A5103283981- Genetic and phenotypic traits in livestock
- Gut microbiota and health
- Animal Nutrition and Physiology
- Genetic Mapping and Diversity in Plants and Animals
- Probiotics and Fermented Foods
- Meat and Animal Product Quality
- Genomics and Phylogenetic Studies
- Ocular Disorders and Treatments
- Cancer-related molecular mechanisms research
- Bacteriophages and microbial interactions
- Ruminant Nutrition and Digestive Physiology
- Clostridium difficile and Clostridium perfringens research
- Microbial Metabolism and Applications
- Molecular Biology Techniques and Applications
- Autophagy in Disease and Therapy
- Cannabis and Cannabinoid Research
- Animal Genetics and Reproduction
- Shoulder and Clavicle Injuries
- Peroxisome Proliferator-Activated Receptors
- Sirtuins and Resveratrol in Medicine
- Birth, Development, and Health
- Dermatology and Skin Diseases
- Adipose Tissue and Metabolism
- Trauma Management and Diagnosis
- Diet and metabolism studies
Nanchang Normal University
2021-2025
Jiangxi Agricultural University
2013-2023
Chongqing Normal University
2023
Zhejiang Hospital
2022
Zhejiang University
2022
Sichuan Agricultural University
2015-2020
Gut microbiota plays an important role in pig health and production. Still, availability of sequenced genomes functional information for most gut microbes remains limited. Here we perform a landscape survey the swine microbiome, spanning extensive sample sources by deep metagenomic sequencing resulting expanded gene catalog named integrated (PIGC), containing 17,237,052 complete genes clustered at 90% protein identity from 787 metagenomes, which 28% are unknown proteins. Using binning...
Abstract Background Excessive fat accumulation of pigs is undesirable, as it severely affects economic returns in the modern pig industry. Studies humans and mice have examined role gut microbiome host energy metabolism. Commercial Duroc are often fed formula diets with high protein contents. Whether how under this type diet regulates swine largely unknown. Results In present study, we systematically investigated correlation lean meat percentage (LMP) 698 commercial found that Prevotella...
Thousands of QTLs for meat quality traits have been identified by linkage mapping studies, but most them lack precise position or replication between populations, which hinder their application in pig breeding programs. To localize to genomic regions, we performed a genome-wide association (GWA) study using the Illumina PorcineSNP60K Beadchip two swine populations: 434 Sutai pigs and 933 F2 from White Duroc×Erhualian intercross. Meat traits, including pH, color, drip loss, moisture content,...
The size and type of ears are important conformation characteristics that distinguish pig breeds. A significant quantitative trait locus (QTL) for ear has been identified on SSC5 (SSC Sus scrofa chromosome) but the underlying causative gene mutation remain unknown. Thus, our aim was to identify responsible enlarged in pig.First, we narrowed down QTL region a 137.85-kb interval harbors only methionine sulfoxide reductase B3 (MSRB3) gene. Then, 38.7-kb copy number variation (CNV) affects last...
The urgent need for efficient decontamination of organic dyes from polluted waters necessitates the search a low-cost and suitable adsorbent. large amount lemon peel residue in actual production can be an ideal raw material preparation adsorbents. Herein, novel magnetic nanocomposite derived (Citrus limon L.) (Fe3O4/Lp-biochar) was successfully synthesized by one-step hydrothermal method used adsorptive capture methylene blue (MB) aqueous solution. prepared Fe3O4/Lp-biochar are spherical...
Abstract Background Preeclampsia is a pregnancy-specific disease leading to maternal and perinatal morbidity. Hypertension inflammation are the main characteristics of preeclampsia. Many factors can lead hypertension inflammation, including gut microbiota which plays an important role in humans. However, alterations microbiome fecal metabolome, their relationships severe preeclampsia not well known. This study aims identify biomarkers significantly associated with provide knowledge base for...
Gut microbiota plays important roles in host metabolism. Whether and how much the gut different locations contributes to variations of serum metabolites are largely unknown, because it is difficult obtain microbial samples from on a large population scale. Here, we quantified compositions using 16S rRNA gene sequencing for 1070 collected ileum, cecum faeces 544 F6 pigs mosaic pig population. Untargeted metabolome measurements determined profiles. We found 1671, 12,985 103,250 significant...
Increasing evidence indicates that the gut microbiome plays an important role in host aging and sexual maturity. However, microbial taxa associated with maturity quails are unknown. This study used shotgun metagenomic sequencing to identify bacterial d 20 70 quails. We found 17 species 67 metagenome-assembled genomes (e.g., Bacteroides spp. Enterococcus spp.) significantly differed between groups, including 5 faecalis) enriched group 12 Christensenella massiliensis, Clostridium sp. CAG:217,...
