A5083635559- Nanoparticle-Based Drug Delivery
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Advanced Drug Delivery Systems
- Nanoplatforms for cancer theranostics
- Advancements in Transdermal Drug Delivery
- Angiogenesis and VEGF in Cancer
- Phytochemistry and Biological Activities
- RNA Interference and Gene Delivery
- Metal complexes synthesis and properties
- Cholinesterase and Neurodegenerative Diseases
- Pregnancy and preeclampsia studies
- Natural Compound Pharmacology Studies
- Spectroscopy and Chemometric Analyses
- Phytochemistry and Bioactivity Studies
- Pharmacological Effects of Medicinal Plants
- Cancer Mechanisms and Therapy
- Natural Antidiabetic Agents Studies
- Ion Channels and Receptors
- Biological Stains and Phytochemicals
- Seed and Plant Biochemistry
- Crystallization and Solubility Studies
- Chemical synthesis and alkaloids
- Synthesis of Tetrazole Derivatives
- Tea Polyphenols and Effects
Anadolu University
2011-2024
Eskişehir City Hospital
2011-2024
Usak University
2016
Eskişehir Osmangazi University
2016
Nanoparticle (NP) systems have attracted the attention of researchers in recent years due to their advantages, such as modified release features, increased therapeutic efficacy, and reduced side effects. Ferulic acid (FA) has effects anti-inflammatory, anti-Alzheimer's, antioxidant, antimicrobial, anticancer, antihyperlipidemic, antidiabetic. In this study, FA-loaded PLGA-based NPs were prepared by a nanoprecipitation method effect varying concentrations Poloxamer 188 Span 60 on NP...
Journal Article Biting Deterrence, Repellency, and Larvicidal Activity of Ruta chalepensis (Sapindales: Rutaceae) Essential Oil Its Major Individual Constituents Against Mosquitoes Get access Abbas Ali, Ali 2 1National Center for Natural Products Research, The University Mississippi, University, MS 38677. 2Corresponding author, e-mail: aali@olemiss.edu. Search other works by this author on: Oxford Academic PubMed Google Scholar Betul Demirci, Demirci 3Department Pharmacognosy, Faculty...
Objective: The effect of polymers used in nanoparticle (NP) production on the formulation properties is one few studied issues. Therefore, this study aims to formulate flurbiprofen (FLB) loaded NPs with different molecular weight (Mw) poly lactic-co-glycolic acid (PLGA) and investigate Mw NP character. One most important objectives provide a high anti-inflammatory low dose efficacy selected optimal be determined by vivo hen's egg test Chorioallantoic Membrane (HET-CAM) analysis that new,...
Context. Hypericum species including confertum Choisy, H. hircinum L., hyssopifolium Chaix. subsp. elongatum (Ledeb.) Woron var. microcalycinum (Boiss. & Heldr.) Boiss. and perforatum L. (Clusiaceae) are used as medicinal plants in Turkey.
Volatile compounds of green and roasted beans Coffea arabica L. (Rubiaceae) were investigated by this study.Volatile trapped with Headspace Solid-Phase Microextraction (HS-SPME) technique analyzed Gas Chromatography-Mass Spectrometry (GC/MS).The main components the coffee identified as isoamylalcohol (10.4%), hexanal (10.4%) hexacosane (8.2%) while furfurylalcohol (13.6%), furfurylacetate (10.7%) 5-methyl furfural (9.27%) coffee.In conclusion, using HP-SPME-GC-MS, it was possible to quantify...
Ketorolac tromethamine (KT) is a non-steroidal anti-inflammatory drug from the heteroaryl acetic acid derivatives family. The most widely used new nanotechnological approaches for topical delivery are polymeric nanoparticles (NPs).Successful results have been obtained with low doses in many treatments, such as cancer, antimicrobial, pain, made nanoparticle formulations of active ingredients.NPs were prepared using Nano Spray-Dryer. cytotoxicity optimum formulation BJ (ATCC® CRL-2522™) human...
The inhibition of autophagy using pharmacological inhibitors such as chloroquine may be an effective strategy to overcome chemotherapy or resistance anti-angiogenic therapy.The cytotoxic effect doxorubicin (0.1-1 μM), (0.25-32 μM) and their combination were investigated by employing ATP assay in human umbilical vein endothelial cells (HUVECs). was also measured tube formation on Matrigel. activities (2.5 μg/pellet) (15 μg/pellet), combination, standards (50 tested vivo the chick embryo...
Background: Angiogenesis is a natural and complex mechanism that regulated by biomolecules formed the body. Medicinal inorganic chemistry increasing in popularity due to metal-based compounds, offering significant chances possibilities for building novel anti-cancer medicines with promising anti-angiogenic effects. Objective: This study aimed examine successful results obtained from treatments nanoparticle formulations of active drug substances. Methods: The nanoprecipitation/solvent...
Background: Numerous pharmaceutical applications for chitosan, a polysaccharide made from the shells of crustaceans by deacetylating chitin that occurs naturally, are currently being researched. Chitosan, natural polymer, is successfully used to prepare many drug-carrier systems, such as gel, film, nanoparticle, and wound dressing. Objective: Preparing chitosan gels without external crosslinkers less toxic environmentally friendly. Methods: Chitosan-based containing Helichrysum pamphylicum...
In this study, 1-(4-(trifluoromethyl)benzyl)-1H-imidazole, (ImCF3) and 2,2′-bipyridyl, (bipy) ligands coordinating copper(II) complex have been synthesized successfully characterized by single crystal X-ray diffraction, FT-IR UV-vis elemental analysis techniques. The agreement between experimental theoretical results observed. Information about local global chemical activity, electrophilic nucleophilic nature of theoretically obtained. anti-angiogenic activity indicated that showed...
Asetilkolinesteraz (AChE) ve bütirilkolinesteraz (BChE) inhibisyonu, beyinde β-amiloit birikimini azaltmak asetilkolin kullanımını artırmada, yani Alzheimer hastalığının (AD) tedavisinde önemli hedeflerden biridir. Oksidatif stres nedeniyle oluşan serbest radikallerin nöron metal akümülasyonuna verdiği hasar AD’nin patojeneziyle doğrudan ilişkilidir. Amaryllidaceae familyası üyelerinin (Galanthus, Leucojum v.b.) içerdiği galantamin, senile demansın kullanılan AChE inhibitörlerinden Bu...