A5084058814- Urological Disorders and Treatments
- Pediatric Urology and Nephrology Studies
- Urologic and reproductive health conditions
- Urinary and Genital Oncology Studies
- Ureteral procedures and complications
- Tissue Engineering and Regenerative Medicine
- Genital Health and Disease
- Congenital Diaphragmatic Hernia Studies
- Renal and Vascular Pathologies
- Kidney Stones and Urolithiasis Treatments
- Congenital Anomalies and Fetal Surgery
- Electrospun Nanofibers in Biomedical Applications
- Hernia repair and management
- Urinary Bladder and Prostate Research
- Esophageal and GI Pathology
- Bladder and Urothelial Cancer Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Childhood Cancer Survivors' Quality of Life
- Patient-Provider Communication in Healthcare
- Restraint-Related Deaths
- Cerebrospinal fluid and hydrocephalus
- Fetal and Pediatric Neurological Disorders
- Intestinal Malrotation and Obstruction Disorders
- Animal testing and alternatives
- Anatomy and Medical Technology
Evelina London Children's Healthcare
2016-2025
King's College London
2024-2025
Guy's and St Thomas' NHS Foundation Trust
2014-2024
St Thomas' Hospital
2024
Institute of Child Health
2020-2024
University College London
2012-2023
Great Ormond Street Hospital
2012-2022
National Institute for Health Research
2022
UCL Australia
2012
Hospital Universitario La Paz
2011
Management of intestinal failure remains a clinical challenge and total parenteral nutrition, elongation and/or transplantation are partial solutions. In this study, using detergent-enzymatic treatment (DET), we optimize in rats new protocol that creates natural scaffold, as base for developing functional tissue. After 1 cycle DET, histological examination SEM TEM analyses showed removal cellular elements with preservation the native architecture connective tissue components. Maintenance...
In Brief Objective: We aimed to evaluate the effect of thoracoscopy in neonates on intraoperative arterial blood gases, compared with open surgery. Background: Congenital diaphragmatic hernia (CDH) and esophageal atresia tracheoesophageal fistula (EA/TEF) can be repaired thoracoscopically, but this may cause hypercapnia acidosis, which are potentially harmful. Methods: This was a pilot randomized controlled trial. The target number 20 (weight > 1.6 kg) were either (5 CDH, 5 EA/TEF) or...
No AccessJournal of UrologyPediatric Urology1 Jan 2014Primary Bladder Exstrophy Closure in Neonates: Challenging the Traditions I. Mushtaq, M. Garriboli, N. Smeulders, A. Cherian, D. Desai, S. Eaton, P. Duffy, and Cuckow MushtaqI. Mushtaq Department Pediatric Urology, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom , GarriboliM. Garriboli Surgery, UCL Institute Child Health, SmeuldersN. Smeulders CherianA. Cherian DesaiD. Desai EatonS. Eaton DuffyP. Duffy CuckowP....
Objective Boys born with posterior urethral valves (PUV) often experience bladder development issues due to obstruction during gestation. Despite early surgical intervention, dysfunction can persist, leading detrusor overactivity and vesical overdistension. Successful toilet training is key in managing function controlling intravesical upper urinary tract pressures. This study aims evaluate outcomes children PUV. Study design single-centre ambispective cohort included 142 aged 4 years older...
ABSTRACT Purpose To report our preliminary experience on the use of Botulinum toxin A in boys with posterior urethral valves for treating detrusor overactivity and/or reduced bladder compliance not responsive to medical treatment. Material and Methods Primary outcome measures studied were change baseline end fill pressure (pDet), compliance, maximum Detrusor (DO), fractional capacity (FBC), vesicoureteric reflux (VUR) grade/resolution. Secondary serum creatinine estimated glomerular...
Functional smooth muscle engineering requires isolation and expansion of cells (SMCs), this process is particularly challenging for visceral tissue where progenitor have not been clearly identified. Herein we showed the first time that efficient SMCs can be obtained from human amniotic fluid stem (hAFSCs). Clonal lines were generated c-kit(+) hAFSCs. Differentiation toward SM lineage (SMhAFSCs) was using a medium conditioned by PDGF-BB TGF-β1. Molecular assays revealed higher level α actin...
No AccessJournal of UrologyPediatric Urology1 Feb 2020Urodynamic Outcomes in Children after Single and Multiple Injections for Overactive Low Compliance Neurogenic Bladder Treated with Abobotulinum Toxin A Shehryer Naqvi, Joanna Clothier, Anne Wright, Massimo Garriboli NaqviShehryer Naqvi Evelina London Childrens Hospital, London, United Kingdom More articles by this author , ClothierJoanna Clothier WrightAnne Wright GarriboliMassimo *Correspondence: E-mail Address: [email protected]. View...
This educational article highlights the critical role of pediatric urology nursing research in improving care children with urological conditions. It discusses multifaceted nature nursing, addresses challenges such as limited nurse scientists and resource constraints, need to overcome barriers increase involvement. The authors emphasize importance prioritizing areas, promotion collaboration, provision adequate funding academic time for nurses contribute evidence-based practice, improve...
Enterocystoplasty is adopted for patients requiring bladder augmentation, but significant long-term complications highlight need alternatives. We established a protocol creating natural-derived extracellular matrix (BEM) developing tissue-engineered bladder, and investigated its structural functional characteristics.Porcine bladders were de-cellularised with dynamic detergent-enzymatic treatment using peristaltic infusion. Samples fresh controls evaluated histological staining,...