A5082031907- Hip disorders and treatments
- Orthopaedic implants and arthroplasty
- Osteoarthritis Treatment and Mechanisms
- Shoulder Injury and Treatment
- Knee injuries and reconstruction techniques
- Total Knee Arthroplasty Outcomes
- Musculoskeletal synovial abnormalities and treatments
- Periodontal Regeneration and Treatments
- Bone and Joint Diseases
- Cardiac Valve Diseases and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Traffic Prediction and Management Techniques
- Silk-based biomaterials and applications
- Spondyloarthritis Studies and Treatments
- Cancer-related molecular mechanisms research
- Sports injuries and prevention
- Musculoskeletal pain and rehabilitation
- Rheumatoid Arthritis Research and Therapies
- Spine and Intervertebral Disc Pathology
- Lower Extremity Biomechanics and Pathologies
- Plant Molecular Biology Research
- Bone Tissue Engineering Materials
- Plant nutrient uptake and metabolism
- Graphene and Nanomaterials Applications
- Myofascial pain diagnosis and treatment
Peking University
2015-2025
Peking University Third Hospital
2015-2025
Affiliated Hospital of Hangzhou Normal University
2009-2025
Hangzhou Normal University
2009-2025
Beijing Sport University
2025
Nanjing University of Information Science and Technology
2023-2024
China Southern Power Grid (China)
2024
China National Nuclear Corporation
2024
First Affiliated Hospital of Fujian Medical University
2018-2024
Fujian Medical University
2018-2024
Four genes of Arabidopsis (At5g20150, At2g26660, At2g45130 and At5g15330) encoding no conservative region other than an SPX domain (SYG1, Pho81 XPR1) were named AtSPX1-AtSPX4. The various subcellular localizations their GFP fusion proteins implied function variations for the four genes. Phosphate starvation strongly induced expression AtSPX1 AtSPX3 with distinct dynamic patterns, while AtSPX2 was weakly AtSPX4 suppressed. Expression AtSPX reduced to different extents in phr1 siz1 mutants...
Arabidopsis thaliana SPX (SYG/PHO81/XPR1) domain genes have recently been shown to be involved in the phosphate (Pi) signaling pathway. We show here that a rice (Oryza sativa) gene, OsSPX1, is specifically induced by Pi starvation roots. Suppression of OsSPX1 RNA interference resulted severe signs toxicity caused over-accumulation Pi, similar found OsPHR2 (phosphate response transcription factor 2) overexpressors and pho2 (phosphate-responsive mutant 2). Quantitative RT-PCR showed expression...
Abstract Introduction Acute post-traumatic brain swelling (BS) is one of the pathological forms that need emergent treatment following traumatic injury. There controversy about effects craniotomy on acute BS. The aim present clinical study was to assess efficacy unilateral decompressive craniectomy (DC) or routine temporoparietal patients with Methods Seventy-four BS midline shifting more than 5 mm were divided randomly into two groups: DC group (n = 37) and (control group, n 37). vital...
Knee osteoarthritis (KOA) is common in elderly people, causes pain, loss of physical functioning, and disability. This was a two-arm, superiority, quasi-experimental trial. The aim this study to evaluate the effectiveness home-based exercise intervention (HBEI) reduce KOA symptoms improve functioning patients. A total 171 patients (60 years age or older) with were recruited from four community centers. Patients two centers randomly assigned group (IG) other control (CG). Participants IG...
Abstract Articular cartilage injury is still a significant challenge because of the poor intrinsic healing potential cartilage. Stem cell-based tissue engineering promising technique for repair. As defects are usually irregular in clinical settings, scaffolds with moldability that can fill any shape and closely integrate host desirable. In this study, we constructed composite scaffold combining mesenchymal stem cells (MSCs) E7 affinity peptide-modified demineralized bone matrix (DBM)...
The regeneration of osteochondral tissue necessitates the re-establishment a gradient owing to unique characteristics and healing potential chondral osseous phases. As self-healing capacity hyaline cartilage is limited, timely mechanical support during neo-cartilage formation crucial achieving optimal repair efficacy. In this study, we devised biodegradable bilayered scaffold, comprising chondroitin sulfate (CS) hydrogel regenerate porous pure zinc (Zn) scaffold for underlying bone as layer....
The rice (Oryza sativa L.) genome contains at least six genes exclusively with an SPX (SYG1/PHO81/XPR1) domain the N-terminal, designated as OsSPX1-6. Here we report diverse expression patterns of OsSPX in different tissues and their responses to Pi-starvation. Among them, five genes, OsSPX1, 2, 3, 5 6 are responsive Pi-starvation shoots and/or roots. subcellular localization analysis indicates that OsSPX1 OsSPX2 is located nucleus, OsSPX3 cytoplasm, OsSPX4 a membrane protein. regulates...
Abstract During July and August of 2022, the Yangtze River Basin (YRB) experienced its most extreme high temperature (EHT) event since 1979, resulting in large numbers human casualties severe economic losses. This paper reveals spatial temporal features EHT over YRB (YRB-EHT) 2022 disentangles nature from a historical perspective. Results showed following: 1) The record-breaking YRB-EHT was directly caused by adiabatic heating associated with an anomalous barotropic pressure (or heat dome)...
Osteoarthritis is a serious disease affecting joint cartilage. Owing to poor blood supply, the meniscus and acetabular labrum of joints heal poorly after injury. However, development artificial alternatives these components that have similar mechanical properties cartilage-protection ability challenging. In this study, strong hydrogel with biomimetic microstructure prepared an emulsion-type photosensitive resin, where both hydrophilic hydrophobic monomers, photo-initiator, drugs can be...
Reduced graft failure rates have been reported after anterior cruciate ligament (ACL) reconstruction combined with anterolateral complex (ALC) augmentation. However, the preoperative diagnosis of concomitant ALC injury remains a clinical challenge.
Hydrogels are attractive for cartilage tissue engineering because of their high plasticity and similarity with the native matrix. However, one critical drawback hydrogels osteochondral repair is inadequate mechanical strength. To address this limitation, we constructed a solid-supported thermogel comprising chitosan hydrogel system demineralized bone Scanning electron microscopy, equilibrium scanning ratio, biodegradation rate, biomechanical tests, biochemical assays, metabolic activity...
Osteoarthritis (OA) is a common, degenerative joint disease characterized by articular cartilage degradation. Currently, clinical trials based on microRNA therapy have been performed to treat various diseases. However, no treatment has found for arthritis. This study investigated the functions of miR-101 in degradation vivo and evaluated feasibility using as therapeutic agent OA. Mono-iodoacetate-induced arthritis (MIA) rats were used an animal model mimic or inhibitor was injected into...