The establishment of the piglet gut microbiome has a prolonged influence on host health, as it sets stage for adult swine microbiome. Substantial changes in metabolism and immunity around time weaning may be accompanied by alterations In this study, we systematically evaluated differences metabolites among three periods using shotgun metagenomic sequencing untargeted metabolomic profiling piglets.We identified that P. copri was most significantly different species periods, key bacterial...
PI3K-Akt-mTOR signaling pathway is associated with endoplasmic reticulum (ER) stress. However, it not clear how this affects the ER The present study aimed to determine whether regulates tunicamycin (TM)-induced increases in mRNA levels of genes involved stress, help elucidate mechanism by which stress primary goose hepatocytes. Primary hepatocytes were isolated from geese and cultured vitro. After 12 h a serum-free medium, incubated for 24 medium either no addition (control) or...
Meat production from the commercial crossbred Duroc × (Landrace Yorkshire) (DLY) pig is predominant in pork industry, but its meat quality often impaired by low ultimate pH (pHu). Muscle glycogen level at slaughter closely associated with pHu and technological quality, genetic basis remains elusive. The aim of this study was to identify genes and/or causative mutations muscle other traits performing a genome-wide association (GWAS) additional analyses population 610 DLY pigs. Our initial...
With increasing societal development and the concurrent improvement in people's quality of life, meat consumption has gradually changed from a focus on "quantity" to "quality". Broiler production is increasingly used as means improve by altering various characteristics, especially its genetic factors. However, until now, little been known about variants related traits Chinese purebred chicken populations. To better understand these underpinnings, total 17 carcass were measured 325 Ningdu...
Growth-related traits are economically important to the pig industry. Identification of causative gene and mutation responsible for growth-related QTL will facilitate improvement growth through marker-assisted selection. In this study, we applied whole genome expression quantitative trait transcript (QTT) analyses in 497 liver 586 longissimus dorsi muscle samples identify candidate genes dissect genetic basis a white Duroc × Erhualian F 2 resource population. A total 20,108 transcripts...
Host-associated gut microbial communities are key players in shaping the fitness and health of animals. However, most current studies have focused on bacteria, neglecting important fungal archaeal components these communities. Here, we investigated fungi archaea community composition Large White piglets using shotgun metagenomic sequencing, systematically evaluated how association with microbiome, functional capacity, serum metabolites varied across three weaning periods.We found that...
Abstract Background Bacteriophages are prokaryotic viruses that rank among the most abundant microbes in gut but remain least understood, especially quails. In this study, we surveyed bacteriophage communities 22 quails at different ages (days 20 and 70) using shotgun metagenomic sequencing. We then systematically evaluated relationships with bacteria host serum metabolites. Results discovered Myoviridae Siphoviridae were dominant families Through a random forest LEfSe analysis, identified...
As societal progress elevates living standards, the focus on meat consumption has shifted from quantity to quality. In broiler production, optimizing quality become paramount, prompting efforts refine various attributes. Recent advancements in sequencing technologies have revealed genome’s complexity, surpassing previous conceptions. Through experimentation, numerous genetic elements been linked crucial traits chickens. This review synthesizes current understanding of determinants associated...
Chinese indigenous chickens have a long history of natural and artificial selection are popular for their excellent meat quality unique flavor. This study investigated six quality-related traits in Ningdu yellow, Baier Kangle, Shengze 901 chickens. Two-dimensional gas chromatography-time-of-flight mass spectrometry was used to detect flavors 24 breast muscle samples from the same phenotyped Overall, 685, 618, 502, 487 volatile organic compounds were identified chickens, respectively. The...
The fat mass and obesity-associated gene (FTO) is an excellent candidate that affects energy metabolism.Single nucleotide polymorphisms (SNPs) in FTO are associated with carcass meat quality traits pigs, cattle, rabbits.The aim of this study was to investigate the association between novel SNPs coding region 95 crossbred ducks, using DNA sequencing.We found two transitions G/A (SNP 387 473) within exon 3. SNP a synonymous mutation, whereas 473 missense mutation.Association analysis suggested...
Summary We have generated a large heterogenous stock population by intercrossing eight divergent pig breeds for multiple generations. analyzed the composition of intestinal microbiota at different ages and anatomical locations in > 1,000 6 th - 7 generation animals. show that, under conditions exacerbated genetic yet controlled environmental variability, abundance specific taxa (including Christensenellaceae ) are heritable this monogastric omnivore. fine-map QTL with major effect on...