Zhongtao Zhang

ORCID: 0000-0001-5392-5072
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About
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Research Areas
  • Gut microbiota and health
  • Helicobacter pylori-related gastroenterology studies
  • Pancreatic and Hepatic Oncology Research
  • Dysphagia Assessment and Management
  • Traditional Chinese Medicine Analysis
  • Gastroesophageal reflux and treatments
  • thermodynamics and calorimetric analyses
  • ATP Synthase and ATPases Research
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Mechanisms of cancer metastasis
  • Cancer Immunotherapy and Biomarkers
  • Heat shock proteins research
  • Cancer Research and Treatments
  • Radiomics and Machine Learning in Medical Imaging
  • Colorectal Cancer Surgical Treatments
  • Colorectal Cancer Screening and Detection
  • Digestive system and related health
  • AI in cancer detection
  • Phytochemistry and Biological Activities
  • Bioactive Natural Diterpenoids Research

Beijing Friendship Hospital
2014-2024

Capital Medical University
2014-2024

National Clinical Research Center for Digestive Diseases
2017-2024

Jilin Medical University
2022

Background Artificial neural network (ANN) has demonstrated the ability to assimilate information from multiple sources enable detection of subtle and complex patterns. In this research, we evaluated an ANN model in diagnosis pancreatic cancer using serum markers. Methods retrospective analysis, 913 specimens collected at Department General Surgery Beijing Friendship Hospital were analyzed for carbohydrate antigen 19-9 (CA19-9), 125 (CA125), carcinoembryonic (CEA). The three tumor marker...

10.3760/cma.j.issn.0366-6999.20133101 article EN cc-by-nc-nd Chinese Medical Journal 2014-05-20

Abstract Heat shock factor 4 (HSF4) is a member of the HSF family. In this study, by using data from Cancer Genome Atlas‐Colorectal (TCGA‐CRC), we investigated expression profile and prognostic value HSF4 in terms overall survival (OS) recurrence free (RFS) CRC patients. RNA‐Seq showed that RNA was significantly higher tissues ( N = 380) than corresponding normal 51) (mean ± SD: 3.56 1.28 vs. 1.85 0.87, P < 0.0001). High group had ratio stages III/IV patients (52/86, 60.5%) low (110/264,...

10.1002/iub.1692 article EN IUBMB Life 2017-11-13

Metastasis-associated in colon cancer-1 (MACC1) is a recently discovered gene associated with cancer metastasis,there significant relationship indicated from some studies between MACC1 and different malignant tumors.It may play an important role the regulation of tumors metastasis.This article reviewed expression regulating function cancers including colorectal cancer,hepatic cancer,gastric cancer,lung cancer,ovarian cancer,breast cancer,and so on.It offer clues to find new target for...

10.3760/cma.j.issn.1673-4203.2014.05.015 article EN 国际外科学杂志 2014-05-15

Abstract In order to efficiently extract natural medicines, response surface methodology (RSM)were used for the modeling and optimization of flash extraction total flavonoids determine antioxidant activity extracts obtained from Edgeworthia gardneri (Wall). For optimal combination comprehensive yield (Y), Box-Behnken design (BBD) was improve voltage ( X 1 ), time 2 ethanol concentration 3 liquid-solid ratio 4 ). Based on results single factor test, amount extracted (Wall) Meissn as...

10.21203/rs.3.rs-2270466/v1 preprint EN cc-by Research Square (Research Square) 2022-12-29
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