A5085904114- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiac and Coronary Surgery Techniques
- Infectious Aortic and Vascular Conditions
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Function and Risk Factors
- Aortic aneurysm repair treatments
- Cardiovascular Issues in Pregnancy
- Coronary Interventions and Diagnostics
- Congenital Heart Disease Studies
- Antimicrobial Resistance in Staphylococcus
- Cardiovascular Disease and Adiposity
- Cardiac Arrhythmias and Treatments
- Vascular anomalies and interventions
- Electrospun Nanofibers in Biomedical Applications
- Cardiac pacing and defibrillation studies
- Mechanical Circulatory Support Devices
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Vascular Anomalies and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Mesenchymal stem cell research
- Cholesterol and Lipid Metabolism
- Tracheal and airway disorders
Hospital Clínico Universitario Virgen de la Victoria
2012-2024
Instituto de Investigación Biomédica de Málaga
2014-2022
Universidad de Málaga
2016-2022
Centro de Investigación Biomédica en Red
2019-2022
Centro de Investigación en Red en Enfermedades Cardiovasculares
2017-2022
Instituto de Salud Carlos III
2018-2022
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
2018-2020
Red de Investigación Cardiovascular
2016-2017
Hospital Clínic de Barcelona
2001
Endocarditis in patients with ascending aortic prosthetic graft (AAPG) is a life-threatening complication. The purpose of this study was to examine the clinical presentation and prognosis AAPG endocarditis included large prospective infectious multicentre study. From January 2008 April 2015, 3200 consecutive according modified Duke criteria, were prospectively ‘Spanish Collaboration on Registry (GAMES)’ registry. Twenty-seven definite episodes (0.8%) occurred AAPG. During period, 27 cases...
Objectives: Sterol regulatory element-binding proteins (SREBP) genes are crucial in lipid biosynthesis and cardiovascular homeostasis. Their expression epicardial adipose tissue (EAT) their influence the development of coronary artery disease (CAD) type-2 diabetes mellitus remain to be determined. The aim our study was evaluate SREBP EAT patients with CAD according status its association clinical biochemical data. Methods: SREBP-1 SREBP-2 mRNA levels were measured from 49 (26 diabetes) 23...
Recent studies have shown that patients with syndromic thoracic aortic aneurysm, particularly bicuspid valve, increased blood levels of transforming growth factor β1 (TGF-β1), indicating this molecule as a prognostic biomarker. However, it is not known whether TGF-β1 also elevated in the tricuspid valve and dilatation. We analysed plasma 52 or normal dilated ascending aorta who underwent cardiac surgery our hospital. level was significantly two-fold compared to aorta. Our results suggest may...
Dilatation of the ascending aorta (AAD) is a prevalent aortopathy that occurs frequently associated with bicuspid aortic valve (BAV), most common human congenital cardiac malformation. The molecular mechanisms leading to AAD BAV are still poorly understood. search for differentially expressed genes in diseased tissue by quantitative real-time PCR (qPCR) an invaluable tool fill this gap. However, studies dedicated identify reference necessary normalization mRNA expression scarce. In report,...
During the last decade, use of ministernotomy in cardiac surgery has increased. Quality life and patient satisfaction after have never been compared to conventional full sternotomy randomised trials. The aim study is determine if this minimally invasive approach improves quality life, clinical morbimortality outcomes. QUALITY-AVR trial a single-blind, single-centre, independent, pragmatic comparing (“J” shaped upper hemisternotomy toward right 4th intercostal space) patients with isolated...
OBJECTIVES: Bicuspid aortic valve (BAV) is the most prevalent congenital cardiac malformation, frequently associated with dilatation (AD). The molecular mechanisms involved in AD and its aetiological link BAV formation are poorly understood. Altered fibrillin-1 (FBN1) metalloprotease-2, -9 (MMP2,9) protein activities have been suggested to be aortopathy. In addition, FBN2 participates embryonic formation, but possible involvement BAV-associated has never explored. this report, we evaluate...
Background: Isolated tricuspid valve surgery is a rarely performed procedure and traditionally associated with bad prognosis, although its clinical outcomes still are little known. The aim of this study was to assess the short- long-term obtained at our center after isolated as treatment for severe regurgitation. Methods: This retrospective included 71 consecutive patients regurgitation who underwent between December 1996 2017. Perioperative mortality, reoperation, functional class were...