catalysis
  • Skin Protection and Aging
  • Phytochemicals and Antioxidant Activities
  • Biochemical Analysis and Sensing Techniques
  • Cholinesterase and Neurodegenerative Diseases
  • Chromium effects and bioremediation
  • Crystallography and molecular interactions
  • melanin and skin pigmentation
  • Essential Oils and Antimicrobial Activity
  • Luminescence Properties of Advanced Materials
  • Thermal and Kinetic Analysis

Government College University, Lahore
2024-2025

Abdul Wali Khan University Mardan
2016-2024

Abbottabad University of Science and Technology
2018-2024

COMSATS University Islamabad
2018-2024

Shaanxi Normal University
2024

Kunming University of Science and Technology
2021

Abbott (Germany)
2021

Hazara University
2021

Pusan National University
2018-2019

University of Peshawar
2010-2017

Water pollution due to textile dyes is a serious threat every life form. Bacteria can degrade and detoxify toxic present in effluents wastewater. The study aimed evaluate the degradation potential of eleven bacterial strains for azo dye methyl red. optimum efficiency was obtained using P. aeruginosa. It found from initial screening results that aeruginosa most potent strain with 81.49% activity hence it subsequently used other experiments. To optimize conditions, number experiments were...

10.3390/ijerph19169962 article EN International Journal of Environmental Research and Public Health 2022-08-12

The azo dye orange II is used extensively in the textile sector for coloring fabrics. High concentrations of it are released into aqueous environments through effluents. Therefore, its removal from wastewater and effluents necessary. Herein, initially, we tested 11 bacterial strains their capabilities degradation dye. It was revealed preliminary data that B. subtilis can more potently degrade selected dye, which thus subsequent experiments. To achieve maximum decolorization, experimental...

10.3390/ijms231810637 article EN International Journal of Molecular Sciences 2022-09-13

To obtain a multipotent framework that can target simultaneously COX-2, 5-LOX, acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) to treat neuroinflammation, series of derivatives containing pyrimidine pyrrolidine cores were rationally synthesized evaluated. Pyrazoline–pyrimidine hybrid (23g), (3-acetylcoumarin derivative pyrrolidin-1-yl)benzenesulfonamide (27), tacrine (pyrrolidin-1-yl)benzenesulfonamide (31, 38) displayed excellent in vitro COX-2 inhibition having IC50 value the...

10.1021/acschemneuro.1c00507 article EN ACS Chemical Neuroscience 2021-10-13

The present work was related to synthesis of graphene (0, 1.25 and 2.5 %) incorporation in cobalt-zinc ferrites by using sol–gel auto combustions method. face center cubic (FCC) crystal structure crystallite size varies from 16 18 nm examined XRD analysis. While as the irregular, non-uniform flake like surface morphology cobalt zinc/graphene nanocomposite (Co-Zn-G NCs) were observed via SEM images. In addition, phase identification presence different functional groups such M−O (metal oxide),...

10.1016/j.rinp.2024.107576 article EN cc-by-nc-nd Results in Physics 2024-03-14

Abstract Textile industry releases large quantities of toxic dyes, which is a threat to public health and needs proper management before their release into environment. Out the different approaches used these days, biodegradation bio-decolorization considered an eco-friendly effective technique as this involves use microbes. This has potential be effectively for wide variety dyes. In biological methods, mainly bacteria, fungi, some algae are usually employed remove or decolorize dyes present...

10.1515/zpch-2020-1708 article EN Zeitschrift für Physikalische Chemie 2020-11-25

Targeting concomitantly cholinesterase (ChEs) and monoamine oxidases (MAO-A MAO-B) is a key strategy to treat multifactorial Alzheimer's disease (AD). Moreover, it reported that the expression of cyclooxygenase-2 (COX-2) lipoxygenase (LOX) increased significantly in brain AD patients. Using triazole diclofenac 12 as lead compound, we synthesized variety analogs multipotent inhibitors targeting COX-2, 5-LOX, AChE, BChE, MAO-A MAO-B. A number compounds showed excellent

10.1039/d2ra04183a article EN cc-by-nc RSC Advances 2022-01-01

Currently, numerous ongoing studies are investigating the interaction of free radicals with biological systems, such as lipids, DNA and protein. In present work, synthesis, characterization, antioxidant, binding molecular docking Schiff base ligand its Ni(II), Co(II), Cu(II) Zn(II) were evaluated. The metal complexes have shown significant dose-dependent antioxidant activities higher than those but lesser standard ascorbic acid. constants (Kb) found in order Zn(pimp)2 {9.118 × 105 M-1} >...

10.3390/molecules28155926 article EN cc-by Molecules 2023-08-07

A series of new biologically active complexes Zn(II), Cu(II), Co(II) and Ni(II) with imidazole derivative have been synthesized. The synthesized chelating agent metal(II) were screened for antibacterial activities against four pathogenic species bacteria namely; Eschereschi coli, Pseudomonas aeruginosa, Klesbiella pneumonia Staphylococcus aureus by agar well diffusion method. results show that most the metal more than neat ligand, these bacterial as expected. KEY WORDS:...

10.4314/bcse.v24i2.54743 article EN Bulletin of the Chemical Society of Ethiopia 2010-05-26

Abstract In the current research work, an attempt was made to synthesize silver nanoparticles (MA-AgNPs) utilizing ripened fruit extract of Melia azedarach . Various characterization techniques such as UV-visible spectroscopic analysis, thermal gravimetric analysis (TGA), and scanning electron microscopy (SEM) were used confirm AgNPs synthesis. The bioreduction color changes tracked by spectroscopy while SEM confirmed size 2–60 nm. TGA revealed stability synthesized AgNPs. antibacterial...

10.1515/gps-2023-0029 article EN cc-by Green Processing and Synthesis 2023-01-01
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