A5100454358- Fluid Dynamics Simulations and Interactions
- Vibration and Dynamic Analysis
- Turbomachinery Performance and Optimization
- Structural Response to Dynamic Loads
- Composite Structure Analysis and Optimization
- Cavitation Phenomena in Pumps
- Bladed Disk Vibration Dynamics
- Hydraulic and Pneumatic Systems
- Ultrasound and Cavitation Phenomena
- Aerodynamics and Fluid Dynamics Research
- Product Development and Customization
- Icing and De-icing Technologies
- Design Education and Practice
- Manufacturing Process and Optimization
- Tribology and Lubrication Engineering
- Computational Fluid Dynamics and Aerodynamics
- High-Velocity Impact and Material Behavior
- Combustion and Detonation Processes
- Smart Materials for Construction
- Heat Transfer Mechanisms
- Liver Diseases and Immunity
- Magnetic Bearings and Levitation Dynamics
- Mechanical Engineering and Vibrations Research
- Fluid Dynamics and Vibration Analysis
- Fluid Dynamics and Turbulent Flows
Shanghai Jiao Tong University
2015-2024
China Southern Power Grid (China)
2024
Ruijin Hospital
2023
Tongren Hospital
2023
Nanjing University of Aeronautics and Astronautics
2023
Zhejiang University of Technology
2023
Shanghai Chest Hospital
2020-2022
Shanghai Institute of Hematology
2019-2021
Renji Hospital
2019-2021
Collaborative Innovation Centre for Advanced Ship and Deep-Sea Exploration
2018-2020
Objective The significance of the liver-microbiome axis has been increasingly recognised as a major modulator autoimmunity. aim this study was to take advantage large well-defined corticosteroids treatment-naïve group patients with autoimmune hepatitis (AIH) rigorously characterise gut dysbiosis compared healthy controls. Design We performed cross-sectional individuals AIH (n=91) and matched controls (n=98) by 16S rRNA gene sequencing. An independent cohort 28 34 analysed validate results....
Multiple clinical similarities exist between IgG4-related sclerosing cholangitis (IgG4-SC) and primary (PSC), while gut dysbiosis has been extensively studied in PSC, the role of microbiota IgG4-SC remains unknown. Herein, we aimed to evaluate alterations microbiome metabolome PSC.We performed 16S rRNA gene amplicon sequencing faecal samples from 135 subjects with (n=34), PSC (n=37) healthy controls (n=64). A subset (31 IgG4-SC, 37 45 controls) also underwent untargeted metabolomic...
The incidence of lung cancer is increasing worldwide. Although great progress in treatment has been made, the clinical outcome still unsatisfactory. Tripartite motif (TRIM)-containing proteins shown to be closely related tumor progression. However, function TRIM46 largely unknown. Here, amplification was found adenocarcinoma (LUAD) tissues and significantly associated with a poor survival rate. Overexpression wild type increased proliferation LUAD cells glycolysis, promoted xenografts...
A variational method is proposed to study the free vibration of joined cylindrical-conical shells (JCCSs) subjected classical and non-classical boundary conditions. JCCS divided into its components (i.e., conical cylindrical shells) at cone-cylinder junction. The interface continuity geometric conditions are approximately enforced by means a modified principle least-squares weighted residual method. No constraints need be imposed priori in admissible displacement functions for each shell...
Background: Increasing data suggests an interaction between bile acids and intestinal microbiota in the pathogenesis of primary biliary cholangitis (PBC). Bile acid sequestrants are widely used to bind lumen therefore posited impact gut bacteria. Herein we aimed investigate effects cholestyramine on profile microbiome a cohort icteric PBC patients.Results: Thirty-three patients were treated with cholestyramine, serum stool samples collected at baseline, 4 16 weeks. Shotgun metagenomic...
Stress can disrupt endocrine signalling in the male reproductive axis through high concentrations of glucocorticoids, hallmark stress. Our previous work revealed that a stress level exogenous glucocorticoids could induce apoptosis rat Leydig cells, which are primary source testosterone. The aim this study was to investigate whether cells vivo and, if so, process is result direct effect glucocorticoids. In chronically stressed model, serum corticosterone concentration increased significantly...