A5052234774- Force Microscopy Techniques and Applications
- Cellular Mechanics and Interactions
- Adipose Tissue and Metabolism
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Acute Ischemic Stroke Management
- Coastal wetland ecosystem dynamics
- Extracellular vesicles in disease
- Chromatography in Natural Products
- 3D Printing in Biomedical Research
- Cancer, Lipids, and Metabolism
- RNA Interference and Gene Delivery
- Food Allergy and Anaphylaxis Research
- Adipokines, Inflammation, and Metabolic Diseases
- Cytokine Signaling Pathways and Interactions
- Cancer-related molecular mechanisms research
- Graphene and Nanomaterials Applications
- Food composition and properties
- Lipid Membrane Structure and Behavior
- Fungal Biology and Applications
- Natural product bioactivities and synthesis
- Plant responses to water stress
- Coastal and Marine Dynamics
- Tree Root and Stability Studies
- Neuroscience and Neural Engineering
China National Rice Research Institute
2021-2025
Fujian Medical University
2016-2025
Changchun University of Science and Technology
2015-2024
Guangdong Medical College
2021-2024
Weatherford College
2024
China Agricultural University
2024
Hebei Medical University
2024
Ministry of Agriculture and Rural Affairs
2024
Huazhong Agricultural University
2024
Second Affiliated Hospital of Nanchang University
2024
Abstract Metabolic reprogramming in stromal cells plays an essential role regulating tumour growth. The metabolic activities of tumour-associated macrophages (TAMs) colorectal cancer (CRC) are incompletely characterized. Here, we identify TAM-derived factors and their roles the development CRC. We demonstrate that ABHD5, a lipolytic co-activator, is ectopically expressed CRC-associated macrophages. vitro mouse models macrophage ABHD5 potentiates growth CRC cells. Mechanistically, suppresses...
The aim of this study is to explore signal transducer and activator transcription 3 (STAT3) expression in breast cancer analyze the detailed mechanism that STAT3 contributes progression cancer.We retrospectively analyzed clinicopathologic characteristics overall survival (OS) 140 patients after curative surgery, detected expression, phosphorylated (pSTAT3) Ki-67 vascular endothelial growth factor (VEGF)-C -D tissues, adjacent nontumor tissues. Survival analysis relationship were adopted for...
Abstract The biomechanics stress and chronic inflammation in obesity are causally linked to osteoarthritis. However, the metabolic factors mediating obesity-related osteoarthritis still obscure. Here we scanned identified at least two elevated metabolites (stearic acid lactate) from plasma of diet-induced obese mice. We found that stearic potentiated LDH-a-dependent production lactate, which further stabilized HIF1α protein increased VEGF proinflammatory cytokine expression primary mouse...
Ligands binding to all-inorganic lead halide perovskite nanocrystals (IPNCs) are easy detach from the surface through proton exchange, causing severe stability issues in practical applications. Here, we have reported an amine- and acid-free approach for synthesis of CsPbBr3 IPNC with highly improved photochemical stability. The reaction mechanism follows a trioctylphosphine-mediated passivation route, which provides proton-free environment stabilize ligand capping on IPNCs. Nuclear magnetic...
Novel antimicrobial peptide–modified azithromycin-loaded liposomes against methicillin-resistant Staphylococcus aureus Xiaowei Liu,1,* Zhan Li,1,* Xiaodong Wang,2,3 Yujuan Chen,2,3 Fengbo Wu,2,3 Ke Men,1 Ting Xu,2,3 Yan Luo,1 Li Yang1 1State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, 2Department Thyroid and Breast Surgery, 3Department Pharmacy, West China Hospital, Sichuan University, Chengdu, People’s Republic *These authors contributed equally to this work...
Mangrove fine roots are an important contributor to soil organic matter (SOC), yet how their production and decomposition affect SOC accumulation across the sea-land gradient is still elusive. This study aimed investigate influencing path of biotic abiotic factors root dynamics on component ratios involving particulate carbon (POC)/SOC, dissolved (DOC)/SOC, microbial biomass carbon(MBC)/SOC. Based upon sequential coring litter bag method, production, mangrove were investigated. The turnover...
We fabricated novel rGO-based nanocomposites and analyzed their interaction with drug proteins <italic>via</italic> a molecular dynamics study.
Abstract Background Sarcopenia is a geriatric syndrome with progressive loss of skeletal muscle mass and function has negative impact on clinical outcomes associated chronic obstructive pulmonary disease (COPD). Recently, the sarcopenia index (SI) was developed as surrogate marker based upon serum creatinine to cystatin C ratio. We aimed assess value SI for predicting clinically important among elderly patients acute exacerbation COPD (AECOPD). Methods This cross-sectional study included...
Grain proteins constitute the second most storage substance in rice, of which glutelin accounts for 60%–80% total protein and is easy to be absorbed by humans (Kumamaru et al., 1988). However, patients with kidney disease diabetes, excessive intake not conducive recovery. The lgc-1 mutant earliest discovered low-glutelin material, Lgc-1 regulates content rice grains (Iida 1993; Kusaba 2003), makes this allele have more extensive application prospects cultivation varieties. Rice eating...
Abstract Background Hurricanes and other wind events are significant disturbances that affect coastal urban forests around the world. Past research has led to creation of resistance ratings for different tree species, which can be used in forest management efforts mitigate effects these storms. While useful, have been limited species common forestry Florida, USA. Methods Drawing on past data from a global literature review tropical storm research, we created machine learning model broaden...
Immunogenic chemotherapy is a promising approach in cancer treatment, but the number of drugs capable inducing immunogenic cell death limited, and chronic exposure can delay antitumor immune response be counteracted by immunosuppressive factors. In this study, we used single-cell multilevel analyses to highlight critical importance first calreticulin (CRT) eliciting immunogenicity. We then developed ERASION (endoplasmic reticulum (ER) membrane assist (AS) presentation intrinsic...