A5067300662- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Medical Image Segmentation Techniques
- Prostate Cancer Treatment and Research
- Hepatitis B Virus Studies
- Radiopharmaceutical Chemistry and Applications
- Lung Cancer Diagnosis and Treatment
- Immune responses and vaccinations
- Diabetes and associated disorders
- AI in cancer detection
- SARS-CoV-2 and COVID-19 Research
- Medical Imaging and Analysis
- Venous Thromboembolism Diagnosis and Management
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Vasculitis and related conditions
- Cell Image Analysis Techniques
- Advanced X-ray Imaging Techniques
- MRI in cancer diagnosis
- Gut microbiota and health
- Image Processing Techniques and Applications
- Advanced Fluorescence Microscopy Techniques
- Vibrio bacteria research studies
University of Szeged
2013-2024
Heidelberg University
2011
Background: A large number of studies have proved that prostate-specific membrane antigen-positron emission tomography/computer tomography (PSMA-PET/CT) provides excellent accuracy in primary staging and restaging prostate cancer. Less data exist with PSMA-single photon computed (SPECT)/CT investigations. Objective: The aim this study was to evaluate the performance [ 99m Tc]Tc-PSMA-I&S (for imaging surgery) Design methods: We retrospectively analysed PSMA-SPECT/CT scans 20 healthy...
<sup>99m</sup>Tc-PSMA I&S is a prostate-specific membrane antigen (PSMA) tracer that can be used for planar and SPECT/CT γ-imaging radioguided surgery. The primary aim of this study was to estimate the dosimetry using hybrid method (sequential γ-planar imaging 1 single SPECT/CT) in healthy volunteers. secondary depict biodistribution tumor-to-background ratios (TBRs) patients with prostate cancer (PCa). <b>Methods:</b> Dosimetry investigated 4 Whole-body acquired at 1, 2, 3, 6, 24 h 6...
Bacillus Calmette-Guérin (BCG) vaccination has been implicated in protection against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and as a non-specific immunisation method the virus. We therefore decided to investigate T-cell B-cell epitopes within BCG-Pasteur strain proteome for similarity immunogenic peptides of SARS-CoV-2.We used NetMHC 4.0 BepiPred 2.0 epitope prediction methods analysis identify similar established novel SARS-CoV-2 epitopes.We found 112 BCG...
ABSTRACT Chlamydiae are obligate intracellular bacteria that propagate in the inclusion, a specific niche inside host cell. The standard method for counting chlamydiae is immunofluorescent staining and manual of chlamydial inclusions. High- or medium-throughput estimation reduction inclusions should be basis testing antichlamydial compounds other drugs positively negatively influence growth, yet low-throughput common approach. To overcome time-consuming subjective counting, we developed an...
Noninvasive body shaping is becoming a growing demand. The aim of this study was to investigate the efficacy and safety combined treatments 1064 nm Nd:YAG 2940 Er:YAG in noninvasive lipolysis skin tightening. Ten females were enrolled, all women's side waist or lower part abdomen treated. In first step, used. As second laser applied. Each woman treated four times, once every 2 weeks. effects determined by comparative photo documentation, circumference measurement, two-dimensional B-mode...
Organ segmentation in the head and neck region is very challenging due to large variability of shape size organs among patients. Accurate consistent organ-at-risk (OAR) regions important radiation treatment planning. This paper presents a fully automated atlas- learning-based method for segmenting three OARs (trachea, spinal cord, parotid glands) multimodal head-and-neck MRI images. The proposed consists main parts. First, probabilistic atlas generated. Then, Random Forest classifier that...
At least 20% of the future liver remnant must function properly after tumor resection to avoid post-hepatectomy failure (PHLF). [99mTc]Tc-mebrofenin scintigraphy and SPECT are unique noninvasive, quantitative methods for evaluating via hepatocellular bilirubin clearance. To evaluate value dynamic SPECT/CT parameters predicting clinically relevant PHLF according ISGLS criteria. Thirty-five patients underwent imaging determine FLR volumetric rate, functional volume total filtration filtration....
Introduction: Large-vessel vasculitis has non-specific clinical symptoms, which can delay the diagnosis. Early recognition and treatment of disease help to avoid late complications. 18 F-FDG-PET detect inflammation vessel wall in early stage with high sensitivity. CT is used localize vasculitis. Aim: To examine performance 18F-FDG-PET/CT patients suspected large-vessel vasculitis, during relapse remission, focusing on activity extent. Method: 43 were evaluated. They classified according...
Ventilation/Perfusion (V/Q) SPECT largely replaced planar V/Q scintigraphy in daily practice for the diagnosis of pulmonary embolism (PE). By inspecting pixel-based ratio quotient images can be generated from data. These facilitate image reporting. However accurate generation CT-based lung mask is necessary. This work presents a fast and simple fully automatic approach SPECT/CT images.
Ziel/Aim Ventilation/Perfusion (V/Q) SPECT largely replaced planar V/Q scintigraphy in daily practice for the diagnosis of pulmonary embolism (PE). The identification lung lobes has important applications disease assessment. However lobe separation is usually done with manual contouring or semi-automatic tools. fuzzy appearance fissures on low-dose CT images makes computer-aided detection a challenging task. On used frequently appear partially and blurred due to partial volume effects...
Introduction Prostate-specific membrane antigen (PSMA) is a transmembrane protein that may be expressed on the surface of prostate cancer (PC) cells. It enables more sensitive and specific diagnosis PC, compared to conventional anatomical imaging. Aim The integration PSMA-based imaging in personalized radiotherapy PC patients evaluation its impact target volume definition if stereotactic body (SBRT) planned for locally recurrent or oligometastatic disease. Patients methods data from 363...
Dynamic renal studies are an important part of nuclear medicine imaging. Making accurate medical diagnosis requires the patient to remain motionless for duration study, which is not always achievable, especially in case children, due long imaging process. Correcting these displacements manually frame by can be a tedious task. Our goal find automatic and fast motion correction algorithm that minimizes kidneys between 2D image frames with various intensity scales studies.
Ziel/Aim Identification of the vertebrae is usually done manually. The automatic labeling can facilitate this task by speeding up process. However appearance on low-dose CT images makes computer-aided vertebra a challenging task. On used separation cervical and thoracic be difficult due to larger slice thickness. This work presents an approach for focusing SPECT/CT clinical protocols using images.